- 著者
- Yoshimune Nonomura Haruna Ogura Haruhi Niino Tatsunari Ueda Masashi Shibata
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.4, pp.421-428, 2023 (Released:2023-03-30)
- 参考文献数
- 19
Organogels are attractive formulations in cosmetics, food, and pharmaceuticals. They exhibit characteristic frictional and mechanical responses during the collapse of a mesostructure. In this study, the friction dynamics of organogels composed of five different waxes (paraffin wax, microcrystalline wax, ceresin, candelilla wax, and carnauba wax) and liquid paraffin were evaluated using a sinusoidal motion friction evaluation system. All organogels exhibited a velocity dependence of friction coefficient that increased with the acceleration of the contact probe. Depending on the ease of the crystal formation of the waxes in liquid paraffin, hydrocarbon-based waxes formed soft organogels with a low-friction coefficient, whereas ester-based, highly polar waxes formed organogels that were hard and had a high-friction coefficient.
- 著者
- Satoshi Wanezaki Takumi Taniwaki Junki Miyamoto Masashi Hosokawa
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.3, pp.303-312, 2023 (Released:2023-03-03)
- 参考文献数
- 39
- 被引用文献数
- 1
Dietary fish oil containing n-3 polyunsaturated fatty acids provides health benefits by lowering lipid levels in the liver and serum. β-Conglycinin (βCG) is a major constituent protein in soybean with many physiological effects, such as lowering blood triglyceride levels, preventing obesity and diabetes, and improving hepatic lipid metabolism. However, the combined effects of fish oil and βCG remain unclear. Here, we investigated the effects of a dietary combination of fish oil and βCG on lipid and glucose parameters in diabetic/obese KK-A y mice. KK-A y mice were divided into three groups: control, fish oil, and fish oil + βCG; these groups were fed a casein-based diet containing 7% (w/w) soybean oil, a casein-based diet containing 2% (w/w) soybean oil and 5% (w/w) fish oil, and a βCG-based diet containing 2% (w/w) soybean oil and 5% (w/w) fish oil, respectively. The effects of the dietary combination of fish oil and βCG on blood biochemical parameters, adipose tissue weight, expression levels of fat- and glucose metabolism-related genes, and cecal microbiome composition were evaluated. The total white adipose tissue weight (p < 0.05), levels of total serum cholesterol (p < 0.01), triglyceride (p < 0.01), and blood glucose (p < 0.05), and expression levels of fatty acid synthesis-related genes (including Fasn (p < 0.05) and Acc (p < 0.05)), and glucose metabolism-related genes (such as Pepck (p < 0.05)) were lower in the fish oil and fish oil + βCG groups than in the control group. Furthermore, the relative abundance of Bacteroidaceae and Coriobacteriaceae differed significantly between the fish oil + βCG and control groups. These findings suggest that dietary intake of fish oil + βCG may prevent obesity and diabetes, alleviate lipid abnormalities, and alter the gut microbiome composition in diabetic/obese KK-A y mice. Further research is needed to build on this study to evaluate the health benefits of major components of Japanese food.
- 著者
- Katsuya Nouzaki Ryoichi Tanaka Yuya Sato Tomohiro Inaba Tomo Aoyagi Tomoyuki Hori Hiroshi Yanagishita Hiroshi Habe
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.3, pp.357-367, 2023 (Released:2023-03-03)
- 参考文献数
- 27
The discharge of high-strength oily wastewater adversely affects the environment; therefore, the treatment of wastewater containing fats, oils, and grease from the food industry is of importance. In this study, we used a membrane bioreactor (MBR) to treat Ramen noodle-soup wastewater, and we evaluated the optimal oil concentration in the wastewater for the startup of the MBR treatment in winter and summer. The MBR system had a sufficient startup in both seasons when fed with a 20-fold dilution of the original oily wastewater, containing approximately 950 to 1,200 mg/L oil and approximately 3,000 to 4,400 mg/L biological oxygen demand (BOD; BOD-SS load of 0.1 to 0.2 kg/kg/d). The reactor performance in winter were relatively stable during the operation. While, activated sludge microbes in summer were not highly active with a 40-fold dilution of wastewater, because of the decreased mixed liquor suspended solid concentration during the operation period. Population shifts in the sludge microbiome with increasing oil concentrations were analyzed using high-throughput sequencing, and the relative abundance of operational taxonomic units belonging to the phylum Bacteroidetes were highest in both winter and summer when fed with 20-fold dilution of the wastewater. In particular, the family Chitinophagaceae was dominant, with relative abundances of 13.5% in winter and 5.1% in summer, suggesting that this family may play important roles in the startup of a MBR treating the wastewater.
