著者

HIROKI SHIMURA SHINICHI SUZUKI TOSHIHIKO FUKUSHIMA SANAE MIDORIKAWA SATORU SUZUKI NAOMI HAYASHIDA MISA IMAIZUMI NORIYUKI OKUBO YASUSHI ASARI TAKESHI NIGAWARA FUMIHIKO FURUYA KAZUHIKO KOTANI SHIGEYUKI NAKAJI AKIRA OTSURU TAKASHI AKAMIZU MASAFUMI KITAOKA NOBORU TAKAMURA MASAFUMI ABE HITOSHI OHTO NOBUYUKI TANIGUCHI SHUNICHI YAMASHITA

出版者

福島医学会

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

pp.2014-28, (Released:2014-12-20)

参考文献数

33

被引用文献数

4

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Contents1. Introduction2. Thyroid ultrasound examination in Fukushima3. Thyroid ultrasound findings in children in three Japanese prefectures4. Prevalence of thyroid nodular lesions in children and adolescents 4.1 Thyroid cyst 4.2 Thyroid nodule 4.3 Thyroid cancer5. SummaryConflict of interestReference

著者

HIROKI SHIMURA SHINICHI SUZUKI TOSHIHIKO FUKUSHIMA SANAE MIDORIKAWA SATORU SUZUKI NAOMI HAYASHIDA MISA IMAIZUMI NORIYUKI OKUBO YASUSHI ASARI TAKESHI NIGAWARA FUMIHIKO FURUYA KAZUHIKO KOTANI SHIGEYUKI NAKAJI AKIRA OTSURU TAKASHI AKAMIZU MASAFUMI KITAOKA NOBORU TAKAMURA MASAFUMI ABE HITOSHI OHTO NOBUYUKI TANIGUCHI SHUNICHI YAMASHITA

出版者

THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

vol.60, no.2, pp.196-202, 2014 (Released:2015-02-26)

参考文献数

33

被引用文献数

4

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Contents1. Introduction2. Thyroid ultrasound examination in Fukushima3. Thyroid ultrasound findings in children in three Japanese prefectures4. Prevalence of thyroid nodular lesions in children and adolescents 4.1 Thyroid cyst 4.2 Thyroid nodule 4.3 Thyroid cancer5. SummaryConflict of interestReference

著者

Tsuyako Sakamaki Motohiko Hara Kazunori Kayaba Kazuhiko Kotani Shizukiyo Ishikawa

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20150092, (Released:2015-10-10)

参考文献数

23

被引用文献数

5

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Background: Previous studies on the association between coffee consumption and subarachnoid hemorrhage (SAH) have provided inconsistent results. We examine the risk of SAH from coffee consumption in a Japanese population.Methods: Our analyses were based on the Jichi Medical School Cohort Study, a large-scale population-based prospective cohort study. A total of 9941 participants (3868 men and 6073 women; mean age 55 years) with no history of cardiovascular disease or carcinoma were examined. Participants were asked to choose one of five options to indicate their daily coffee consumption: none, less than 1 cup a day, 1–2 cups a day, 3–4 cups a day, or 5 or more cups a day. The incidence of SAH was assessed independently by a diagnostic committee. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their 95% confidence intervals (CI) after adjustment for age and sex (HR1) and for additional potential confounders (HR2).Results: During 10.7 years of follow-up, SAH occurred in 47 participants. When compared with the participants who consumed less than 1 cup of coffee a day, the HR of SAH was significantly higher in the group who consumed 5 or more cups a day in both models (HR1 4.49; 95% CI, 1.44–14.00; HR2 3.79; 95% CI, 1.19–12.05).Conclusions: The present community-based cohort study showed that heavy coffee consumption was associated with an increased incidence of SAH after adjusting for age, sex, and multiple potential cardiovascular confounders.

著者

Jun Watanabe Kazuhiko Kotani

出版者

THE JAPANESE ASSOCIATION OF RURAL MEDICINE

雑誌

Journal of Rural Medicine (ISSN:1880487X)

巻号頁・発行日

vol.18, no.1, pp.1-7, 2023 (Released:2023-01-06)

参考文献数

57

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Objective: Rural surgical training for residents is expected to increase the number of general surgeons working in rural areas; however, the impact of rural training programs to ensure such surgeons remains to be determined. Therefore, we reviewed the relevance of rural surgical rotation to the increase of general surgeons in rural areas.Materials and Methods: Studies on the outcomes of rural surgical rotations during the residency period in comparison to non-rural surgical rotations were retrieved using electronic databases through April 2022.Results: Among the 514 articles, five were eligible for review. All studies were published in the United States. Four studies reported an increased number of general surgeons in rural areas owing to rural surgical rotations. A meta-analysis of all studies showed a positive impact on the number of general surgeons in rural areas (odds ratio=2.19, 95% confidence interval=1.23–3.91). The programs generally ranged from 2 to 12 months with extensive experience with minor surgery and subspecialties necessary for surgery.Conclusions: Rural surgical rotations during the residency period can increase the number of general surgeons working in rural areas. Further studies are needed to evaluate the placement of general surgeons in rural areas.

