著者

Takayuki Hishiki Kengo Usui Tadaichi An Rieko Suzuki Jun-ichi Sakuragi Yuki Tanaka Yu Matsuki Jun Kawai Yasushi Kogo Yoshihide Hayashizaki Tomohiko Takasaki

出版者

National Institute of Infectious Diseases

雑誌

Japanese Journal of Infectious Diseases (ISSN:13446304)

巻号頁・発行日

vol.75, no.3, pp.277-280, 2022-05-31 (Released:2022-05-24)

参考文献数

21

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019. Despite the recent introduction of vaccines against SARS-CoV-2, more effective vaccines and antiviral drugs must be developed. Here, we isolated five SARS-CoV-2 strains from four patients with coronavirus disease (COVID-19) and an asymptomatic individual using pharyngeal swabs, nasopharyngeal swabs, and sputum samples. Cytopathic effects in inoculated Vero cells were observed between days 3 and 7. SARS-CoV-2 infection was confirmed by quantitative reverse-transcription polymerase chain reaction (RT-qPCR) and next-generation sequencing. Phylogenetic analyses of the whole genome sequences showed that the virus isolates from the clinical samples belonged to the Wuhan and European lineages. These findings and the isolated viruses may contribute to the development of diagnostic tools, vaccines, and antiviral drugs for COVID-19.

著者

Yuki Tanaka Yutaka Yamaguti

出版者

The Japan Society for Industrial and Applied Mathematics

雑誌

JSIAM Letters (ISSN:18830609)

巻号頁・発行日

vol.15, pp.117-120, 2023 (Released:2023-11-16)

参考文献数

14

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To understand the ability and limitations of convolutional neural networks to generate time series that mimic complex temporal signals, we trained a generative adversarial network consisting of convolutional networks to generate chaotic time series and used nonlinear time series analysis to evaluate the generated time series. A numerical measure of determinism and the Lyapunov exponent showed that the generated time series well reproduce the chaotic properties of the original time series. However, error distribution analyses showed that large errors appeared at a low but non-negligible rate. Such errors would not be expected if the distribution were assumed to be exponential.

著者

Takayuki Hishiki Kengo Usui Tadaichi An Rieko Suzuki Jun-ichi Sakuragi Yuki Tanaka Yu Matsuki Jun Kawai Yasushi Kogo Yoshihide Hayashizaki Tomohiko Takasaki

出版者

National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee

雑誌

Japanese Journal of Infectious Diseases (ISSN:13446304)

巻号頁・発行日

pp.JJID.2021.292, (Released:2021-10-29)

参考文献数

21

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019. Despite the recent introduction of vaccines against SARS-CoV-2, more effective vaccines and antiviral drugs must be developed. Here, we isolated five SARS-CoV-2 strains from four patients with coronavirus disease (COVID-19) and an asymptomatic individual using pharyngeal swabs, nasopharyngeal swabs, and sputum samples. Cytopathic effects in inoculated Vero cells were observed between days 3 and 7. SARS-CoV-2 infection was confirmed by quantitative reverse-transcription polymerase chain reaction (RT-qPCR) and next-generation sequencing. Phylogenetic analyses of the whole genome sequences showed that the virus isolates from the clinical samples were belonged to the Wuhan and European lineages. These findings and isolated viruses may contribute to the development of diagnostic tools, vaccines, and antiviral drugs for COVID-19.

著者

Nobuo Nakada Norimitsu Koga Yuki Tanaka Toshihiro Tsuchiyama Setsuo Takaki Masaharu Ueda

出版者

The Iron and Steel Institute of Japan

雑誌

ISIJ International (ISSN:09151559)

巻号頁・発行日

vol.55, no.9, pp.2036-2038, 2015-09-15 (Released:2015-09-29)

参考文献数

17

被引用文献数

13 18

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The strength of pearlitic steel was clearly reduced by annealing, even though cementite stably maintained a lamellar structure. In response, lattice strain of the ferrite phase in pearlite monotonically decreased with increasing annealing time. As a result, a good linear relationship was established between the strength and ferrite lattice strain independent of the interlamellar spacing and morphology of cementite. This suggests that the ferrite/cementite elastic misfit strain contributes to the high strength of pearlitic steel.

著者

Hitoshi HATAI Katsuhisa NAGAI Yuki TANAKA Noriaki MIYOSHI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.20-0305, (Released:2020-06-22)

被引用文献数

2

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Alveolar rhabdomyosarcoma (ARMS) is a rare mesenchymal tumor with differentiation toward the skeletal muscle. Although several cases of canine ARMS have been reported in veterinary medicine, only one case of abdominal ARMS has been reported in a cow. A 13-month-old, Japanese black heifer was referred for pus-like nasal discharge. On autopsy, an 11 × 7 × 4.5-cm pedunculated mass closed to the left palatine tonsillar sinus that occupied the laryngopharynx. Histopathological and immunohistochemical analyses indicated that the tumor was a typical ARMS. To the best of our knowledge, this has been the first case of primary pharyngeal ARMS in a Japanese black heifer, which is rare among cows. Nonetheless, its characteristics, including site, age and subtype, are identical to those among humans and dogs.

著者

田中 佑樹 タナカ ユウキ Yuki Tanaka

雑誌

21世紀社会デザイン研究 : Rikkyo journal of social design studies

巻号頁・発行日

vol.11, pp.179-187, 2012