- 著者
- Xiwen Yang Ping Jiang Yahui Luo Yixin Shi
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.1, pp.69-77, 2023 (Released:2023-01-07)
- 参考文献数
- 22
- 被引用文献数
- 1
As a unique traditional vegetable oil in China, camellia seed oil has very high edible value. Camellia seed kernel is mainly composed of fatty acids, which not only determines the oil yield of camellia seed, but also exert an important impact on the storage performance of camellia seed. In order to quickly and accurately determine the fatty acid content of camellia seed, this paper took camellia seed as the research object, used hyperspectral technology to determine the fatty acid content of camellia seed, and establishes a spectral model. 8 pretreatment methods, such as Savitzky-Golay smoothing, normalization, baseline correction, multivariate scattering correction, standard normal variable transformation, detrending algorithm, first derivative and second derivative, were adopted in this paper. The spectral prediction model of fatty acid content in camellia seed was established by combining 4 modeling methods: principal components regression (PCR), partial least square regression (PLSR), back propagation neural network (BP), radial basis function neural network (RBF). The optimal prediction model was selected by comparing the coefficient of determination (R2) and root mean square error (RMSE) of various models. The results showed that the spectral sensitive bands with high correlation coefficients (r) were 410-420 nm, 450-460 nm, 490-510 nm, 545-580 nm, 845-870 nm and 905-925 nm, respectively. The r obtained by MSC pretreatment of spectral data was the largest. The data obtained by 8 different pretreatment methods combined with RBF neural network model was the best, in which the average value of coefficient of determination (RC2) in the calibration set was 0.8654, and the root mean square error of calibration (RMSEC) was 0.0777; the average value of coefficient of determination (RP2) and root mean square error of prediction (RMSEP) in the prediction set model were 0.8437 and 0.0827, respectively. It could be seen that the best accuracy could be achieved by MSC pretreatment combined with RBF neural network modeling. This paper can provide reference for rapid nondestructive detection of fatty acid content in camellia seed by hyperspectral technology.
- 著者
- Xiwen Yang Ping Jiang Yahui Luo Yixin Shi
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess22139, (Released:2022-12-12)
- 被引用文献数
- 1
As a unique traditional vegetable oil in China, camellia seed oil has very high edible value. Camellia seed kernel is mainly composed of fatty acids, which not only determines the oil yield of camellia seed, but also exert an important impact on the storage performance of camellia seed. In order to quickly and accurately determine the fatty acid content of camellia seed, this paper took camellia seed as the research object, used hyperspectral technology to determine the fatty acid content of camellia seed, and establishes a spectral model. 8 pretreatment methods, such as Savitzky-Golay smoothing, normalization, baseline correction, multivariate scattering correction, standard normal variable transformation, detrending algorithm, first derivative and second derivative, were adopted in this paper. The spectral prediction model of fatty acid content in camellia seed was established by combining 4 modeling methods: principal components regression (PCR), partial least square regression (PLSR), back propagation neural network (BP), radial basis function neural network (RBF). The optimal prediction model was selected by comparing the coefficient of determination (R2) and root mean square error (RMSE) of various models. The results showed that the spectral sensitive bands with high correlation coefficients (r) were 410-420 nm, 450-460 nm, 490-510 nm, 545-580 nm, 845-870 nm and 905-925 nm, respectively. The r obtained by MSC pretreatment of spectral data was the largest. The data obtained by 8 different pretreatment methods combined with RBF neural network model was the best, in which the average value of coefficient of determination (RC2) in the calibration set was 0.8654, and the root mean square error of calibration (RMSEC) was 0.0777; the average value of coefficient of determination (R2P) and root mean square error of prediction (RMSEP) in the prediction set model were 0.8437 and 0.0827, respectively. It could be seen that the best accuracy could be achieved by MSC pretreatment combined with RBF neural network modeling. This paper can provide reference for rapid nondestructive detection of fatty acid content in camellia seed by hyperspectral technology.
