著者
MASAMI OHMORI KAZUHIRO HARADA SHUICHI TSURUOKA KOH-ICHI SUGIMOTO EIJI KOBAYASHI AKIO FUJIMURA
出版者
The Japan Endocrine Society
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
vol.46, no.4, pp.579-583, 1999 (Released:2006-11-25)
参考文献数
5
被引用文献数
3 9

Here we report a case of levothyroxine-induced liver dysfunction. T4 (levothyroxine) has been more commonly used for the treatment of hypothyroidism than T3 active hormone (triiodothyronine), because with the former drug a stabler plasma concentration is obtained after oral administration. Although there are few reports on levothyroxine-induced liver dysfunction, we treated a primary hypothyroid patient with high serum aminotransferase after administration of levothyroxine. Liver dysfunction was improved after cessation of the drug administration. Antibody to T4 was found in the serum of the patient after this event. From clinical course and laboratory data of the patient, the episode of liver damage was considered to be induced by levothyroxine. We then administrated triiodothyronine, and it did not induce liver dysfunction. Changing levothyroxine to triiodothyronine resulted in a successful clinical course in this case, as re-administration of the doubtful drug is strictly limited.
著者
Tetsuya Nishikawa Kazuhiro Harada Tsuyoshi Watanabe
出版者
The Plankton Society of Japan, The Japanese Association of Benthology
雑誌
Plankton and Benthos Research (ISSN:18808247)
巻号頁・発行日
vol.17, no.1, pp.83-90, 2022-02-22 (Released:2022-02-23)
参考文献数
40
被引用文献数
1

In the Sea of Japan, changes in the oceanographic conditions affect fisheries, and new phenomena such as blooms of the harmful dinoflagellate Margalefidinium polykrikoides and mass occurrences of the giant jellyfish Nemopilema nomurai have been observed since the 2000s. In order to elucidate and formulate countermeasures to such new issues, it is essential to enhance the oceanographic/biological data. However, data especially on the phytoplankton assemblage are limited. In the present study, we investigated the population dynamics of the phytoplankton community together with environmental factors at two stations off Tajima, southwestern Sea of Japan for seven fiscal years from September 2009 to March 2016. The oceanographic observations revealed the general pattern in the seasonal and annual abundance of phytoplankton off Tajima. The major component of size-fractionated chlorophyll a concentrations were micro-size (filtered pore size: >10 µm). The results indicated that there was usually a low abundance of phytoplankton in this area. Relatively high abundances (cell densities over 100 cells mL−1) of micro-sized phytoplankton were observed only in spring, but total cell densities were less than 10 cells mL−1 in most months of the other three seasons. The major phytoplankton component was diatoms. Based on the abundance and frequency, the dominant seven diatom taxa were classified into three groups: Skeletonema spp., Thalassiosira spp. and Eucampia zodiacus were dominant in spring, Chaetoceros spp. and Pseudo-nitzschia spp. were dominant in spring and autumn, and Rhizosolenia spp. and Leptocylindrus danicus were dominant in autumn.
著者
Saroj Kandel Kazuhiro Harada Sudha Adhikari Nabin Kumar Dahal Maheshwar Dhakal
出版者
日本熱帯生態学会
雑誌
Tropics (ISSN:0917415X)
巻号頁・発行日
pp.MS19-07, (Released:2020-04-15)
参考文献数
51
被引用文献数
7

There is always a conflict of interest between conservation efforts and communities living near conservation areas. Buffer zones and opportunities for ecotourism are sometimes created to lessen the negative impact of the stringent rules involved in conservation which directly impacts the livelihoods of neighbouring communities. This paper examines a Nepalese community’s perceptions of the Buffer Zone Community Forest (BZCF) rules, and investigates the interplay of rules, ecotourism, and human-wildlife conflict (HWC). Data were obtained from face-to-face household surveys and key informant interviews carried out in two Buffer Zone Villages in Chitwan National Park, Nepal. It was found that access to forest resources has become more restricted since ecotourism was introduced in the BZCF. Furthermore, contrary to expectations, settlements both closer to and farther from the forest are largely affected to the same extent by these restrictions. This study recommends better livelihood opportunities for disadvantaged groups in and around the BZCF, along with the development of forest policies based in reality to improve compliance with forest rules and to gain local support for conservation efforts.