著者

石丸 博雅 津田 泰正 景 秀典 河野 友昭 高山 慎司 森元 能仁 後藤 一美 渡部 一宏

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.141, no.1, pp.143-150, 2021-01-01 (Released:2021-01-01)

参考文献数

28

被引用文献数

1

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Occupational exposure to anticancer drugs may increase the risk of cancer and the risk of miscarriage and stillbirth, and cause other adverse events such as hypersensitivity reactions, skin/mucous reactions, and digestive symptoms. Several studies have investigated the use of closed-system drug-transfer devices (CSTDs) to reduce the environmental pollution by hazardous drugs. However, few reports have verified whether CSTDs contain the hazardous drugs within the vials. The BD PhaSealTM System is a CSTD that is frequently used in Japan. However, the fit of each anti-cancer drug vial has not been investigated. We investigated the fit of 71 major anti-cancer drug vials and protectors released and frequently used in Japan by means of a pressure compatibility test that we developed. The pressure compatibility test involved attaching a three-way stopcock to a Luer lock syringe and attaching an injector in line with the syringe. The pressure tubing was connected to the other side of the three-way stopcock and connected to the pressure inlet of the pressure gauge. The pressure in the anti-cancer drug vial was raised to 100 kPa and connected/disconnected repeatedly. If the pressure fluctuation during the 10th connection was within 6%, it was defined as “no change”, and the compatibility of the protector and the vial was evaluated. The median pressure reduction rates at the 10th connection ranged from −1.98% to −4.95%. All drugs surveyed had an error rate within 6%. The BD PhaSealTM Protector was shown to be compatible with the 71 anti-cancer drugs we surveyed.

著者

石丸 博

出版者

社会学研究会

雑誌

ソシオロジ (ISSN:05841380)

巻号頁・発行日

vol.30, no.1, pp.77-94,192, 1985-05-31 (Released:2017-02-15)

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One of the focal organizations in interorganizational relations in bureaucracy is the office which plays the role of controlling the activities of each department or ministry. It is possible to devide this control or supervisory office into two types ; 1) the management or integration type and 2) the planning or affainment type. In wartime Japan the Ministry of Finance exemplified the former, and the newly established offices , i. e., the Cabinet Research Bureau (Chosa-kyoku), the Cabinet Planning Agency (Kikaku-cho) and the Cabinet Planning Board (Kikaku-iri) exemplified the latter type. The Finance Ministry came to the fore before the February 26, 1936 Incident. The other side offices tried to gain power after the Incident. That is to say after the Incident, interorganizational relations in bureaucracy showed new structural differentiation or possessed dual focal organizations. In this paper I analysize the conflict processes between two types of control offices after the Incident. I conclude that the Finance Ministry incorporated the Cabinet Planning Board, the last stage of the other side offices, into the interorganizational relations, to great advantage to itself. And it is possible to say that these interorganizational relations, wherein the planning-type control office is incorporated under the influence of the management-type one is the prototype of interorganizational relations in the postwar Japanese bureaucracy which contributes to economic growth.

著者

石丸 博

出版者

愛知教育大学地域社会システム講座

雑誌

社会科学論集 (ISSN:02885778)

巻号頁・発行日

no.40, pp.25-53, 2003