- 著者
- Winranath Kanprakobkit Somlak Wannarumon Kielarova Uthai Wichai Nuntawan Bunyapraphatsara Filip Kielar
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.1, pp.87-97, 2023 (Released:2023-01-07)
- 参考文献数
- 43
- 被引用文献数
- 2
The fatty acid composition of coconut oil was modified using enzyme catalyzed interesterification with the aim of obtaining a product more alike to commercial MCT oils. This modification was carried out with the aim to obtain a product with some of the health benefits shown by MCT oils. Initially, lipase B from Candida antarctica immobilized on acrylic resin and lipozyme TL IM were tested as enzyme catalysts for the reaction. The enzyme catalysts have shown similar performance and lipozyme TL IM has been chosen as the catalyst based on its lower cost. The effects of reaction time, oil to methyl octanoate ratio, and enzyme loading on the reaction performance have been investigated with response surface methodology (RSM) utilizing the Box-Behnken approach. The optimized reaction was scaled up to 20 g. The possibility to source the medium chain fatty acid esters from coconut oil fatty acid distillate using a simple procedure was demonstrated and the possibility to use these esters for the interesterification of coconut oil has been demonstrated as well.
- 著者
- Lok Kumar Shrestha Rekha Goswami Shrestha Sabina Shahi Chhabi Lal Gnawali Mandira Pradhananga Adhikari Biswa Nath Bhadra Katsuhiko Ariga
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.72, no.1, pp.11-32, 2023 (Released:2023-01-07)
- 参考文献数
- 201
- 被引用文献数
- 6
Nanoarchitectonics integrates nanotechnology with numerous scientific disciplines to create innovative and novel functional materials from nano-units (atoms, molecules, and nanomaterials). The objective of nanoarchitectonics concept is to develop functional materials and systems with rationally architected functional units. This paper explores the progress and potential of this field using biomass nanoarchitectonics for supercapacitor applications as examples of energetic materials and devices. Strategic design of nanoporous carbons that exhibit ultra-high surface area and hierarchically pore architectures comprising micro- and mesopore structure and controlled pore size distributions are of great significance in energy-related applications, including in high-performance supercapacitors, lithium-ion batteries, and fuel cells. Agricultural wastes or natural biomass are lignocellulosic materials and are excellent carbon sources for the preparation of hierarchically porous carbons with an ultra-high surface area that are attractive materials in high-performance supercapacitor applications due to high electrical and ion conduction, extreme porosity, and exceptional chemical and thermal stability. In this review, we will focus on the latest advancements in the fabrication of hierarchical porous carbon materials from different biomass by chemical activation method. Particularly, the importance of biomass-derived ultra-high surface area porous carbons, hierarchical architectures with interconnected pores in high-energy storage, and high-performance supercapacitors applications will be discussed. Finally, the current challenges and outlook for the further improvement of carbon materials derived from biomass or agricultural wastes in the advancements of supercapacitor devices will be discussed.
- 著者
- Ardiansyah
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.70, no.11, pp.1565-1574, 2021 (Released:2021-11-03)
- 参考文献数
- 63
- 被引用文献数
- 3
Rice bran is a by-product of the rice milling process, which refers to the processing of brown rice into polished rice. It contains a considerable amount of functional bioactive compounds. However, the utilization of these compounds is limited and calls for an effort to ferment rice bran. One of the methods that can significantly increase the added value of rice bran as well as its bioactivity is the solid-state fermentation. It can also be one of the strategies that help in the production of rice bran as a functional ingredient with higher bioactivity for health promotion.
- 著者
- Noriaki Nagai Tetsushi Yamamoto Wataru Tanabe Yoshimasa Ito Satoshi Kurabuchi Kuniko Mitamura Atsushi Taga
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.64, no.3, pp.331-335, 2015 (Released:2015-03-01)
- 参考文献数
- 16
- 被引用文献数
- 8 12
We investigate whether maple syrup is a suitable sweetener in the management of type 2 diabetes using the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The enhancement in plasma glucose (PG) and glucose absorption in the small intestine were lower after the oral administration of maple syrup than after sucrose administration in OLETF rats, and no significant differences were observed in insulin levels. These data suggested that maple syrup might inhibit the absorption of glucose from the small intestine and preventing the enhancement of PG in OLETF rats. Therefore, maple syrup might help in the prevention of type 2 diabetes.
