著者

Sofwatun NIDA Bryan CHRISTIAN Siska VERAWATI NURMALASARI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.Supplement, pp.S122-S128, 2020 (Released:2021-02-22)

参考文献数

20

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The monitoring of the nutritional status in 2017 showed that the percentage of underweight in West Sumbawa was 20.8%—higher than national (17.8%). In 2016, Pencerah Nusantara, a program that strengthen primary health care through youth empowerment and interprofessional collaboration, encouraged the use of moringa as local food ingredient to improve the nutritional status of children at Poto Tano Health Center, West Sumbawa District. Moringa Program is an innovation program to educate community about nutrition and provide moringa-based foods to improve community nutrition. This program was then implemented not only at one health center but in all sub-districts. Furthermore, BAPPEDA (Local Development Planning Agency) included moringa program to Local Nutrition Action Plans as stipulated in the District Regulation No. 80/2017 about preservation of moringa. This study aims to describe the impact of local regulation on the development of moringa program as one of the solutions to overcome the nutritional problems of children under five. The study uses a case study design on community readiness assessment and is complemented by secondary data collection. The study shows clearly that the regulation is the key factor in strengthening cross-sector partnership and in maximizing efforts to improve community nutrition through the Moringa Program. During the implementation of providing moringa-based foods as a provision of supplementary feeding and complementary feeding at integrates health posts (Posyandu), there was a decrease in cases of underweight in children under five at the Poto Tano Health Center from 21.9% in 2017 to 19.9% in 2018.

著者

Pande Putu JANURAGA Edwina FRISDIANTINY Yessi CROSITA Wahdini HAKIM Doddy IZWARDY Aang SUTRISNA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.Supplement, pp.S436-S442, 2020 (Released:2021-02-22)

参考文献数

39

被引用文献数

1

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Despite the present of national policy support, the prevalence of early breastfeeding initiation in Indonesia are still low. Research has shown that health care workers are the most reliable source for breastfeeding advice, but sadly they were often lacking in capacity. The aim of the study to assess the involvement of civil society organization (CSO) and its associated factors in facilitating the implementation of Ten Steps for Successful Breastfeeding (TSSB) based on health care workers’ perspectives in Malang and Sidoarjo districts, East Java Province, Indonesia. We used qualitative approach to in-depth interview 117 participants and conducted 14 FGDs in Sidoarjo and Malang East Java. the PARiHS framework was used to identify the role of CSO in facilitating the BFHI implementation from the health workers perspective to offer insight on the facilitation process and development of future recommendations. The study found that the health care workers’ have good knowledge on the benefits of breastfeeding with significant portion of the knowledge that they hold are coming from trainings provided by the CSO. There was cultural context barriers within the community, where grandmothers are considered as an important influence factor esspecially for working mothers. The implementation of training by the CSO was considered appropriate due to its ability to address some pressing structural obstacles and provide not only training to improve evidence but also help in addressing other contextual barriers. The CSO has offered opportunities not only for dissemination of evidence-based intervention but also to close gaps on resources provision to attend courses.

著者

Hsing-Chun LIN Chiung-Huei PENG Chien-Ning HUANG Jeng-Yuan CHIOU

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.64, no.5, pp.335-339, 2018-10-31 (Released:2018-10-31)

参考文献数

27

被引用文献数

1 8

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Cognitive impairment is a common neurodegenerative disease in the elderly. Dietary factors have an important role in cognitive dysfunction. Soy has many benefits, and consumption of soy-based foods is general in East Asian countries. In this study, we want to investigate the association between cognitive function decline and soy-based food intake among the elderly in Taiwan. This cross-sectional study was based on data obtained from the 2005-2008 Nutrition and Health Survey in Taiwan (NAHSIT). Subjects aged less than 65 y or with missing data were excluded. There was a total of 1,105 participants aged 65 and over who completed Short Portable Mental Status Questionnaire (SPMSQ). Eighty-five-point-six percent of participants consumed soy-based foods every day. After adjustment for potential variables, the logistic regression model showed significant associations for age, gender, education, soy-based foods intake and physical component summary (PCS). Age and female gender were both positively correlated with cognitive impairment (odds ratios: 1.1 and 4.43, respectively). Furthermore, there were negative correlations for education, soy-based foods intake and PCS (odds ratios: 0.25, 0.45 and 0.97, respectively). In this study, we found that soy-based foods were negatively associated with cognitive function decline among Taiwanese elderly. This result may be used as a reference for dietary advice for the elderly.

