著者

Zhiqiang Wang Xin Liu Zhiqiang Li Xiaosong Wang Minghua Wang Quan Li Yan Li Yu Liu

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Electronics Express (ISSN:13492543)

巻号頁・発行日

vol.19, no.23, pp.20210286, 2022-12-10 (Released:2022-12-10)

参考文献数

35

被引用文献数

1

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This paper presents a four-way current-combining Ka-band power amplifier (PA) in 65-nm CMOS technology. A symmetrical, transmission line based four-way current combiner, together with output transformers, is used to transfer the high load impedance (4*ZL) to the desired Zopt for each power unit cell. Besides, both interstage/input flexible matching transformers and the power splitter are optimized to improve the performance. Based on the methodology mentioned above, the power amplifier demonstrates a small-signal gain of about 24.12 dB, a saturated output power of 21.56 dBm, and a peak power-added efficiency of 27.3% at 35GHz.

著者

Yicong Ye Xiliang Zhao Chenchen Tu Quan Li Yong Zeng

出版者

International Heart Journal Association

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

pp.20-285, (Released:2020-10-28)

参考文献数

31

被引用文献数

1

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The elevated serum levels of alkaline phosphatase (ALP) serve as independent predictors of stent thrombosis after percutaneous coronary intervention (PCI). Our study aims at investigating the relationship between the serum ALP and the responsiveness to clopidogrel. Patients undergoing elective PCI were enrolled for the study, and all participants received a 300-mg clopidogrel loading dose. The responsiveness to clopidogrel was determined by thromboelastography (TEG), and low responsiveness to clopidogrel was defined based on two aspects: (1) adenosine diphosphate (ADP) -induced platelet-fibrin clot strength (MAADP) of > 47 mm and (2) ADP-induced platelet inhibition rate of < 50%. A logistic regression model analysis was used to calculate the risks of responsiveness to clopidogrel as odd ratios (OR) and 95% confidence intervals (CIs). Overall, 809 patients were considered for the study. They were divided into four quartile groups based on the serum ALP levels. A positive linear trend was observed in MAADP across the ALP quartiles (P for linear trend < 0.001), whereas ADP-induced platelet inhibition rate decreased across the ALP quartiles (P for linear trend = 0.007). When multiple confounders were adjusted, the highest ALP quartile correlated with an increased risk of low responsiveness to clopidogrel compared to the lowest ALP quartile (OR, 1.423; 95% CI, 1.017-1.991; P = 0.039). In the sensitivity analysis, the association remained significant for different definitions of low responsiveness to clopidogrel. The elevated serum levels of ALP are independently associated with an increased risk of low responsiveness to clopidogrel.