- 著者
- Azusa Nishino Kazuhisa Sugimoto Haruyo Sambe Takashi Ichihara Takeshi Takaha Takashi Kuriki
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.67, no.7, pp.863-869, 2018 (Released:2018-07-01)
- 参考文献数
- 29
- 被引用文献数
- 8 16
Generation of singlet oxygen by solar ultraviolet (UV) radiation causes acute inflammatory responses in the skin. Accumulation of singlet-oxygen-quenching antioxidants in the skin can suppress this photo-oxidative stress. This study evaluated the effect of dietary xanthophylls from red paprika fruit extract on UV-induced skin damage. A randomised double-blind placebo-controlled parallel group comparison study involving 46 healthy volunteers was performed. The minimal erythema dose (MED) of each individual was determined prior to the study. A capsule containing paprika xanthophylls (9 mg) or a placebo was administered daily for 5 weeks. The MED, minimal tanning dose (MTD), skin physiology parameters (skin color, hydration, and barrier function), and facial skin physiology parameters were evaluated at weeks 0, 2, and 4. The MED of the verum group at 2 and 4 weeks after administration was significantly higher than that of the placebo group. At 4 weeks, the suppression of UV-induced skin darkening by the verum diet was significantly greater than that of the placebo. There were no significant differences in facial skin parameters between the verum and placebo groups. Our results indicate the efficacy of dietary paprika xanthophylls in suppression of UV-induced skin damage.
- 著者
- Chikara Kato Isabella Supardi Parida Satoshi Maeda Tsuyoshi Mikekado Shunji Kato Susumu Takekoshi Kiyotaka Nakagawa
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess22284, (Released:2022-11-07)
Following a growing interest in the physiological effects of pyrroloquinoline quinone (PQQ), more cell culture experiments have begun to elucidate its mechanism of action. However, to our knowledge, no reports have used instrumental analysis, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS), to study cellular uptake of PQQ. In addition, despite the propensity of PQQ to react with amino acids and other compounds, only a handful of cell culture experiments have been conducted on PQQ derivatives. In the present study, we prepared PQQ derivatives by reacting PQQ with various amino acids and used them as reference standards for optimizing the LC-MS/MS analysis conditions to detect PQQ and its derivatives. Using this method, we evaluated the uptake of PQQ into mouse 3T3-L1 cells and found that most PQQ added to the medium was taken up by the cells in its unchanged form, while some PQQ reacted with amino acids in the medium and was taken up by the cells as PQQ derivatives. These results suggest that PQQ derivatives may contribute to the physiological effects of PQQ. To further elucidate the function of PQQ, it is necessary for future studies to clarify the activity of PQQ derivatives and to evaluate the types of PQQ present in food, animal, and cell samples in more detail.
- 著者
- Mami Hayasaki Minami Iwakiri Akane Shikata Machi Oyama Noe Souda Yoshihiko Akakabe
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.71, no.11, pp.1663-1668, 2022 (Released:2022-10-28)
- 参考文献数
- 30
- 被引用文献数
- 2
The aim of this study was to identify and characterize the aroma components of absolute oil from natsudaidai (Citrus natsudaidai Hayata) flowers. A total of 43 aroma components were detected in the absolute oil of natsudaidai flowers using a headspace solid phase microextraction (SPME)-gas chromatography-mass spectrometry (GC-MS). The most abundant components from the absolute oil was linalool (31.14%), followed by methyl anthranilate, γ-terpinene, p-cymene, (E)-β-ocimene, limonene, indole and α-terpineol. The configuration of linalool from the absolute oil was assigned as (S)-form and its optical purities were determined as 89.36±0.36% enantiomeric excess using a SPME-chiral GC. These results indicated that the composition of aroma components in the absolute oil would influence the overall aroma qualities of natsudaidai flowers and the physiological effects on human.