著者

Osamu EZAKI Mayumi TAKAHASHI Takashi SHIGEMATSU Kyoko SHIMAMURA Junji KIMURA Haruo EZAKI Takahiko GOTOH

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.45, no.6, pp.759-772, 1999 (Released:2009-04-28)

参考文献数

30

被引用文献数

48 61

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Although important roles of dietary n-3 fatty acids in the prevention of coronary heart disease (CHD) have been suggested, long-term effects of dietary α-linolenic acid (ALA, 18:3n-3) have not yet been established under controlled conditions. We tested whether a moderate increase of dietary ALA affects fatty acids composition in serum and the risk factors of CHD. Oxidized LDL (OxLDL) was directly measured by ELISA using antibody specific to OxLDL. By merely replacing soybean cooking oil (SO) with perilla oil (PO) (i.e., increasing 3g/d of ALA), the n-6/n-3 ratio in the diet was changed from 4:1 to 1:1. Twenty Japanese elderly subjects were initially given a SO diet for at least 6 mo (baseline period), a PO diet for 10 mo (intervention period), and then returned to the previous SO diet (washout period). ALA in the total serum lipid increased from 0.8 to 1.6% after 3 mo on the PO diet, but EPA and DHA increased in a later time, at 10 mo after the PO diet, from 2.5 to 3.6% and 5.3 to 6.4%, respectively (p<0.05), and then returned to baseline in the washout period. In spite of increases of serum n-3 fatty acids, the OxLDL concentration did not change significantly when given the PO diet. Body weight, total serum cholesterol, triacylglycerol, glucose, insulin and HbA1c concentrations, platelet count and aggregation function, prothrombin time, partial thromboplastin time, fibrinogen and PAT-1 concentration, and other routine blood analysis did not change significantly when given the PO diet. These data indicate that, even in elderly subjects, a 3g/d increase of dietary ALA could increase serum EPA and DHA in 10 mo without any major adverse effects.

著者

Churan FU Yongshou YANG Thanutchaporn KUMRUNGSEE Akiko KIMOTO Hanae IZU Norihisa KATO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.6, pp.553-560, 2020-12-31 (Released:2020-12-31)

参考文献数

44

被引用文献数

2

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The effects of low-dose alcohol on experimental animals are unclear. This study examined plasma metabolites in senescence-accelerated mice 8 (SAMP8) given low-dose ethanol, and compared them with aging progress and skeletal muscle strength. Male SAMP8 mice (10-wk-old) were given drinking water containing 0% (control), 1%, 2%, or 5% (v/v) ethanol for 14 wk. Compared with the control group, only mice who consumed 1% ethanol experienced a lower senescence score at 18 and 23 wk, as well as an increased limb grip strength at 21 wk. Plasma metabolites of control, 1% and 2% ethanol groups were analyzed by capillary electrophoresis–time-of-flight mass spectrometry (CE-TOF/MS). Among the 7 metabolites affected by ethanol, notewhorthy is the positive association of the ethanol levels in drinking water with the levels of α-ketoglutarate (antioxidant and anti-inflammatory metabolite) and hippurate (antioxidant and microbial co-metabolite) (p<0.05). Intriguingly, the levels of 2-hydroxyisobutyrate (the biomarker of energy metabolism and microbial co-metabolite) were higher in the 1% ethanol group (p<0.05), but not in the 2% ethanol group as compared to the control. Furthermore, the levels of some of the metabolites affected were correlated with some variables in the grading score of senescence and muscle strength. This study provides a novel insight into how low-dose ethanol in SAMP8 mice modulates the levels of circulating metabolites relating to chronic disease risk.

著者

Chenze SHI Lei WANG Kejun ZHOU Mingmei SHAO Yifei LU Tao WU

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.6, pp.536-544, 2020-12-31 (Released:2020-12-31)

