3 0 0 0 OA 脳と心

著者
糸川 昌成
出版者
The Philosophy of Science Society, Japan
雑誌
科学哲学 (ISSN:02893428)
巻号頁・発行日
vol.47, no.2, pp.53-68, 2014-12-20 (Released:2015-11-08)
参考文献数
18

Schizophrenia is severe mental disorder. A genetic study is thought to be effective to reveal pathophysiology of schizophrenia since genetic factors are involved in developing the disease. Molecular biology has been performed to detect etiology of the mental illness. However, genetic studies have not found a causative mutation from patients with schizophrenia because the psychotic illness is large heterogeneous syndrome, not homogeueous disease. Mind is depending upon central nervous systems but is not equal to the brain. We need to study on not only the brain but also the mind.

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統合失調症患者50例のドーパミンD2 受容体の遺伝子配列を解析し,11例から遺伝子配列の変化を発見した ドーパミンD2受容体は,443個のアミノ酸が連なっている.11例では遺伝子配列が変化した結果,311番目のアミノ酸(セリン)が別のアミノ酸(システイン)に置換していた https://t.co/vangbeWKdV

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