著者
Tatsuya Nishikawa Takeshi Fujita Toshitaka Morishima Sumiyo Okawa Terutaka Hino Taku Yasui Wataru Shioyama Toru Oka Isao Miyashiro Masashi Fujita
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-20-1160, (Released:2021-02-17)
参考文献数
25
被引用文献数
9

Background:The effect of incidental pulmonary embolism (PE) on long-term prognosis in cancer patients is unclear. This study assessed the characteristics of cancer and venous thromboembolism (VTE) and the effect of incidental PE identified by oncologists on long-term survival of patients with cancer.Methods and Results:This single-center, retrospective, cohort study used hospital-based cancer registry data from the Osaka International Cancer Institute linked with electronic medical records and administrative data from Japan’s Diagnosis Procedure Combination Per-diem Payment System. Overall, 15,689 cancer patients underwent contrast-enhanced thoracic computed tomography during 2010–2018. After excluding patients with missing data, symptomatic patients, or patients with suspected PE, 174 with incidental PE (PE+ group) and 13,197 with no PE (PE− group) were identified. The total incidence of incidental PE was 1.3%. No deaths from thrombotic events were identified in the PE+ group. Both groups were adjusted for cancer- and VTE-related characteristics using inverse probability weighting. After adjusting for immortal time bias in the PE+ group, Kaplan-Meier analysis revealed that all-cause mortality was higher in the PE+ group (hazard ratio, 2.26; 95% confidence interval, 1.53–3.33). A Cox proportional hazard model revealed that metastatic cancer and a history of curative treatment were significant prognostic factors, whereas central PE and residual proximal deep vein thrombosis were not.Conclusions:Incidental PE in cancer patients indicates poorer prognosis. Cancer-related but not thrombosis-related factors determine prognosis.
著者
Sheila Gamut OYAO Takeshi FUJITA
出版者
Japan Society for Science Education
雑誌
科学教育研究 (ISSN:03864553)
巻号頁・発行日
vol.33, no.3, pp.179-191, 2009-09-10 (Released:2017-06-30)
参考文献数
32

This study explores the beliefs and practices of Japanese and Filipino elementary teachers concerning their roles and those of their pupils in the conduct of hands-on science, as well as barriers to hands-on science teaching. A survey questionnaire was used to achieve the aims of this study. The results indicate that Japanese and Filipino teachers had beliefs and actual practices regarding hands-on science that can be described as having their pupils design the method of investigation, and work collaboratively. Nevertheless, Filipino teachers have the tendency to provide their pupils with the solutions to the problems. The findings also show that in both countries teachers had experienced major problems relating to laboratory apparatus, science materials and length of class period in their actual teaching. Additionally, Japanese teachers had experienced other big problems pertaining to planning time and limited background and experience in the use of science materials, whereas Filipino teachers felt that the large class size was another big problem. The results further corroborate previous qualitative findings that indicate associations between teachers' beliefs and practices.