- 著者
- Koji Nagao Kazusa Nakamitsu Hiroki Ishida Kazuaki Yoshinaga Toshiharu Nagai Hoyo Mizobe Koichi Kojima Teruyoshi Yanagita Fumiaki Beppu Naohiro Gotoh
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.63, no.10, pp.979-985, 2014 (Released:2014-10-01)
- 参考文献数
- 29
- 被引用文献数
- 22 23
The effects on lipid metabolism of four different n-3 highly unsaturated fatty acids (n-3HUFA) including eicosapentaenoic acid (EPA, 20:5n-3), docosapentaenoic acid (DPA, 22:5n-3), docosahexaenoic acid (DHA, 22:6n-3), and tetracosahexaenoic acid (THA, 24:6n-3) were compared in the HepG2 cell model. None of the n-3HUFAs affected the viability of the cells. THA exerted the strongest suppression on the synthesis of triacylglycerol and cholesteryl ester (ChE), and the order of the strength of suppression was found to be THA > DHA > DPA > EPA. The mRNA level of fatty acid synthase was suppressed by the n-3HUFAs and the order of the strength of suppression by n-3HUFAs was the same in both triacylglycerol and ChE synthesis. These findings support previous animal test results using EPA, DPA, and DHA. In conclusion, both the number of carbon atoms and double bonds in an n-3HUFA structure has an effect on lipid metabolism in HepG2 cells.
- 著者
- Xiaojun Pang Haojun Huang Yuyu Wei Jiyong Leng
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.71, no.9, pp.1375-1385, 2022 (Released:2022-09-01)
- 参考文献数
- 44
- 被引用文献数
- 1
Glioblastoma multiforme or GBM is a destructive malignancy of the central nervous system and is accountable for leading cause of cancer related mortality. Inadequate success rate of surgical interventions and development of resistance towards the current therapeutical regime provides impetus for exploring novel therapeutical interventions against the disease. Recently, several epidemiological studies have explored the plausible utility of natural, dietary compounds in influencing the development, progression, and cancer metastasis. Recently, different phytoconstituents of Cassia angustifolia were found to be associated with anti-microbial, anti-cancer and anti-inflammatory effects. Therefore, the aim of the present study was to evaluate the anti-proliferative efficacy of ethanolic leaf extract of C. angustifolia (LCaEt-OH) against rat derived glioblastoma C6 cells. Briefly, the anti-proliferative potential of LCaEt-OH was assessed using MTT assay, quantitative estimation of ROS, and evaluation of mitochondrial membrane potential (ΔΨm). Moreover, the activity of caspases involved in intrinsic apoptotic pathways was also investigated using colorimetric kit followed by quantitative RT-PCR evaluation of modulation in gene expressions triggered due to LCaEt-OH treatment. Treatment of LCaEt-OH on C6 cells elucidated substantial dose-dependent decline in cellular viability. Furthermore, LCaEt-OH showed its efficacy in substantially enhancing intracellular ROS. LCaEt-OH also incited apoptosis in C6 cells by instigating nuclear condensation and dissipation of ΔΨm. In addition, LCaEt-OH mediated instigation of apoptosis was directly influenced by increased activity of caspases indispensable for intrinsic apoptotic pathway. These conclusive evidences indicate towards anticancer efficacy of LCaEt-OH against C6 cells.
- 著者
- Yoshimune Nonomura Urara Tsuchiya Mayu Taguchi Reiichiro Tsuchiya Takehiro Goto
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess22083, (Released:2022-07-06)
- 被引用文献数
- 2
Frictional properties are one of the most important physical factors in the design of cosmetic dispersions in which solid particles are dispersed in a liquid. The effects of ingredients and formulations on frictional properties have been previously reported. In this study, the frictional properties of 33 cosmetic dispersions were evaluated using a sinusoidal motion friction evaluation system when applied on an artificial skin. A detailed analysis of the velocity dependence of the friction coefficient demonstrated that all cosmetic dispersions exhibited stabile pattern and the friction behavior did not change during the round trip. We analyzed friction-based parameters by principal component analysis and demonstrated that the principal components Z1 and Z2 include the static friction coefficient μs, kinetic friction coefficient μk, delay time δ, and viscosity coefficient C, and that these factors are involved in characterizing friction dynamics. The cluster analysis on Z1 and Z2 suggested that these dispersions can be classified in three groups with respect to friction dynamics. These results can help understand the characteristics of cosmetics and control their function and utility.
