著者

田坂 祐一 田中 亮裕 井門 敬子 田中 守 荒木 博陽

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.40, no.4, pp.208-214, 2014-04-10 (Released:2015-04-10)

参考文献数

7

被引用文献数

18 22

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Pharmacists have increased the provision of pharmaceutical care services to patients. However, the financial benefit of various pharmaceutical interventions has not been well described. In this study, we estimated the original economic impact associated with pharmaceutical interventions by an evidenced-based approach.We classified pharmaceutical interventions into 12 items, which included preventions of serious adverse drug reactions (ADRs), and avoidance of drug interaction. The cost saving associated with preventions of serious ADRs was calculated as ¥2,140,000 per case based on the amount of costs that were paid by the Pharmaceuticals and Medical Devices Agency. Interventions to transvenous antimicrobial therapy were estimated to have a cost saving of ¥190,000 per case based on the literature in Japan. The rates of preventing serious ADRs related to chemotherapy orders, high-risk drugs and others were 5.21%, 3.91% and 2.6%, respectively, based on the literature in the United States. Using this rate, the values of intervention related to chemotherapy orders, high-risk drugs and others were ¥112,000, ¥84,000 and ¥56,000, respectively.The number of interventions was 209 per year, including 3 avoidances of serious ADRs. According to the number of interventions, we calculated that the total cost saving associated with pharmaceutical interventions was ¥22,816,000.This is the first study to estimate the economic impact associated with various pharmaceutical interventions of pharmacists in Japan. Evaluating the economic impact in relation to the pharmaceutical interventions is an important method for assessing the role of pharmacists.

著者

田中 亮裕 渡邉 真一 中野 夏代 宮本 仁志 中西 和雄 流郷 昌裕 伊東 亮治 田内 久道 守口 淑秀 池川 嘉郎 末丸 克矢 長谷川 均 高田 清式 相引 眞幸 安川 正貴 荒木 博陽

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.36, no.4, pp.232-239, 2010 (Released:2012-03-09)

参考文献数

8

被引用文献数

1 1

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This study was undertaken in order to evaluate the effectiveness of interventions by the Department of Infection Control and Prevention in promoting the proper use of antibiotic drugs for methicillin resistant Staphylococcus aureus (MRSA) prescribed to inpatients.We performed 3 interventions : 1.Protocol improvement for anti-MRSA drug use ; 2.Change in alcohol-based handrub and training in hand hygiene and 3.Devised reporting system for drug use.The effects of the interventions were determined by segmented regression analysis of interrupted time series for drug usage and cost before and after the interventions were commenced.The change in slope of drug use was -1.05 vials/1000 inpatients per month (95% Confidence interval (C.I.) -2.84,0.74)and the change in level was -8.21 vials/1000 inpatients (95% C.I.-14.67,-1.75).There was a significant decrease in the ratio of the patients receiving anti-MRSA drugs to MRSA incidence between before and after the interventions.These results suggested that usage of anti-MRSA drugs was immediately reduced by the interventions to promote the proper use of drugs.An ordinary estimate of reduction in costs was ¥29 million per year while a more conservative estimate produced a decrease of ¥20 million per year.These findings suggest that monitoring antimicrobial use and promoting the proper use of antibiotics for MRSA are important roles for pharmacists to perform.