著者

福地 義之助 原沢 道美 半田 昇 吉川 政己

出版者

The Japanese Respiratory Society

雑誌

日本胸部疾患学会雑誌 (ISSN:03011542)

巻号頁・発行日

vol.7, no.5-6, pp.266-271, 1969-12-31 (Released:2010-02-23)

参考文献数

11

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A case of chronic interstitial pulmonary fibrosis in a seventy two year old male was presented with pertinent clinico-pathological findings.The patient had worked in a shell ornament firm over fifty years when he developed exertional dypnea, cough and yellowish sputum. The chest X ray film taken at the time of his first visit to this clinic already showed diffuse bilateral linear and reticular shadow with partial conggregation. Pulmonary function study disclosed marked restrictive ventilatory disturbance and impairment of diffusion with mild hypoxemia. Dyspnea became progressively worse with each episode of recurrent respiratory infection, although supportive treatment with various antibiotics, bronchodilators and oxygen administration brought him temporal amelioration of symptoms. The patient eventually died of pulmonary insufficiency and heart failure secondary to intractable respiratory infection three years after the initial examination.Cardinal pathologic findings were chronic interstitial pneumonitis and cor plumonale which were compatible with clinical and laboratory data. Microscopic findings of the lung consisted of variable degrees of hyaline membrane formation, interstitial fibrosis and edema, chronic cellular infiltation, bronchiolectasis and abnormal proliferation of bronchiolar epithelium. These pathological changes were taken as rather indicative of chronic pneumonitis than established fibrosis. The significance of the patient's longstanding exposure to the shell dust was discussed in view of the etiology of so-called idiopathic interstitial pulmonary fibrosis and postulation for possible mechanism of its contribution to the development of those pathologic findings was made.

著者

小沢 利男 半田 昇 氏井 重幸 岸城 幸雄

出版者

一般社団法人 日本老年医学会

雑誌

日本老年医学会雑誌 (ISSN:03009173)

巻号頁・発行日

vol.16, no.6, pp.513-521, 1979-11-30 (Released:2009-11-24)

参考文献数

15

被引用文献数

1

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体重身長指数は身長との相関が少なく, 体重と相関が大であることを要する. この点について四つの指数I1=W/H (比体重, Wは体重, Hは身長), I2=W/H2 (Body Mass Index, BMI) PI=H/3√W (Ponderal Index), BK=W/(H-100)×0.9 (Broca-桂の指数) を検討した. 対象は10歳代から70歳代に及ぶ健常男子6,272名, 女子7,230名, 計13,502名である. その結果男女各年代層を通じてBMIが身長との相関が最も小さく, 体重との相関は比体重についで大であった. 又20歳代を対象として5cm毎に区分した各身長に対する各指数の変化をみると, BMIが最も一定した値を示した. 加齢に伴うBMIの変化をヒストグラムからみると, 男子では30歳代で20歳代より右に偏るが, その後60歳代に至るまでほぼ同じ分布を示した. 女子では20歳代から加齢と共に漸次右方に偏る傾向がみられた. 血圧との関係ではBMIの高いものに高血圧の出現頻度が高く, 特に男子でこの傾向が顕著であった. 男子における喫煙量とBMIとの間には一定の関係がみられなかった.