著者

森脇 昭介 宇佐美 孝子 山本 陽子 山内 政之 村上 和重

出版者

公益社団法人 日本臨床細胞学会

雑誌

日本臨床細胞学会雑誌 (ISSN:03871193)

巻号頁・発行日

vol.15, no.2, pp.83-96, 1976 (Released:2010-10-21)

参考文献数

69

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The multinucleated giant cells (MNGC) were revie wed from various viewpoint and were examined cyto diagnostic significance.1. The definition of MNGC give normal cells-me gakaryocytes, osteoclasts, placental syncytial cells-, and above two nuclei and over twice as large as normal cells.2. The formation of MNGC were classified into two groups of syncytium-the fusion of the cells-, and plasmodium-ivision of the nuclei without cyto plasmic division.3. The etiologic classification of MNGC were as follows: In normal tissue, the physiologic MNGC revealed the above cells.The pathologic MNGC origi nated in various conditions-infectious granulation, metabolic and neoplastic lesions.4. The histologic classification were as follows: The epithelial MNGC were included placental syncytial cells, virus infected cells and neoplastic cells. And the others nonepithelial origin were found of histiocytes (macrophages), mesothelial, blood component and other mesencymal cells of numerous conditionsforeign body giant cells, Langhans', Sternberg's giant cell, et al.5. The relation between various lesions of MNGC, and diagnostic value of MNGC were differe from diseases. Specially, Langhans'cells, herpes infected cells, foreign body giant cells, and a few neoplastic cells were diagnostic value. Mostly neoplastic MNGC were nonspecific anaplastic atypical features.6. It is difficult that the cytologic identification of MNGC were differ from various giant cells. There fore, it is necessary that differentiation of allid MNGC is with reference to histopathologic, clinical features and laboratory data colectively.

著者

万代 光一 森脇 昭介 土井原 博義 中西 慶喜 元井 信 池尻 公二

出版者

一般社団法人 国立医療学会

雑誌

医療 (ISSN:00211699)

巻号頁・発行日

vol.44, no.7, pp.711-716, 1990-07-20 (Released:2011-10-19)

参考文献数

22

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各種臓器に発生するblastomaの形態学的共通点あるいは組織発生を明らかにするために, 腎芽腫2例, 肝芽腫1例, 肺芽腫1例および成人の卵巣中胚葉混合腫瘍2例と肝芽腫様の変化を伴つた肝細胞癌の1例を対象とし, 形態学的観察を行うとともに, 上皮系および間葉系組織マーカーについて免疫組織化学的検討を行つた.腎芽腫と肝芽腫は小児例であり, 肺芽腫と中胚葉混合腫瘍は, 成人に発生した. 肺芽腫と中胚葉混合腫瘍は, 形態学的および免疫組織化学的に類似し, 肺芽腫は未分化間葉細胞起源であることが示唆された. 腎芽腫のblastema様細胞にはS-100免疫活性が証明された. また, 部分的に肝芽腫様に組織形態が変化した成人肝細胞癌の1例が経験された.

著者

岩成 治 都 仁哉 中山 理 柳光 寛仁 吉野 直樹 伊達 美江 北尾 学 三浦 弘資 中西 慶喜 森脇 昭介

出版者

特定非営利活動法人日本臨床細胞学会

雑誌

日本臨床細胞学会雑誌 (ISSN:03871193)

巻号頁・発行日

vol.29, no.6, pp.869-876, 1990-11-22

被引用文献数

8