著者

三好 正一 田口 清 青木 創 虻川 孝秀 岡田 洋之 吉野 知男

出版者

公益社団法人 日本獣医師会

雑誌

日本獣医師会雑誌 (ISSN:04466454)

巻号頁・発行日

vol.57, no.9, pp.575-578, 2004-09-20 (Released:2011-06-17)

参考文献数

15

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4歳のホルスタイン種乳牛において分娩後, 食欲の低下とタール便の排泄を認めた. 被毛は粗剛となり脱毛し, 末梢部 (耳介, 尾端) の壊死, 両前膝表皮の脱落および左後肢の壊疽が認められた. 患畜が乾乳中に敷き料として用いられたライ小麦麦秤が赤カビに汚染され, 高濃度のマイコトキシン (デオキシニバレノール) が検出されたこと, また, 患畜がその敷き料を採食していたことから, 発症原因としてマイコトキシン中毒の関与が疑われた.

著者

アレン・フランセス著 青木創訳

出版者

講談社

巻号頁・発行日

2013

著者

古川 敬之 青木 創 藤井 豊 二瓶 和美 鈴木 学 小野 憲一郎 平尾 秀博

出版者

日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.5, no.2, pp.29-34, 2014-12-26 (Released:2014-12-26)

参考文献数

12

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A 9-year-old neutered female Miniature Dachshund had undergone lobectomy of the left frontal lobe for lung carcinoma followed by nine post-operative doses of carboplatin chemotherapy(250 mg/m2, every 3weeks). The dog was referred to the Japan Animal Referral Medical Center (Nagoya), because of lung masses in the opposite right middle and posterior lobes. Whole body contrast-enhanced computed tomography(CT)was performed and revealed lung solitary tumors in the relevant areas. No abnormal findings were observed in other lobes or intrathoracic lymph nodes. Since the possibility of metastatic lesions of lung carcinoma incompletely removed in the previous surgery was considered, we performed CT again on day 45 for evaluation of the new tumor progression. The size of both tumors increased, and right middle and posterior lung lobectomies were carried out on day 53. There were no adhesive lesions around the tumors, carcinomatous pleuritis, pleural fluid or hilar lymphadenopathy. While histopathology revealed high-grade lung adenocarcinoma with numerous mitoses, there was no evidence of intravascular invasion, suggesting complete resection. A tentative diagnosis of metastatic lung tumor(T2N0M1)was made. Adjuvant chemotherapy with carboplatin(250 mg/m2, for every 3 weeks)and piroxicam(0.3 mg/kg/3 days)was also given starting on day 21, and no evidence of recurrent lesions was observed on day 726 with a good health condition maintained. From these results, it is suggested that aggressive surgery plus adjuvant chemotherapy can be appropriate treatments for metastatic lung carcinoma.