参考文献数

30

被引用文献数

8

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To investigate changes in serum and hepatic levels of amino acids in ALD and to provide novel evidence and approaches for the prevention and treatment of ALD. Twenty specific pathogen-free SD male rats were devided into two groups, ten for the control group, and ten for the model group. Serum biochemical markers, including alanine aminotransferase, aspartate aminotransferase, laminin and hyaluronidase were measured. Histological analysis of liver tissues was performed. Serum and liver amino acids levels were quantitatively determined by ultra-high-performance liquid chromatography-tandem quadrupole mass spectrometry (UPLC-TQMS)-based targeted metabolomics. Compared with the normal group, ALD rats showed an obvious increase in the levels of β-alanine, alanine, serine, ornithine, tyrosine and the tyrosine ratio, while there was a decrease in arginine levels, the BTR ratio and Fischer’s ratio in serum. Additionally, ALD rats exhibited a significant increase in the levels of cysteine and putrescine, while there was a decrease in sarcosine, β-alanine, serine, proline, valine, threonine, ornithine, lysine, histidine, tyrosine, symmetric dimethylarginine, methionine, isoleucine and methionine-sulfoxide levels in liver tissues compared with the normal group. The serum and liver amino acids showed significant changes in ALD rats and can be considered as potential specific diagnostic biomarkers for ALD.

著者

Yuko HASEGAWA Chiharu TSUTSUMI Fusako MITSUHASHI Noriyuki KIMURA Yoshitaka IWABUCHI Shu SAKAMOTO Kazuko ISHIKAWA-TAKATA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.5, pp.441-448, 2020-10-31 (Released:2020-10-31)

参考文献数

23

被引用文献数

2

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The official testing methods for establishing nutritive values are accurate but relatively costly and time-consuming. Near infrared spectroscopy (NIRS) is potentially an alternative method that can analyze several components in a few minutes using an exclusively electronic instrument with no need for a laboratory expert. However, the accuracy of commercial NIRS spectroscopic food analyzers is not sufficient for Japanese food labeling, because of interference from moisture contained in the foods. This study aims to assess the effect of a freeze-drying pretreatment on the accuracy of NIRS food analysis. Thirty-four samples, consisting of six food items habitually consumed in Japan and cooked by different cooking methods were treated by milling then freeze-drying. They were analyzed by a commercial NIRS instrument (Calorie AnswerTM) with calibration curves developed based on other freeze-dried samples. The obtained nutritive values (energy, protein, lipid, carbohydrate and moisture) were corrected to the values before freeze-drying using the vaporized moisture content. The same samples before freeze-drying were also analyzed using the official testing methods to assess the analytical accuracy using NIRS after freeze-drying, and further analyzed using the same NIRS with the commercial calibration curves to assess the effect of freeze-drying. The accuracies were better for the freeze-dried samples than for the wet samples. The magnitude of the error in energy and carbohydrate was significantly associated with the retained moisture content in the freeze-dried sample. In conclusion, freeze-drying was an effective pretreatment for improving the accuracy of NIRS analyses of Japanese cooked foods, although it is still time-consuming and needs additional investment.

著者

Nobuhiko TACHIBANA Masanori FUKAO Tomoko IRIE Yusuke IRISAWA Hirotaka SHIRONO Motoko OARADA Takeshi NIKAWA Tetsuya FUKAYA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.5, pp.449-455, 2020-10-31 (Released:2020-10-31)

参考文献数

24

被引用文献数

2

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Although muscle atrophy can be caused by disuse and lifestyle-related syndromes, it may be possible to prevent this condition through dietary intervention. We hypothesized that a diet including red bell pepper juice (RBPJ) and soy protein isolate (SPI) would prevent muscle atrophy. Accordingly, an experimental diet containing RBPJ and/or SPI was administered for 18 d to normal C57BL/6J mice. The control group was administered a casein diet. Four days before the end of the test period, denervation-induced muscle atrophy and/or sham operation were performed. Anterior tibialis muscle samples were then obtained to assess muscle degradation and perform metabolome analysis. Under the denervation condition, the 20% SPI diet did not alter the mRNA expression levels of muscle atrophy marker genes compared with the 20% casein group. Although the diet comprising RBPJ and 20% casein did not prevent muscle atrophy compared with the control group, the diet containing RBPJ and 20% SPI did. Metabolome analysis revealed that a diet including RBPJ and SPI induced a greater than 1.5-fold change in the levels of 20 muscle atrophy-related metabolites. In particular, the level of S-adenosylmethionine, which concerned with energy metabolism and lifespan, showed a strong positive correlation with the muscle atrophy marker. These findings suggest that a diet including RBPJ and soy protein suppress gene expressions related with muscle atrophy. Further research in humans is needed to confirm whether a combination of RBPJ and SPI can indeed prevent muscle atrophy.

