著者

Yuki Shimizu Shigeo Morimoto Masayuki Sanada Yukinori Inoue

出版者

The Institute of Electrical Engineers of Japan

雑誌

IEEJ Journal of Industry Applications (ISSN:21871094)

巻号頁・発行日

vol.10, no.5, pp.554-563, 2021-09-01 (Released:2021-09-01)

参考文献数

19

被引用文献数

7

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Interior permanent magnet synchronous motors (IPMSMs) have been widely used as traction motors in electric vehicles. Finite element analysis is commonly used to design IPMSMs but is highly time-intensive. To shorten the design period for IPMSMs, various surrogate models have been constructed to predict relevant characteristics, and they have been used in the optimization of IPMSM geometry. However, to date, no surrogate models have been able to accurately predict the characteristics over the wide speed range required for automotive applications. Herein, we propose a method for accurately predicting the speed-torque characteristics of an IPMSM by using machine learning techniques. To improve the prediction accuracy, we set the motor parameters as the prediction target of the machine learning methods. We then used the trained surrogate model and a real-coded genetic algorithm to minimize the volume of the permanent magnet and showed that the design time can be significantly reduced compared with the case where only finite element analysis is used.

著者

Akira MATSUDA Ikki MITSUI Yuki SHIMIZU Teppei KANDA Akihiro OHNISHI Masahiro MIYABE Yoshiki ITOH

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.20-0179, (Released:2020-09-11)

被引用文献数

1

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Little is known about the pathological roles of sebaceous glands in canine skin diseases, as most examinations have been conducted with cultured human sebaceous epithelial cell lines. To our knowledge, there is no available canine sebaceous epithelial cell line. The purpose of this study was to establish a canine sebaceous epithelial cell line and characterize it. An eyelid mass in a dog was surgically resected for treatment, and it was histologically diagnosed as sebaceous epithelioma. Collected tissue was conducted for culture, and the growing epithelial-like cells were passaged. The cells showed continuous proliferation for over 6 months. After 40 passages, the cells were named CMG-1. Lipid droplets in the cytoplasm of CMG-1 cells were confirmed by Oil Red O staining. As reported in studies with human sebaceous epithelial cell lines, lipogenesis in CMG-1 cells was promoted by linoleic acid, whereas TGF-β suppressed it. Additionally, real-time PCR revealed that the expression levels of chemokines and cytokines, including CCL-2, CCL-20, CXCL-10, TNF-α, IL-1α, IL-1β, and IL-8, were significantly increased in CMG-1 cells following treatment with lipopolysaccharide. In conclusion, we successfully established a new canine sebaceous epithelial cell line. Our data indicated that lipogenesis and inflammatory responses were quantitatively evaluable in this cell line. CMG-1 cells could be useful for the pathological analysis of sebaceous gland diseases in dogs.

著者

Kenji KUTARA Noritaka MAETA Teppei KANDA Akihiro OHNISHI Ikki MITSUI Masahiro MIYABE Yuki SHIMIZU Yasuhiko OKAMURA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.19-0260, (Released:2019-09-04)

被引用文献数

3

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An 11-year-old male Miniature Dachshund was referred for acute neurological deficits in the pelvic limbs. T2-weighted magnetic resonance imaging revealed that the spinal cord at the L1-2 intervertebral disc space was heterogeneously hyperintense in the sagittal plane and was mildly compressed from the ventral side by a small hypointense mass in the transverse plane. However, the lesion showed mass enhancement and severe spinal cord compression on post-contrast T1-weighted imaging. On three-dimensional myelography, a “golf tee sign” was observed around the mass. Therefore, we diagnosed an intradural extramedullary lesion. The mass was surgically removed and histologically diagnosed as a hemangiosarcoma. The “golf tee sign” observed on magnetic resonance myelography may be useful for distinguishing intradural extramedullary masses from intramedullary masses.

著者

Suzuka Sasayama Yuki Shimizu Shigeo Morimoto Yukinori Inoue Masayuki Sanada

出版者

The Institute of Electrical Engineers of Japan

雑誌

IEEJ Journal of Industry Applications (ISSN:21871094)

巻号頁・発行日

pp.22007240, (Released:2023-01-13)

被引用文献数

1

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Interior permanent magnet synchronous motors (IPMSMs) are used for various applications and high efficiency control is required. Maximum torque per ampere (MTPA) control is a method to control IPMSMs with high efficiency. However, since the motor parameters vary with magnetic saturation, MTPA control cannot be easily realized. Here in, we propose a fully online and automatic MTPA control method. To find the MTPA point while driving the motor, it is necessary to predict the entire flux linkage surface. Therefore, the flux linkage surface is approximated by a plane from the sensor information at a specific current condition that considers the effect of magnetic cross-saturation. MTPA control is achieved using the estimated flux linkage plane and the gradient ascent method. The simulation results reveal that the torque maximized in two search periods, which was completed in 0.06 s. The proposed method is effective for a wide current range.

