- 一般社団法人 日本アレルギー学会
- アレルギー (ISSN:00214884)
- vol.16, no.3, pp.178-222,225, 1967-03-30 (Released:2017-02-10)
In our series of 50 patients admitted to the Pediatric Department of Japanese Red Cross Central Hospital, Tokyo, from January of 1961 to November of 1966, its main clinical features were as follows: 1) All patients (50 cases) had temperature of 38 C. and more and its duration was at least 6 days in spite of antibiotics therapy. 2) In 49 (98%) of 50 cases bilateral injection of bulbal conjunctivae was seen. Pseudomembrane formation or corneal complication were not seen. 3) Forty-three cases (86%) of our series had skin eruption. The lesions were basely erythematous, appeared in whole body, especially in the plams and the soles, caracterized byno vesicle or bullous formations. 4) Forty-eight (96%) of 50 casesshowed dried, injected, eroded and fissurated lips, sometimes with bleeding and crust formation. Mucous-membrane of the mouth showed diffuse injection without any vesicle or aphtha formations. There were sometimes strawberry-tongue. 5) Thirty-three (66%) of 50 cases had acute non-suppurative crevical lymphadenitis which showed from thumb-tip to hens-egg and more in size. 6) Angioneurotic edema of hands and feet was seen 22 cases (44%) in infancy and small children. 7) Acrodesauqmation from the junction of the nail and skin on fingers and toes was seen in 49 cases (98%). It began to almost second week of illness. This desquamation limited in hands and feet, never seen in other parts of the body. 8) The age range was from 2-month-old to 9-year-and-1-month-old. Over half of patients, 27 cases (54%) was under 2-year-old. 9) This syndrome showed natural curability, no residual formation, no recurrency and no contagious tendency among siblings. From the clinical findings mentioned above this syndrome seemed to be a new clinical entity.