著者

Xinyi KANG Jiawen CUI Mingjin ZHANG Ying WANG Weichun TANG Liping CHEN

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.5, pp.402-408, 2020-10-31 (Released:2020-10-31)

参考文献数

23

被引用文献数

2

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This aim of this meta-analysis was to evaluate the association between risk of childhood type 1 diabetes and maternal 25-hydroxyvitamin D [25(OH)D] levels during pregnancy. A literature search on databases including PubMed and Embase was conducted up to December 2018. The pooled odds radio weighted mean difference (WMD) and the corresponding 95% confidence intervals (CIs) were calculated using the RevMan 5.3 software. A total of 4 studies were included in this meta-analysis. The overall analysis indicated that the maternal 25(OH)D levels during pregnancy was significantly associated with the risk of type 1 diabetes in offspring (WMD=−2.54, 95% CI=−4.65 to −0.44, p=0.02). The subgroup analyses showed that sample for detection vitamin D (serum/plasma) may not a factor influencing the results of this meta-analysis. However, gestational trimester may be a factor affecting the results. The results showed that no significant association was observed between risk of type 1 diabetes in offspring and 25(OH)D level during first or second gestational trimester (p>0.05). Lower maternal 25(OH)D levels during pregnancy is associated with higher risk of type 1 diabetes in offspring. Gestational trimester may be a factor influencing the results of this meta-analysis.

著者

玉木 七八 森岡 幸子 池田 建比古 原田 光子 浜 堯夫

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.26, no.2, pp.127-139, 1980 (Released:2009-04-28)

参考文献数

26

被引用文献数

9 12

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The biosynthesis and destruction of anserine and carnosine in the rat were investigated in vivo using radioactive β-alanine, histidine and methylhistidine. In the normal rat, the incorporation of 14C-histidine and 14C-β-alanine into carnosine was found to proceed at significant rates, but their incorporation into anserine was hardly detectable. Radioactive anserine arising from 3H-Nπ-methylhistidine was detected in gastrocnemius muscle of the rat pretreated with β-alanine. Neither anserine nor carnosine biosynthesis was found in liver, but was found in gastrocnemius muscle. At 8 hr after the administration of a single dose of 14C-histidine or 14C-β-alanine, the incorporation of radioactivity into carnosine attained a plateau, and then maintained the level for the investigated period. Incorporation of 14C-histidine into carnosine was increased about 2-fold when rats were injected in advance with f-alanine. The half-lives of histidine and β-alanine were 0.67 and 0.41 hr in liver, and 3.6 and 2.3 hr in gastrocnemius muscle, respectively. β-Alanine and histidine in rat gastrocnemius muscle disappeared at the rates of 39 and 29 nmol/wet tissue (g)/hr, respectively. The half-life of carnosine, as was determined from the decrease in carnosine contents in the gastrocnemius muscle of a rat fed a histidine-free diet, was 29 days. The rate constant of carnosine biosynthesis in rat gastrocnemius muscle was 0.321 μmol/DNA (mg)/day, that is, 0.286 μmol/wet tissue (g)/day.

著者

Adam DREWNOWSKI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.61, no.Supplement, pp.S69-S71, 2015 (Released:2015-11-24)

参考文献数

11

被引用文献数

5 10

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Food prices and diet costs contribute to socioeconomic disparities in diet quality and health. Lower-cost diets provide ample calories but lack essential nutrients. Nutrition economics can remedy health disparities by helping to identify food patterns that are nutrient-rich, affordable, and appealing. First, nutrient profiling models—such as the Nutrient Rich Food (NRF) family of indices—are able to separate foods that are energy-dense from those that are nutrient-rich. Whereas energy-dense foods contain more calories than nutrients, nutrient-rich foods contain more nutrients than calories. Second, new value metrics have identified affordable healthy foods, based on nutrients per unit cost. Third, these methods have now been applied to the analyses of individual foods and beverages, meals, menus, and the total diet. The Healthy Eating Index (HEI), based on compliance with dietary guidelines, was the principal measure of total diet quality. Although healthier diets did generally cost more, some population subgroups managed to obtain nutrient-dense diets at a lower cost. Being able to create affordable, healthy food patterns on limited budgets is an example of nutrition resilience.

