- 整形外科と災害外科 (ISSN:00371033)
- vol.37, no.1, pp.316-320, 1988-10-25 (Released:2010-02-25)
We have been reported the effects of some drugs (ex. calcitonine, vitamin D etc.) on epiphyseal growth plate of HEBP (EHDP) induced rachitic rats, but those effects may be characteristic for HEBP induced richets. So we started the study about strontium induced rachitic rats. In this paper, effects of calcium and strontium content in a diet on epiphyseal growth plates of rats were reported.Our results were as follows: 1) With the diet containing 2 weight % of strontium and 0.1 weight % of calcium for 3 weeks, remarkable rachitic changes of epiphyseal growth plate of the rat were evoked; 2) In this exprimental model, serum Pi and Ca decresed, and serum Alp incresed significantly compared with control.