- 著者
- Hiroko Takumi Kazuko Kato Hiroki Nakanishi Maiko Tamura Takayo Ohto-N Saeko Nagao Junko Hirose
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.71, no.7, pp.947-957, 2022 (Released:2022-07-01)
- 参考文献数
- 36
- 被引用文献数
- 10
Precision nutrition, also referred to as personalized nutrition, focuses on the individual to determine the individual’s most effective eating plan to prevent or treat disease. A precision nutrition for infants requires the determination of the profile of human milk. We compared the lipid profiles of the foremilk (i.e., the initial milk of a breastfeed) and hindmilk (the last milk) of six Japanese subjects and evaluated whether a human milk lipid profile is useful for precision nutrition even though the fat concentration fluctuates during lactation. We detected and quantified 527 species with a lipidome analysis by liquid chromatography-tandem mass spectrometry. The fat concentration in hindmilk (120.6 ± 66.7 μmol/mL) was significantly higher than that in foremilk (68.6 ± 33.3 μmol/mL). While the total carbon number of fatty acids in triglyceride (TG) was highest in C52 for all subjects, the second or third number differed among the subjects. Both the distribution of total carbon number of fatty acids included in TG and the distribution of fatty acids in TG classified by the number of double bonds were almost the same in the foremilk and hindmilk in each subject. The lipids levels containing docosahexaenoic acid and arachidonic acid in total lipids of the foremilk and the hindmilk were almost the same in each subject. Among the sphingolipids and glycerophospholipids, the level of sphingomyelin was the highest in four subjects’ milk, and phosphatidylcholine was the highest in the other two subjects’ milk. The order of their major species was the same in each foremilk and hindmilk. A clustering heatmap revealed the differences between foremilk and hindmilk in the same subject were smaller than the differences among individuals. Our analyses indicate that a human-milk lipid profile reflects individual characteristics and is a worthwhile focus for precision nutrition.
- 著者
- Issei Takeuchi Yuuto Kato Kimiko Makino
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.70, no.3, pp.341-348, 2021 (Released:2021-03-04)
- 参考文献数
- 35
- 被引用文献数
- 1 3
The effects of polyvinyl alcohol (PVA) on the release behavior of polymer nanoparticles from nanocomposite particles using amino acids were investigated. Rifaximin (RFX) was used as a hydrophobic drug model. RFX-loaded poly(L-lactide-co-glycolide) (PLLGA) nanoparticles were prepared using an antisolvent diffusion method. They were then spray-dried with equal amounts of amino acids to prepare the nanocomposite particles. The mean diameters of nanocomposite particles were 2.86-5.42 μm. The particle size increased as the concentration of PVA aqueous solution increased. The mean diameters of RFX-loaded PLLGA nanoparticles were 150-160 nm; however, the particle size distributions of those prepared using 0.25% (w/v) PVA aqueous solution differed significantly immediately after preparation and after redispersion from nanocomposite particles. The release test results of nanocomposite particles revealed that those prepared using 0.25% and 0.50% (w/v) aqueous PVA solutions rapidly released RFX. In contrast, particles prepared using 2.00 and 4.00% (w/v) PVA aqueous solution showed sustained drug release. The results of drug release tests of nanoparticles redispersed from nanocomposite particles showed that the nanoparticles prepared using 0.50% and 2.00% (w/v) PVA aqueous solution suppressed the initial burst. Therefore, we considered that the results of the drug release behavior of the nanoparticles in these particles reflectsreflect the release behavior of the nanoparticles from the nanocomposite particles. These results indicate that the rate of redispersion from nanocomposite particles to nanoparticles can be controlled by changing the concentration of PVA aqueous solution.
