著者

Katsuya Ohkawa Natsumi Ogata Akane Shibasaki Takahisa Tanaka Ryo Itabashi Chie Kouno Takanori Saito Hitoshi Ohara Satoru Kondo

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.QH-064, (Released:2023-08-11)

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To elucidate the inhibitory effect of ethephon on the occurrence of water-soaked disorder in Japanese pear ‘Akizuki’ (Pyrus pyrifolia Nakai) fruit, we sprayed fruits with 100 mg·L−1 ethephon solution approximately 120 DAFB in the 2012, 2014, 2015, 2016, and 2017 seasons. Ethephon treatment reduced the incidence and degree of water-soaked disorder at commercial harvest time. There was no significant difference in fruit size or soluble solids content between the ethephon-treated fruits and the control fruits, except for fruit size in the 2012 season. During the nine-day storage period after harvest, water-soaked disorder did not develop in either the ethephon-treated fruits or the control fruits. In addition, flesh firmness and soluble solids content did not differ between the ethephon-treated fruits and the control fruits during the storage period. Ethylene production increased sharply in the ethephon-treated fruits a few days after the ethephon treatment, in contrast to the control fruits. Sucrose content in the ethephon-treated fruits was higher than that in the control fruits on day 10 after treatment. Sorbitol content in the ethephon-treated fruits was lower than that in the control fruits on days 10 and 20 after treatment. Water-soluble, Na2CO3-soluble, and total pectin contents were not affected by the ethephon treatment. Hemicellulose, cellulose, and starch contents in the ethephon-treated fruits decreased earlier than those in the control fruits. Sucrose content was lower, but sorbitol and glucose contents were higher, in water-soaked tissue than in sound tissue. These results suggest that ethephon treatment rapidly induces changes in the contents of fruit’s internal components and accelerates fruit maturation, thereby alleviating factors that cause water-soaked disorder in ‘Akizuki’.

著者

Kazumasa Oura Takashi Yamaguchi Taro Suzuki Mao Yamaguchi Oura Ryo Itabashi Tetsuya Maeda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.9316-22, (Released:2022-08-10)

参考文献数

15

被引用文献数

1

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Several case reports of patients with both moyamoya syndrome (MMS) and antiphospholipid syndrome (APS) have been published. However, the relationship between MMS and APS has not been clarified. We herein report a patient with MMS who had an ischemic stroke with rapid worsening of stenosis of the middle cerebral artery associated with APS. The patient was triple-positive for antiphospholipid antibodies. Patients with MMS complicated by APS should be closely followed up with vascular imaging.

著者

Kazumasa Oura Keita Taguchi Mao Yamaguchi Oura Ryo Itabashi Tetsuya Maeda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.7735-21, (Released:2021-07-30)

参考文献数

30

被引用文献数

3

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Takayasu's arteritis is an inflammatory disease of unknown etiology that causes stenosis, occlusion, or dilatation of the aorta and its major branches, the pulmonary arteries, and the coronary arteries. The incidence of extracranial carotid artery aneurysm in patients with Takayasu's arteritis is reportedly 1.8%-3.9%. We herein report a patient with Takayasu's arteritis who presented with transient left hemiplegia immediately after neck massage. Carotid ultrasonography revealed a thrombus within the fusiform aneurysm on the right common carotid artery. We speculated that fragmentation from the intra-aneurysmal thrombus was caused by neck massage.

著者

Ryo Itabashi Yuya Shigehatake Takuya Saito Kaoru Endo Kazuki Fukuma Yuya Kobayashi Yuichi Kawabata Yukako Yazawa Yasushi Matsumoto Manabu Inoue Masatoshi Koga

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.62, no.5, pp.703-710, 2023-03-01 (Released:2023-03-01)