著者

Lu ZHANG Shaohua HUANG Lina CAO Miaonmiao GE Yuanhong LI Jihong SHAO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.65, no.5, pp.375-382, 2019-10-31 (Released:2019-10-31)

参考文献数

47

被引用文献数

9

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Breast cancer is one of the most common cancers among women worldwide, and several studies have investigated the association of dietary patterns and breast cancer. However, findings of studies are inconclusive. Therefore, we aimed to conduct a meta-analysis to summarize the available data regarding the association of vegetable-fruit-soybean dietary pattern and breast cancer. A systematic literature search was conducted via PubMed, Web of Science and EMBASE to identify eligible cohort studies before February 2019. A total of 12 cohort studies were included in the meta-analysis. The summary relative risks (RR) with 95% CI were calculated with a fixed-effects model. The overall RR of breast cancer for the highest versus lowest intake of vegetable-fruit-soybean dietary pattern was 0.87 (95% CI, 0.82-0.91), with little heterogeneity (p=0.73, I2=0%). There was no obvious publication bias according to funnel plot and Begg’s and Egger’s test. In summary, the evidence from this meta-analysis indicates that vegetable-fruit-soybean dietary pattern was inversely associated with breast cancer. However, well-designed randomized controlled trials are needed to elicit the clear effect of vegetable-fruit-soybean dietary pattern and breast cancer. Women can reduce the risks of breast cancer by eating more fruits and vegetables and soybeans, which is a constructive suggestion.

著者

Bilgehan PEKINER Serpil NEBIOGLU

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.40, no.5, pp.401-410, 1994 (Released:2009-04-28)

参考文献数

35

被引用文献数

4 6

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Healthy individual were given 2g of vitamin C per day for 2 months. Whole blood iron, ascorbic acid, hemoglobin, and serum ceruloplasmin were determined at the beginning, and 1 or 2 months after the start of the experiment. The concentration of ascorbic acid was observed to increase significantly in the blood, while blood iron, hemoglo-bin, and serum ceruloplasmin levels significantly increased at the end of the 1st month, but decreased to control levels at the end of the 2nd month. Male albino guinea pigs were administered 8, 180, and 360mg of vitamin C per day for 2 months. Liver ferritin iron, liver copper, serum copper, and serum ceruloplasmin levels significantly decreased, but there was no significant change in hemosiderin iron while blood ascorbic acid signifi-cantly increased at the end of the 2 month period. There was no significant change in serum iron and hematocrit levels. These results suggest that vitamin C has an antagonistic effect on copper metabolism in guinea pigs but not in humans either on copper or iron metabolisms.

著者

Masashige SUZUKI Tatsuya DOI Sang Jik LEE Koji OKAMURA Seiichi SHIMIZU Goro OKANO Yuji SATO Yoshiharu SHIMOMURA Tohru FUSHIKI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.45, no.4, pp.401-409, 1999 (Released:2009-04-28)

参考文献数

20

被引用文献数

13 17

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To study the effect of meal timing after exercise on body composition, 20 male rats were assigned to either a group fed a meal right after exercise (R) or a group fed a meal 4 h after exercise (L). Resistance exercise (squatting) was conducted from 6:00 to 7:00, 3 d/wk for 10 wk. Meals were consumed from 7:00 to 8:00 and from 19:00 to 20:00 for R, and from 11:00 to 12:00 and from 19:00 to 20:00 for L. The room was lighted from 7:00 to 19:00. After 10 wk, the body weight was comparable between the groups. The hindlimb muscle weight was higher in R than in L by 6% (p<0.05), whereas the sum of the weight of perirenal, epididymal, and mesenteric adipose tissues was lower in R than in L by 24% (p<0.01). The soleus lipoprotein lipase (LPL) activity was higher in R than in L by 70% (p<0.01), and the activity negatively correlated with the adipose tissue weight (r=-0.49, p<0.05). These results suggest the possibility that ingesting a meal right after resistance exercise may contribute to an increase in the muscle mass and to a decrease in the adipose tissue compared to ingesting a meal several hours later.

