文献一覧: Mariko Nakamoto (著者)

6 0 0 0 OA Inverse Correlation Between Coffee Consumption and Prevalence of Metabolic Syndrome: Baseline Survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan

著者: Hidenobu Takami Mariko Nakamoto Hirokazu Uemura Sakurako Katsuura Miwa Yamaguchi Mineyoshi Hiyoshi Fusakazu Sawachika Tomoya Juta Kokichi Arisawa
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.23, no.1, pp.12-20, 2013-01-05 (Released:2013-01-05)
参考文献数: 44
被引用文献数: 58 82

Background: It is unclear whether consumption of coffee and green tea is associated with metabolic syndrome.Methods: This cross-sectional study enrolled 554 adults who had participated in the baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima Prefecture, Japan. Consumption of coffee and green tea was assessed using a questionnaire. Metabolic syndrome was diagnosed using the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the Japan Society for the Study of Obesity (JASSO). Logistic regression analysis was used to examine the association between consumption of coffee and green tea and prevalence of metabolic syndrome and its components.Results: After adjustment for sex, age, and other potential confounders, greater coffee consumption was associated with a significantly lower prevalence of metabolic syndrome, as defined by NCEP ATP III criteria (P for trend = 0.03). Participants who drank more coffee had a lower odds ratio (OR) for high serum triglycerides (P for trend = 0.02), but not for increased waist circumference or high blood pressure. Using JASSO criteria, moderate coffee consumption (1.5 to <3 cups/day) was associated with a significantly lower OR for high plasma glucose (OR = 0.51, 95% CI 0.28–0.93). Green tea consumption was not associated with the prevalence of metabolic syndrome or any of its components.Conclusions: Coffee consumption was inversely correlated with metabolic syndrome diagnosed using NCEP ATP III criteria, mainly because it was associated with lower serum triglyceride levels. This association highlights the need for further prospective studies of the causality of these relationships.

2021-09-08 15:57:44
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6 0 0 0 OA Inverse Correlation Between Coffee Consumption and Prevalence of Metabolic Syndrome: Baseline Survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan

著者: Hidenobu Takami Mariko Nakamoto Hirokazu Uemura Sakurako Katsuura Miwa Yamaguchi Mineyoshi Hiyoshi Fusakazu Sawachika Tomoya Juta Kokichi Arisawa
出版者: 日本疫学会
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: pp.JE20120053, (Released:2012-10-06)
参考文献数: 44
被引用文献数: 23 82 13

2016-08-24 02:59:18
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1 0 0 0 OA Decreased expression of MHC class II and cathepsin E in dendritic cells might contribute to impaired induction of antigen-specific T cell response in NC/Nga mice

著者: Tohru Sakai Emi Shuto Tomoyo Taki Honami Imamura Miku Kioka Akiko Nakamoto Seiji Mizoguchi Shouko Amano Yukari Kawano Mariko Nakamoto Rie Tsutumi Toshio Hosaka
出版者: The University of Tokushima Faculty of Medicine
雑誌: The Journal of Medical Investigation (ISSN:13431420)
巻号頁・発行日: vol.59, no.1,2, pp.95-101, 2012 (Released:2012-03-08)
参考文献数: 16
被引用文献数: 1

NC/Nga (NC) mice are an animal model for human atopic dermatitis. We found that induction of antigen (Ag)-specific T cell response is diminished in ovalbumin (OVA)-immunized NC mice. Ability of Ag presentation in NC mouse dendritic cells (DCs) was significantly weaker than that in BALB/c and DBA/2 mouse DCs. Expression levels of MHC class II molecules and cathepsin E in NC mouse DCs were significantly lower that those in BALB/c and DBA/2 mouse DCs. These results indicate that low expression levels of MHC class II and cathepsin E might contribute to the defect in induction of Ag-specific T cells in NC mice. J. Med. Invest. 59: 95-101, February, 2012

2019-10-05 01:40:19
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1 0 0 0 OA Brazilian Green Propolis Promotes Weight Loss and Reduces Fat Accumulation in C57BL/6 Mice Fed A High-Fat Diet

著者: Tohru Sakai Miyuki Ohhata Misaki Fujii Sayaka Oda Yasuna Kusaka Miki Matsumoto Akiko Nakamoto Tomoyo Taki Mariko Nakamoto Emi Shuto
出版者: 公益社団法人日本薬学会
雑誌: Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日: vol.40, no.4, pp.391-395, 2017-04-01 (Released:2017-04-01)
参考文献数: 27
被引用文献数: 16

Propolis is a bee product with various biological properties. C57BL/6 mice were fed a high-fat diet and treated with propolis for 14 weeks. Body weight in mice treated with 2% propolis was less than that in control mice from 3 weeks after the start of treatment until 14 weeks except for the 7th week. Mice treated with propolis showed significantly lower epididymal fat weight and subcutaneous fat weight. Infiltration of epididymal fat by macrophages and T cells was reduced in the propolis group. Supplementation of propolis increased feces weight and fat content in feces, suggesting that mechanisms of weight reduction by propolis partly include a laxative effect and inhibition of fat absorption.