参考文献数

24

被引用文献数

1

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Objectives This study clarified the usefulness of carotid duplex ultrasound (CDU) in evaluating large vessel occlusion (LVO) in patients with acute stroke planned to be treated with mechanical thrombectomy (MT). Methods This study was single-center, prospective, observational trial. If the ratio of end-diastolic velocity in the common carotid arteries was ≥1.4, or diastolic flow in the affected internal carotid artery (ICA) was absent on CDU, patients were immediately transferred to the angio-suite without additional cerebrovascular imaging. Clinical parameters, including time metrics and outcomes, were evaluated in participants. Patients We enrolled stroke patients with a National Institutes of Health Stroke Scale score ≥6 and Alberta Stroke Program Early CT score ≥6 in whom MT could be initiated within 6 hours of the stroke onset. Results Among 140 patients screened during the study period, 48 were ultimately enrolled. Twenty-seven patients were diagnosed with LVO by CDU alone. CDU offered 83% sensitivity and 82% specificity for identifying the occlusion of the ICA or M1 segment of the middle cerebral artery. Among the 29 total patients treated with MT, 20 (67%) showed a modified Rankin Scale score ≤2 at 90 days. The door-to-puncture time was significantly shorter in patients evaluated by CDU alone (34 minutes) than in those evaluated by magnetic resonance angiography after CDU (47.5 minutes, p<0.001). Conclusion CDU might reduce the time metrics for early initiation of MT with good sensitivity and specificity in identifying LVO.

著者

Kazumasa Oura Mitsunobu Sato Mao Yamaguchi Oura Ryo Itabashi Tetsuya Maeda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.8931-21, (Released:2022-02-01)

参考文献数

18

被引用文献数

1

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Spontaneous dissection of the brachiocephalic artery is rare, and there is insufficient evidence for optimal treatment. We herein report a case of ischemic stroke due to spontaneous dissection of the brachiocephalic to the right common carotid artery. The patient was treated medically but died suddenly 18 days after the onset because of aortic dissection. Although almost all reported cases of spontaneous dissection of the brachiocephalic artery have had good outcomes with medical management, it is important to note that sudden development of aortic dissection might occur, even without initial findings suggestive of this condition.

著者

Sohei Yoshimura Masatoshi Koga Shoichiro Sato Kenichi Todo Hiroshi Yamagami Masaya Kumamoto Ryo Itabashi Tadashi Terasaki Kazumi Kimura Yoshiki Yagita Yoshiaki Shiokawa Kenji Kamiyama Satoshi Okuda Yasushi Okada Shunya Takizawa Yasuhiro Hasegawa Tomoaki Kameda Satoshi Shibuya Yoshinari Nagakane Yasuhiro Ito Hideki Matsuoka Kazuhiro Takamatsu Kazutoshi Nishiyama Kyohei Fujita Teppei Kamimura Daisuke Ando Toshihiro Ide Takeshi Yoshimoto Masayuki Shiozawa Soichiro Matsubara Yoshitaka Yamaguchi Naoto Kinoshita Takayuki Matsuki Junji Takasugi Keisuke Tokunaga Kyoko Higashida Kazunari Homma Kazuomi Kario Shoji Arihiro Kazunori Toyoda for the SAMURAI Study Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-18-0067, (Released:2018-06-01)

参考文献数

27

被引用文献数

34

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Background:We determined the 2-year long-term risk-benefit profile in patients with stroke or transient ischemic attack (TIA) receiving warfarin or direct oral anticoagulants (DOACs) for nonvalvular atrial fibrillation (NVAF) using a prospective, multicenter, observational registry in Japan.Methods and Results:NVAF patients within 7 days after onset of ischemic stroke/TIA were enrolled in 18 stroke centers. Outcome measures included ischemic and bleeding events and death in the 2-year follow-up period. We enrolled 1,116 patients taking either warfarin (650 patients) or DOACs (466 patients) at acute hospital discharge. DOAC users were younger and had lower National Institutes of Health Stroke Scale, CHADS2and discharge modified Rankin Scale scores than warfarin users (P<0.0001 each). Incidences of stroke/systemic embolism (adjusted hazard ratio, 1.07; 95% CI, 0.66–1.72), all ischemic events (1.13; 0.72–1.75), and ischemic stroke/TIA (1.58; 0.95–2.62) were similar between groups. Risks of intracranial hemorrhage (0.32; 0.09–0.97) and death (0.41; 0.26–0.63) were significantly lower for DOAC users. Infection was the leading cause of death, accounting for 40% of deaths among warfarin users.Conclusions:Stroke/TIA patients receiving DOACs for secondary prevention were younger and had lower stroke severity and risk indices than those receiving warfarin. Estimated cumulative incidences of stroke and systemic embolism within 2 years were similar between warfarin and DOACs users, but those of death and intracranial hemorrhage were significantly lower among DOAC users.