著者

Kenichiro SHIMIZU Sumie TAKEDA Hiroyasu NOJI Nobuyoshi HIROSE Yoshinori EBIHARA Yasumichi ARAI Michiyo HAMAMATSU Susumu NAKAZAWA Yasuyuki GONDO Kanoko KONISHI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.49, no.2, pp.133-138, 2003 (Released:2009-06-15)

参考文献数

16

被引用文献数

14 19

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We have previously reported that centenarians (persons≥100 y old) in Tokyo prefer dairy products. Dietary preferences may be associated with longevity. The aim of the present study was to investigate the relationship between dietary patterns and further survival in centenarians. During 1992-1999, we examined the dietary practices of 104 centenarians (29 men and 75 women; mean age, 100.3±0.9 y) who lived in the Tokyo metropolitan area. Dietary patterns were classified by k-means cluster analysis. As clinical co-variables, we considered activities of daily living, cognitive function, nutritional status, presence of important disease, gender, and age at the time of the initial survey. Survival data were recorded yearly until 2001, and then tested with Kaplan-Meier analysis and the log rank statistic. Four dietary patterns were identified a pattern preferring vegetables (n=33), a pattern preferring dairy products (n=26), a pattern preferring beverages (n=10), and a pattern preferring cereals (n=35). No clinical variables differed between the four dietary patterns. In 2001, 28 centenarians were still alive. The survival rate for those preferring dairy products was the highest of the four dietary patterns; in particular, being significantly higher than the pattern preferring beverages (p=0.048). A dietary pattern preferring dairy products was associated with increased survival in Tokyo-area centenarians.

著者

Iwao KOIZUMI Yoshihiko SUZUKI J. J. KANEKO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.37, no.6, pp.545-554, 1991 (Released:2009-04-28)

参考文献数

11

被引用文献数

11 13

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The fatty acid composition of the intramuscular lipids of cattle, pigs and birds were determined relative to breed and feeding regime. The cattle included Yellow Cattle, Hereford and Japanese Black; pigs included Wild-boar, Touyuens and Yorkshires; the birds were Wild-birds, Jungle-fowl and broilers. The pen fed animals such as Japanese Black cattle and Yorkshire pigs had a higher amounts of oleic acid, palmitic acid and palmitoleic acid. On the other hand, wild or pasture fed animals such as the Herefords, Wild-boars and Touyuens had higher amounts of ω-3 fatty acids such as α-linolenic acid, icosapentaenoic acid and ω-6 fatty acids such as linoleic acid and arachidonic acid. Among Wild-fowl, open-yard fed birds or broilers, there was no difference in fatty acid composition. It is suggested the meat of pasture fed or wild fed animals such as Herefords, Yellow Cattle and Wild-boar is better for health than meat from pen fed animals.

著者

Beong Ou LIM Nak Sul SEONG Ryo Won CHOUE Jong Dal KIM Hyeon Yong LEE Sun Yeou KIM Byung Pal YU Tae Il JEON Doug Ki PARK

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.49, no.4, pp.292-296, 2003 (Released:2009-04-28)

参考文献数

38

被引用文献数

13 22

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In the current study, we show the anti-oxidative and hypocholesterol effects of aloe vera in the liver. Male specific pathogen-free (SPF) Fischer 344 rats were randomly assigned to one of four groups: Group A (control) was fed test chow without aloe supplementation; Group B was fed a diet containing a 1% (per weight basis) freeze-dried aloe filet; Group C was fed a diet containing a 1% (per weight basis) charcoal-processed, freeze-dried aloe filet; and Group D was fed a diet containing a-charcoal-processed freeze-dried, whole leaf aloe (0.02% per weight basis) in the drinking water. Our results show that a life-long intake of aloe had superior anti-oxidative action against lipid peroxidation in vivo, as indicated by reduced levels of hepatic phosphatidylcholine hydroperoxide. Additional anti-oxidative action was evidenced by enhanced superoxide dismutase (SOD) and catalase activity in groups B and C. Furthermore, our study revealed that hepatic cholesterol significantly increased in the control group during aging in contrast to the aloe-supplemented groups, which showed approximately 30% lower cholesterol levels, thereby an effective hypocholesteremic efficacy. In this report, we suggest that life-long dietary aloe supplementation suppresses free radical-induced oxidative damage and age-related increases in hepatic cholesterol.

