著者

岡井 彰男 五十崎 俊介 山口 巧 田中 守 池川 嘉郎 末丸 克矢 荒木 博陽

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.30, no.1, pp.27-30, 2004-01-10 (Released:2011-03-04)

参考文献数

8

被引用文献数

1

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Triclofos sodium syrup (Tricloryl® syrup) is mainly used for pretreatment in EEG examinations and sedation before CT and MRI. The unpleasant taste of the syrup, however, occasionally causes compliance problems with children. As we had also experienced difficulties in obtaining sufficient supplies of this medicine for a few months, we prepared a chloral hydrate syrup in our hospital as a substitute for triclofos sodium syrup, aiming to reduce the unpleasant taste and smell of chloral hydrate in the process. Stability and sterility were also investigated. The results of a taste test in healthy volunteers showed that the taste and smell of a 4% chloral hydrate syrup were improved by using an apple flavor, aspartame and a simple syrup base. In our stability and sterility study under the storage condition of 4°C with shading over 6 months, the potency of the syrup was maintained (95 %) and there was no bacterial contamination. These results suggest that the 4% chloral hydrate syrup prepared in our hospital as a substitute for triclofos sodium syrup could improve the compliance of children.

著者

田中 亮裕 渡邉 真一 中野 夏代 宮本 仁志 中西 和雄 流郷 昌裕 伊東 亮治 田内 久道 守口 淑秀 池川 嘉郎 末丸 克矢 長谷川 均 高田 清式 相引 眞幸 安川 正貴 荒木 博陽

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.36, no.4, pp.232-239, 2010 (Released:2012-03-09)

参考文献数

8

被引用文献数

1 1

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This study was undertaken in order to evaluate the effectiveness of interventions by the Department of Infection Control and Prevention in promoting the proper use of antibiotic drugs for methicillin resistant Staphylococcus aureus (MRSA) prescribed to inpatients.We performed 3 interventions : 1.Protocol improvement for anti-MRSA drug use ; 2.Change in alcohol-based handrub and training in hand hygiene and 3.Devised reporting system for drug use.The effects of the interventions were determined by segmented regression analysis of interrupted time series for drug usage and cost before and after the interventions were commenced.The change in slope of drug use was -1.05 vials/1000 inpatients per month (95% Confidence interval (C.I.) -2.84,0.74)and the change in level was -8.21 vials/1000 inpatients (95% C.I.-14.67,-1.75).There was a significant decrease in the ratio of the patients receiving anti-MRSA drugs to MRSA incidence between before and after the interventions.These results suggested that usage of anti-MRSA drugs was immediately reduced by the interventions to promote the proper use of drugs.An ordinary estimate of reduction in costs was ¥29 million per year while a more conservative estimate produced a decrease of ¥20 million per year.These findings suggest that monitoring antimicrobial use and promoting the proper use of antibiotics for MRSA are important roles for pharmacists to perform.

著者

末丸 克矢 山下 梨沙子 武市 佳己 山口 巧 公平 恵崇 岡本 千恵 五十崎 俊介 井門 敬子 田中 守 三好 裕二 守口 淑秀 池川 嘉郎 荒木 博陽

出版者

日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.32, no.2, pp.139-145, 2006

参考文献数

8

被引用文献数

11 18

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We have been conducting a four-week practical hospital training course incorporating experience-oriented programs for fourth-year undergraduate students at Ehime University Hospital. There are 17 such programs in the curriculum among them instruction in the self-administration of insulin and bronchial asthma inhalers, nutrition support, drug counseling training using case-based learning procedures and role-play practice (CBL practice), and evidence based medicine (EBM practice) based on the provision of drug information. Self-learning exercises were devised for CBL and EBM practices. At the end of the practical hospital training course, we conducted a questionnaire survey concerning understandability, extent of previous understanding, training time, necessity of each program and degree of satisfaction with it. Analysis of the responses showed that student satisfaction with the practical training program was positively and significantly correlated with understandability (r=0.756, p<0.01) and degree of experience received (r=0.538, p<0.05). However, there was no correlation between satisfaction and previous understanding, training time or necessity. These results suggest that the experience-oriented programs enhanced students' understanding of the hospital practical training and also increased their satisfaction with it.