2017-04-12 08:12:02
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1 0 0 0 OA Vitamin A Deficiency Impairs Induction of Oral Tolerance in Mice

著者: Akiko NAKAMOTO Emi SHUTO Rie TSUTSUMI Mariko NAKAMOTO Yoshitaka NII Tohru SAKAI
出版者: Center for Academic Publications Japan
雑誌: Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日: vol.61, no.2, pp.147-153, 2015 (Released:2015-06-08)
参考文献数: 38
被引用文献数: 2 10

Oral tolerance is a phenomenon of induction of systemic unresponsiveness to antigens ingested by the oral route and loss of immune response. Studies have shown the importance of vitamin A in oral tolerance in vitro but not in an in vivo experimental model. Therefore, we carried out experiments to determine how vitamin A deficiency affects tolerance induction and the ability of mesenteric lymph node (MLN) CD11c+ cells to induce regulatory T cells (Tregs). Immunological tolerance was induced by oral ovalbumin (OVA) administration in vitamin A-sufficient mice. OVA-specific antibody and cytokine production were significantly reduced. On the other hand, in vitamin A-deficient mice, both OVA-specific antibody and cytokine production were not suppressed by oral OVA administration. Regarding induction of Tregs, the conversion rate of Foxp3+ cells from naïve CD4+ cell by CD11c+ cells was decreased in vitamin A-deficient mice. Our study indicates that vitamin A deficiency causes the breakdown of oral tolerance in vivo.

2015-06-12 23:00:41
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1 0 0 0 OA Consumption of Seafood, Serum Liver Enzymes, and Blood Levels of PFOS and PFOA in the Japanese Population

著者: Miwa Yamaguchi Kokichi Arisawa Hirokazu Uemura Sakurako Katsuura-Kamano Hidenobu Takami Fusakazu Sawachika Mariko Nakamoto Tomoya Juta Eisaku Toda Kei Mori Manabu Hasegawa Masaharu Tanto Masayuki Shima Yoshio Sumiyoshi Kenji Morinaga Kazunori Kodama Takaichiro Suzuki Masaki Nagai Hiroshi Satoh
出版者: (公社)日本産業衛生学会
雑誌: Journal of Occupational Health (ISSN:13419145)
巻号頁・発行日: pp.12-0264-OA, (Released:2013-04-09)
被引用文献数: 11 54

Objective: Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) have been shown to accumulate in the human body. The purpose of the present study was to examine the factors associated with the blood levels of PFOS and PFOA. Methods: A cross-sectional study was performed on 307 men and 301 women (aged 16-76 years) living in 15 prefectures in Japan. Blood levels of PFOS and PFOA were measured by liquid chromatography-mass spectrometry. Hepatic enzymes (γ-GTP, GOT, and GPT) and ω-3 polyunsaturated fatty acids (DHA and EPA) levels in serum were also measured. Associations between the levels of PFOS and PFOA in blood and the intake frequency of 41 kinds of dishes, foods and beverages and the serum levels of liver enzymes and ω-3 polyunsaturated fatty acids were examined using rank correlations. Results: Frequency of intake of boiled fish in broth, sliced raw fish and coastal fish showed significant positive correlations with PFOS concentrations in blood after adjustments for potential confounders. Serum levels of GOT, GPT, DHA and EPA showed significant positive correlations with PFOS and PFOA in blood. There was also a significant regional difference in the blood levels of PFOS and PFOA, with medians being highest in the Tokai/Hokuriku/Kinki region. Conclusion: These findings suggest that the concentrations of PFOS in blood were mainly associated with fish consumption and that the levels of PFOS and PFOA were mainly associated with the serum levels of liver enzymes in Japanese populations. Further investigations are required to clarify the reason for the regional differences in blood levels of PFOS and PFOA in Japan.

2013-04-12 22:21:42
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