著者

Narumi Nagai Satomi Yagyu Anna Hata Shinsuke Nirengi Kazuhiko Kotani Toshio Moritani Naoki Sakane

出版者

SOCIETY FOR FREE RADICAL RESEARCH JAPAN

雑誌

Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)

巻号頁・発行日

pp.18-104, (Released:2019-03-07)

参考文献数

43

被引用文献数

30

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Maslinic acid, derived from olive fruit, reduces pro-inflammation cytokines, which are involved in muscle fiber atrophy. Therefore, the maslinic acid ingestion may enhance the muscular response to resistance training through anti-inflammatory action. We therefore conducted a parallel, double-blind, randomized, placebo-controlled trial that examined whether a combination of maslinic acid supplementation and resistance training improve mobility functions in community-dwelling elderly persons. Over a 12-week period, 36 participants underwent moderate resistance training and are assigned to the maslinic acid supplementation (n = 17, 60 mg/day) or the placebo (n = 19) group. At baseline and at 12-weeks, we assessed body composition, grip strength, walking speed, leg strength, mobility functions, and knee pain scores. Following the 12-weeks, skeletal muscle mass, segmental muscle mass (right arm, left arm, and trunk) and knee pain score of the right leg were significantly improved in the maslinic acid group, while there was no change or parameters had worsened in the placebo group. Grip strength of the better side significantly increased only in the maslinic acid group. These results suggest that maslinic acid supplementation combined with moderate resistance training may increase upper muscle mass and grip strength, and reduce knee pain, could be effective for preventing mobility-related disability in elderly persons. Clinical trial registration number: UMIN000017207.

著者

Tsuyako Sakamaki Motohiko Hara Kazunori Kayaba Kazuhiko Kotani Shizukiyo Ishikawa

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.26, no.2, pp.71-75, 2016-02-05 (Released:2016-02-05)

参考文献数

23

被引用文献数

5

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Background: Previous studies on the association between coffee consumption and subarachnoid hemorrhage (SAH) have provided inconsistent results. We examine the risk of SAH from coffee consumption in a Japanese population.Methods: Our analyses were based on the Jichi Medical School Cohort Study, a large-scale population-based prospective cohort study. A total of 9941 participants (3868 men and 6073 women; mean age 55 years) with no history of cardiovascular disease or carcinoma were examined. Participants were asked to choose one of five options to indicate their daily coffee consumption: none, less than 1 cup a day, 1–2 cups a day, 3–4 cups a day, or 5 or more cups a day. The incidence of SAH was assessed independently by a diagnostic committee. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their 95% confidence intervals (CI) after adjustment for age and sex (HR1) and for additional potential confounders (HR2).Results: During 10.7 years of follow-up, SAH occurred in 47 participants. When compared with the participants who consumed less than 1 cup of coffee a day, the HR of SAH was significantly higher in the group who consumed 5 or more cups a day in both models (HR1 4.49; 95% CI, 1.44–14.00; HR2 3.79; 95% CI, 1.19–12.05).Conclusions: The present community-based cohort study showed that heavy coffee consumption was associated with an increased incidence of SAH after adjusting for age, sex, and multiple potential cardiovascular confounders.

著者

Kazuhiko Kotani Yoshitaka Sekine Shizukiyo Ishikawa Imoh Z. Ikpot Kazuhiro Suzuki Alan T. Remaley

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20130006, (Released:2013-08-27)

参考文献数

35

被引用文献数

10 36

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Prostate cancer is a common disease in modern, developed societies and has a high incidence and mortality. High-density lipoprotein cholesterol (HDL-C) has recently received much attention as a possible risk marker of prostate cancer development and prognosis. In the present article, we summarized findings from epidemiologic studies of the association between HDL-C and prostate cancer. Low HDL-C level was found to be a risk and prognostic factor of prostate cancer in several epidemiologic studies, although the overall linkage between HDL and prostate cancer has not been definitively established. The mechanisms for this association remain uncertain; however, limited data from experimental studies imply a possible role of HDL in the pathophysiology of prostate cancer. More epidemiologic research, in combination with experimental studies, is needed in this field.