著者

Nobuyuki Kagiyama Misako Toki Akihiro Hayashida Minako Ohara Atsushi Hirohata Keizo Yamamoto Toshinori Totsugawa Taichi Sakaguchi Kiyoshi Yoshida Mitsuaki Isobe

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.81, no.11, pp.1730-1735, 2017-10-25 (Released:2017-10-25)

参考文献数

26

被引用文献数

6 8

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Background:As mitral valve (MV) repair for Barlow’s disease remains surgically challenging, it is important to distinguish Barlow’s disease from fibroelastic deficiency (FED) preoperatively. We hypothesized that the prolapse volume to prolapse height ratio (PV-PH ratio) may be useful to differentiate Barlow’s disease and FED.Methods and Results:In 76 patients with MV prolapse who underwent presurgical transesophageal echocardiography, the 3D MV morphology was quantified: 19 patients were diagnosed with Barlow’s disease and 57 with FED. The patients with Barlow’s disease had greater prolapse volume and height than the patients with FED, as well as greater PV-PH ratio (0.61±0.35 vs. 0.17±0.10, P<0.001). Receiver-operating characteristic analysis revealed that with a cutoff value of 0.27, the PV-PH ratio differentiated Barlow’s disease from FED with 84.2% sensitivity and 84.2% specificity. Net reclassification improvement showed that the differentiating ability of the PV-PH ratio was significantly superior to prolapse volume (1.30, P<0.001). After being adjusted by each of prolapse volume and height, annular area and shape, and the number of prolapsed segments, the PV-PH ratio had an independent association with Barlow’s disease.Conclusions:The PV-PH ratio was able to differentiate Barlow’s disease from FED with high accuracy. 3D quantification including this value should be performed before MV repair.

著者

小林 久高 山本 圭三 Hisataka Kobayashi Keizo Yamamoto

出版者

同志社社会学研究学会

雑誌

同志社社会学研究 = The Doshisha Shakaigakukenkyu (Doshisha review of sociology) (ISSN:13429833)

巻号頁・発行日

no.24, pp.55-118, 2020-03-31

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多変量解析の基礎となる回帰分析について、(1)記述統計的な解説、(2)ベクトルを用いた図形的解説、(3)推測統計的解説、(4)数学的解説をしたもの。