著者

Yuki Shimizu Shigeo Morimoto Masayuki Sanada Yukinori Inoue

出版者

The Institute of Electrical Engineers of Japan

雑誌

IEEJ Journal of Industry Applications (ISSN:21871094)

巻号頁・発行日

vol.6, no.6, pp.401-408, 2017-11-01 (Released:2017-11-01)

参考文献数

11

被引用文献数

4 22

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Nowadays, interior permanent magnet synchronous motors (IPMSMs) are widely utilized as traction motors. The permanent magnets used in IPMSMs are an important factor; thus, high-coercivity permanent magnets with lesser rare-earth elements are in development. This study investigated the performance of IPMSMs typically used in automotive applications modified to contain a strong magnet model (SMM). Rotor models with two permanent magnet arrangements, that is, a V-shaped single-layered permanent magnet structure (Type 1V) and a double-layered permanent magnet structure (Type 2D), were considered in this study. This paper discusses the characteristics of the analysis models based on the results of a two-dimensional finite element analysis. The maximum torques of Types 1V and 2D with the SMMs were approximately the same. In addition, the loss of Type 2D with the SMM was lower than that of Type 1V with the SMM at two evaluation points and under two driving schedules. Therefore, Type 2D was proved to be suitable for use with the SMM.

著者

Akira MATSUDA Ikki MITSUI Yuki SHIMIZU Teppei KANDA Akihiro OHNISHI Masahiro MIYABE Yoshiki ITOH

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.82, no.11, pp.1577-1584, 2020 (Released:2020-11-12)

参考文献数

42

被引用文献数

1

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Little is known about the pathological roles of sebaceous glands in canine skin diseases, as most examinations have been conducted with cultured human sebaceous epithelial cell lines. To our knowledge, there is no available canine sebaceous epithelial cell line. The purpose of this study was to establish a canine sebaceous epithelial cell line and characterize it. An eyelid mass in a dog was surgically resected for treatment, and it was histologically diagnosed as sebaceous epithelioma. Collected tissue was conducted for culture, and the growing epithelial-like cells were passaged. The cells showed continuous proliferation for over 6 months. After 40 passages, the cells were named CMG-1. Lipid droplets in the cytoplasm of CMG-1 cells were confirmed by Oil Red O staining. As reported in studies with human sebaceous epithelial cell lines, lipogenesis in CMG-1 cells was promoted by linoleic acid, whereas transforming growth factor-β (TGF-β) suppressed it. Additionally, real-time PCR revealed that the expression levels of chemokines and cytokines, including CC chemokine ligand (CCL)-2, CCL-20, CXCL-10, Tumor necrosis factor-α (TNF-α), Interleukin (IL)-1α, IL-1β, and IL-8, were significantly increased in CMG-1 cells following treatment with lipopolysaccharide. In conclusion, we successfully established a new canine sebaceous epithelial cell line. Our data indicated that lipogenesis and inflammatory responses were quantitatively evaluable in this cell line. CMG-1 cells could be useful for the pathological analysis of sebaceous gland diseases in dogs.

著者

Hiroyuki Koyama Satoshi Yasuda Shota Kakoi Yasuhisa Ohata Yuki Shimizu Chie Hasegawa Akiko Hayakawa Tomoyuki Akiyama Takashi Yagi Daisuke Aotani Kenro Imaeda Keiichi Ozono Hiromi Kataoka Tomohiro Tanaka

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.3298-19, (Released:2019-11-29)

参考文献数

24

被引用文献数

8

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A 40-year-old Japanese woman presented to our hospital with general fatigue and muscle weakness. She had a history of premature loss of deciduous teeth at 4 years old, her serum alkaline phosphatase (ALP) activity was as low as 91 U/L, and radiologic studies revealed thoracic deformity and sacroiliac calcification. Genetic sequencing revealed a heterozygous c.1559delT mutation in the tissue non-specific alkaline phosphatase gene (ALPL). Based on these findings, she was diagnosed with hypophosphatasia (HPP), and treatment with asfotase alfa, a recombinant human tissue-nonspecific alkaline phosphatase (TNSALP), was initiated. After six months of treatment with asfotase alfa, improvements were observed in the SF-36 score, six-minute walk distance, and grasping power. Although the overdiagnosis needs to be avoided, HPP should be considered in patients with undiagnosed musculoskeletal symptoms and a low serum ALP activity.

著者

Kenichiro TODOROKI Yuto KUDOH Misuzu NAKAMURA Yuki SHIMIZU Takamitsu SASAKI Hideyuki OTSUKI Keisuke WADA Jun Zhe MIN Hajime MIZUNO Kouichi YOSHINARI Toshimasa TOYO’OKA

出版者

The Japan Society for Analytical Chemistry

雑誌

Analytical Sciences (ISSN:09106340)

巻号頁・発行日

pp.18SCP05, (Released:2018-07-20)

被引用文献数

6

著者

Norio KONNO Yuki SHIMIZU Masato TAKEI

出版者

東北大学大学院情報科学研究科ジャーナル編集委員会

雑誌

Interdisciplinary Information Sciences (ISSN:13409050)

巻号頁・発行日

vol.23, no.1, pp.1-8, 2017 (Released:2017-03-31)

参考文献数

17

被引用文献数

5

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The present paper treats the period TN of the Hadamard walk on a cycle CN with N vertices. Dukes (2014) considered the periodicity of more general quantum walks on CN and showed T2=2, T4=8, T8=24 for the Hadamard walk case. We prove that the Hadamard walk does not have any period except for his case, i.e., N = 2,4,8. Our method is based on a path counting and cyclotomic polynomials which is different from his approach based on the property of eigenvalues for unitary matrix that determines the evolution of the walk.