- 著者
- Sahar Y. Al-Okbi Doha A. Mohamed Thanaa E. Hamed Amr E. Edris Karem Fouda
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.67, no.3, pp.345-353, 2018 (Released:2018-03-01)
- 参考文献数
- 58
- 被引用文献数
- 7 8
The aim of the present research was to investigate the effect of fish oil, crude Nigella sative oil and combined fish oil/Nigella sative volatile oil as hepato-regenerative and renal protective supplements. The oils were administered as emulsions to rat model with liver injury induced by CCl4. Plasma activities of transaminases (AST and ALT) were evaluated as liver function indicators, while plasma creatinine and urea and creatinine clearance were determined as markers of kidney function. Plasma malondialdehyde (MDA), nitrite (NO) and tumor necrosis factor-α (TNF-α) were estimated to assess the exposure to oxidative stress and subsequent inflammation. Liver fat was extracted and their fatty acids´ methyl esters were determined using gas chromatography. Results showed that plasma activities of AST and ALT were significantly higher in CCl4 control group compared to control healthy group. Plasma levels of creatinine and urea increased significantly in CCl4 control, while creatinine clearance was reduced significantly in the same group. All rat treated groups given the three oil emulsions showed improvement in liver function pointing to the initiation of liver regeneration. The combination of fish oil/Nigella sative volatiles showed the most promising regenerative activity. Oxidative stress and inflammation which were increased significantly in CCl4 control group showed improvement on administration of the three different oil emulsions. Fatty acids methyl ester of liver fat revealed that rats treated with fish oil/Nigella sative volatile oil presented the highest content of unsaturated fatty acids (45.52% ± 0.81) while fish oil showed the highest saturated fatty acids (53.28% ± 1.68). Conclusion; Oral administration of oil emulsions of native fish oil, Nigella sative crude oil and combined fish oil/Nigella sative volatile oil reduced liver and kidney injury in rat model of CCl4 through exerting anti-inflammatory and antioxidant activity. Fish oil/Nigella sative volatile oil emulsion was the most promising hepato-regenerative and reno-protective formula among the different groups.
- 著者
- Kuzmenko Alexander I. Niki Etsuo Noguchi Noriko
- 出版者
- 公益社団法人 日本油化学会
- 雑誌
- Journal of oleo science (ISSN:13473352)
- 巻号頁・発行日
- vol.50, no.6, pp.497-506, 2001-06-01
- 参考文献数
- 21
- 被引用文献数
- 13
The antioxidizig action of 20-hydroxyecdysone was investigated in several systems <I>in vitro</I>. Changes in the parameters of chemiluminescence in the presence of 20-hydroxyecdysone were found in rat liver mitochondrial fractions. The effect of 20-hydroxyecdysone on methyl linoleate micelles free radical oxidation was studied. The rate of oxygen uptake in methyl linoleate micelles was found to be smaller when 20-hydroxyecdysone was present than at its absence. The action of 20-hydroxyecdysone in the liposomal membranes oxidation was investigated be means of α-tocopherol consumption. A lower rate of α-tocopherol consumption in the oxidation of liposomal membranes was found when 20-hydroxyecdysone was present.<BR> The effect of cholesterol on free radical formation in liposomal membranes was investigated. The rate of free-radical formation was smaller when cholesterol was present in the membrane than in membranes free of cholesterol. The α-tocopherol antioxidant effect in the membrane was also lower when cholesterol was present. We show here for the first time that 20-hydroxyecdysone has an antioxidant action in combination with α-tocopherol in membranes with cholesterol overload. Kinetic measurements were revealed the 20-hydroxyecdysone antioxidant effect on free radical reactions in membranes.
- 著者
- Yoshimune Nonomura Momoka Sano Ryota Sekine Yoshiyuki Daikoku
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess21210, (Released:2021-11-09)
- 被引用文献数
- 2
Surface treatment of wood surface is an effective method to improve the physical properties. The friction dynamics of wood coated with vegetable oil were evaluated and compared to wood treated with polyurethane and untreated wood. The kinetic friction coefficient, µk, was 0.39±0.01, which was smaller than the values for polyurethane–treated wood and untreated oak. The effect of the surface treatment was also observed in the dependence of velocity on the friction coefficient. The friction profile of the wood surface treated with vegetable oil was similar to that of untreated wood, and the friction coefficient was nearly constant, except in the static friction region of sliding out. These results suggest that wood treated with vegetable oil is suitable for inducing a smooth feel.