著者

Miho NOZUE Kyungyul JUN Yoko ISHIHARA Yasuko TAKETA Akiko NARUSE Narumi NAGAI Katsushi YOSHITA Hiromi ISHIDA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.59, no.1, pp.22-28, 2013 (Released:2013-03-28)

参考文献数

22

被引用文献数

1 1

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The purpose of this study was to estimate the usual intake distribution of calcium and vitamin B1 of fifth-grade children based on a 3-d dietary survey and to assess nutrient intake using Dietary Reference Intakes (DRIs 2010). A cross-sectional study was undertaken from October 2007 to February 2008 in schools located in Tokyo and Okayama, Japan. A total of 94 fifth-grade children attending 5 elementary schools participated in the study. The weighed plate waste method and observation were used to collect data on the school lunches and dietary records by children, accompanied by photographs used to collect data on meals at home. The study lasted 3 d, 2 non-consecutive days with school lunches and 1 d without. The estimated proportion of subjects below the Estimated Average Requirement (EAR) for calcium intake with milk in the school lunch decreased by 40% compared to the calcium intake without milk in the school lunch. Vitamin B1 intake from less than 0.45 mg/1,000 kcal fortified rice was estimated to be 0%. The intake distribution of calcium has increased by 150 mg by taking milk and the intake distribution of vitamin B1 has increased 0.20 mg by taking fortified rice in the school lunch. Calcium and vitamin B1 intake in the school lunch has changed the distribution of calcium and vitamin B1 intake upward, and decreased the number of estimated subjects that were below EAR. However, the distribution was not shifted across the board and the shape of the distribution has changed.

著者

Sachie UEDA Masanori TANAHASHI Yuko HIGAKI Kayoko IWATA Yoshinori SUGIYAMA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.63, no.5, pp.291-297, 2017 (Released:2017-12-08)

参考文献数

24

被引用文献数

7

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Coffee polyphenols (CPPs) derived from coffee beans have beneficial effects on blood pressure and vascular endothelial function. In addition, CPPs suppress ultraviolet light induced erythema. However, the effects of CPPs on dry skin and cutaneous vascular function have not been clarified. We investigated the effects of CPPs on dry skin and the recovery rate (RR) of skin temperature after a cold-stress test as a measure of vascular function in subjects with visible scaliness in a double-blind, placebo-controlled, randomized study. The subjects were divided into two groups, the CPP group and the Placebo group. In the CPP group, the subjects ingested a beverage containing 297.8 mg CPPs every day for 4 wk. The degree of skin dryness was assessed quantitatively using a Visioscan to evaluate skin scaliness and smoothness. A subjective evaluation using a visual analog scale (VAS) of skin smoothness was also used. As a result, the scaliness and smoothness of cheek skin was significantly improved after 4 wk in the CPP group compared to the Placebo group. The improvements of the VAS score on ‘skin smoothness’ and the RR were also observed in the CPP group but the difference was not statistically significant. However, when the CPP group was divided into subgroups of high RR and low RR, the improvement of the RR was significant in the low RR subgroup. In conclusion, our results suggest that CPPs improve skin scaliness and play a role in cutaneous blood flow regulation after cold stress.

著者

Saki KANEKO Takumi YAMAZAKI Kakeru KOHNO Ayami SATO Kazunori KATO Tomohiro YANO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.65, no.3, pp.272-277, 2019-06-30 (Released:2019-06-30)

参考文献数

26

被引用文献数

4

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The reoccurrence of androgen-dependent prostate cancer after anti-androgen therapy mainly depends on prostate cancer stem-like cells. To reduce the risk, it is important to delete the cancer stem-like cells. Furthermore, to induce differentiation of cancer stem-like cells is critical to abrogate stemness of the cells. Therefore, we tried to investigate a possibility on the establishment of a new effective therapy to eradicate the cancer stem-like cells via the induction of differentiation in this study. Prostate cancer stem-like cells from an androgen-dependent prostate cancer cell line (LNCaP cell) had severe resistance against an anti-androgen therapeutic agent. We selected Bowman-Birk inhibitor (BBI) from soybeans reported as a chemopreventive agent in prostate cancer to differentiate the caner stem-like cells and α-tocopheryl succinate (TOS) known as a mitocan to induce effectively cytotoxic effect against the cancer stem-like cells. In fact, only TOS treatment had cytotoxic effect against the cancer stem-like cells, but the addition of BBI treatment to the cells treated with TOS reinforced TOS-mediated cytotoxicity in the cancer stem-like cells. This reinforcement coincided with the combination-enhanced apoptosis in the stem-like cells. Also, we confirmed caspase9-caspase3 cascade mainly contributed to the enhancement of the cytotoxicity in the stem-like cells caused by the combination, indicating that the reinforcement of BBI on TOS-mediated apoptosis via mitochondria related to the enhancing cytotoxic effect of the combination on the prostate cancer stem-like cells. Overall, it seems that the combination is an effective new approach to reduce the reoccurrence of prostate cancer targeting prostate cancer stem cells.