著者
Ryosuke Taniguchi Juno Deguchi Takuya Hashimoto Osamu Sato
出版者
The Editorial Committee of Annals of Vascular Diseases
雑誌
Annals of Vascular Diseases (ISSN:1881641X)
巻号頁・発行日
pp.oa.18-00167, (Released:2019-05-08)
参考文献数
25
被引用文献数
13

Objective: Open revascularization of the lower extremity in patients with chronic limb-threatening ischemia (CLTI) does not guarantee limb salvage. Due to the high prevalence of frailty among these patients, we hypothesized that sarcopenia negatively affects limb prognosis.Methods: Seventy-five CLTI patients who underwent open revascularization between 2011 and 2015 were retrospectively reviewed. The lumbar psoas index, which is the ratio of the cross-sectional area of the psoas major muscles to the patients’ height squared, was used as a surrogate marker for sarcopenia. Male and female patients were stratified separately according to lumbar psoas index values. The lower two-thirds of the population for each sex were defined as the sarcopenia group, with the higher third defined as the non-sarcopenia group.Results: Comorbidities and ambulatory status did not differ between the sarcopenia (n=50) and non-sarcopenia (n=25) groups. The sarcopenia group had significantly lower overall survival rates than the non-sarcopenia group (60% vs 87% at 3 years, P<0.05). Moreover, the limb salvage rates were significantly lower in the sarcopenia group than in the non-sarcopenia group (73% vs 100% at 2 years, P<0.05).Conclusion: Sarcopenia, as measured by the lumbar psoas index, may predict poor limb prognosis in CLTI patients undergoing open revascularization.
著者
Mitsunori MATSUMAE Osamu SATO Akihiro HIRAYAMA Naokazu HAYASHI Ken TAKIZAWA Hideki ATSUMI Takatoshi SORIMACHI
出版者
The Japan Neurosurgical Society
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
vol.56, no.7, pp.416-441, 2016 (Released:2016-07-15)
参考文献数
310
被引用文献数
29 56

Cerebrospinal fluid (CSF) plays an essential role in maintaining the homeostasis of the central nervous system. The functions of CSF include: (1) buoyancy of the brain, spinal cord, and nerves; (2) volume adjustment in the cranial cavity; (3) nutrient transport; (4) protein or peptide transport; (5) brain volume regulation through osmoregulation; (6) buffering effect against external forces; (7) signal transduction; (8) drug transport; (9) immune system control; (10) elimination of metabolites and unnecessary substances; and finally (11) cooling of heat generated by neural activity. For CSF to fully mediate these functions, fluid-like movement in the ventricles and subarachnoid space is necessary. Furthermore, the relationship between the behaviors of CSF and interstitial fluid in the brain and spinal cord is important. In this review, we will present classical studies on CSF circulation from its discovery over 2,000 years ago, and will subsequently introduce functions that were recently discovered such as CSF production and absorption, water molecule movement in the interstitial space, exchange between interstitial fluid and CSF, and drainage of CSF and interstitial fluid into both the venous and the lymphatic systems. Finally, we will summarize future challenges in research. This review includes articles published up to February 2016.
著者
Mitsunori MATSUMAE Osamu SATO Akihiro HIRAYAMA Naokazu HAYASHI Ken TAKIZAWA Hideki ATSUMI Takatoshi SORIMACHI
出版者
社団法人 日本脳神経外科学会
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
pp.ra.2016-0020, (Released:2016-05-27)
参考文献数
310
被引用文献数
2 56

Cerebrospinal fluid (CSF) plays an essential role in maintaining the homeostasis of the central nervous system. The functions of CSF include: (1) buoyancy of the brain, spinal cord, and nerves; (2) volume adjustment in the cranial cavity; (3) nutrient transport; (4) protein or peptide transport; (5) brain volume regulation through osmoregulation; (6) buffering effect against external forces; (7) signal transduction; (8) drug transport; (9) immune system control; (10) elimination of metabolites and unnecessary substances; and finally (11) cooling of heat generated by neural activity. For CSF to fully mediate these functions, fluid-like movement in the ventricles and subarachnoid space is necessary. Furthermore, the relationship between the behaviors of CSF and interstitial fluid in the brain and spinal cord is important. In this review, we will present classical studies on CSF circulation from its discovery over 2,000 years ago, and will subsequently introduce functions that were recently discovered such as CSF production and absorption, water molecule movement in the interstitial space, exchange between interstitial fluid and CSF, and drainage of CSF and interstitial fluid into both the venous and the lymphatic systems. Finally, we will summarize future challenges in research. This review includes articles published up to February 2016.
著者
松浦 とも子 佐藤 修 Tomoko MATSUURA Osamu SATO
出版者
国際交流基金
雑誌
国際交流基金日本語教育紀要 = The Japan Foundation Japanese-Language Education Bulletin (ISSN:13495658)
巻号頁・発行日
no.8, pp.71-86, 2012-03-01

本稿では、教師研修ポートフォリオの導入を検討するため、中国における大学日本語教師のポートフォリオに対する認識を、インタビュー結果とアンケート記述をSCATの手法により分析することで明らかにした。教師たちは、ポートフォリオについて理解する前には、漠然と振り返りに使えるというイメージを持っているだけであった。しかし講義を受けた後は、ポートフォリオを利用して「学びのプロセスの可視化」、「時間軸の中で学習を捉える」、「学習者と教師とのコミュニケーション」、「仲間のポートフォリオとの比較検討」などが可能であるというように、ポートフォリオに対する期待が示された。同時に、利用方法について不安があることが確認された。また、教師研修での学びはそれを現場でどう生かせるかという視点で評価されるべきだと教師たちが考えていることもわかった。This paper clarifies the image of Portfolio among university teachers in China in order to introduce portfolio assessment in a teacher training course. The authors analyzed the result of an interview research and a questionnaire survey using SCAT, Steps for Coding and Theorization. Before the training course, the teachers had had a vague idea of Portfolio that it could be used for self-reflection, however, after taking the lecture, they expected the possibility of "visualization of learning process", "recognition of learning in chronological order", "communication between a teacher and a learner", "comparative review of other learner's Portfolio". They also showed an anxiety on how to use the Portfolio at the same time. The authors found that the teachers thought what one had learned in a teacher training course should be evaluated from the perspective of how one can use it in his classroom.