著者
Junji ITO Hiroshi MORIYAMA Seiichiro INOKUCHI Noboru GOTO
出版者
オカジマ・フォリア・アナトミカ・ヤポニカ編集部
雑誌
Okajimas Folia Anatomica Japonica (ISSN:0030154X)
巻号頁・発行日
vol.80, no.2.3, pp.47-56, 2003 (Released:2008-01-18)
参考文献数
11
被引用文献数
13 30

Morphological study of the lower limb muscles is necessary for the analysis ofmuscle function and its relation to the aging process. In this study, we measured the muscle weight and the muscle fiber morphometry (cross-sectional area and total number of muscle fibers at the muscular belly, and muscle fiber size) of the human lower limb in an adult Japanese cadaver (male, 58 years old). The results presented here can provide the normal control data to elucidate the aging process of the human lower limb muscles. The morphological features in the human lower limb muscles were the pronounced enlargement of the gluteus maximus in the hip, the vasti muscles in the thigh and the soleus in the leg.
著者
Kin-ya KUBO Yukiko ICHIHASHI Chika KURATA Mitsuo IINUMA Daisuke MORI Tasuku KATAYAMA Hidekazu MIYAKE Shu FUJIWARA Yasuo TAMURA
出版者
オカジマ・フォリア・アナトミカ・ヤポニカ編集部
雑誌
Okajimas Folia Anatomica Japonica (ISSN:0030154X)
巻号頁・発行日
vol.87, no.3, pp.135-140, 2010 (Released:2012-02-10)
参考文献数
88
被引用文献数
5 21

Recent studies have suggest that masticatory (chewing) function is useful for maintaining neurocognitive function in the elderly. For example, a reduced ability to masticate, such as that resulting from toothlessness or soft-diet feeding, causes learning and memory deficits in aged animals and pathologic changes in the hippocampus. In addition, occlusal disharmony impairs hippocampal memory processes via chronic stress, and induces similar hippocampal pathology. Chewing, however, rescues stress-induced suppression of long-term potentiation in the hippocampus and the stress-induced impairment of hippocampal-dependent learning. These findings strongly suggest a link between mastication and neurocognitive function.
著者
Hideki OHNO Shunsuke GOTO Masao OWAKI Joji OHTA Naoshi NAKAJIMA Kaori NAKATA Ken-ichiro MUTOH Toshifumi OYAMADA Kazuki YOSHIOKA
出版者
オカジマ・フォリア・アナトミカ・ヤポニカ編集部
雑誌
Okajimas Folia Anatomica Japonica (ISSN:0030154X)
巻号頁・発行日
vol.90, no.2, pp.31-39, 2013 (Released:2013-10-10)
参考文献数
18
被引用文献数
1

Androgen is closely involved as the cause of rupture of anterior cruciate ligament (ACL) in human. In dogs, however, factors contributing to rupture of ACL remain unknown. In this study, expression of androgen receptor (AR) and histological distribution of blood vessels in ACL, and serum testosterone concentration were investigated in relation with age and sex to confirm whether canine ACL is an androgen-responsive tissue. Materials of ACL were obtained from 26 dogs: 12 young female Beagles, 2 old female mixed breeds, 9 young male Beagles, and 3 old male mixed breeds. In all canine ACL, positive AR expression was recognized in the nuclei of the fibrocytes, fibroblasts, synovial cells, and vascular endothelial cells of ACL. Expressions of AR were lesser in old males compared to the young males; however, females had no age difference in expression. Distributions of blood vessels in the synovial membrane of the ligament were fewer in old dogs both of males and females than youngs. Although distributions of vessels in the interstitium were apparently fewer in young females. Serum testosterone concentration was significantly higher in young males. Females had no age difference in the levels. From these results, it is suggested that canine ACL is an androgen-responsive tissue, and this consideration seems to closely relate to the epidemiological background that the incidence of rupture of ACL of dogs is higher in females than in males.
著者
Hideki OHNO Yoko KOWATARI Masao OWAKI Joji OHTA Naoshi NAKAJIMA Kazuki YOSHIOKA Ken-ichiro MUTOH Toshifumi OYAMADA
出版者
オカジマ・フォリア・アナトミカ・ヤポニカ編集部
雑誌
Okajimas Folia Anatomica Japonica (ISSN:0030154X)
巻号頁・発行日
vol.89, no.2, pp.35-38, 2012 (Released:2012-10-27)
参考文献数
10
被引用文献数
3 7

Anterior cruciate ligament (ACL) fibroblasts obtained from beagle dogs were cultured in basal medium containing different concentrations of 1 to 10-3 µM 5α-dihydrotestosterone (DHT) and in basal medium itself as a control. It was demonstrated that DHT promoted cell proliferation activity, expression of androgen receptor, and collagen synthesis in ACL fibroblasts as compared with control. These results suggest that sex hormones are involved in the sex difference seen in ACL rupture of dogs.