著者
木戸 和貴子 吉川 友佳子 中村 衣里 橋本 ゆかり 戸根 瑛美 松浦 寿喜
出版者
日本食品化学学会
雑誌
日本食品化学学会誌 (ISSN:13412094)
巻号頁・発行日
vol.19, no.3, pp.185-190, 2012-12-21 (Released:2017-01-27)
参考文献数
11

The inhibitory effects against hyperglycemia of "alleged health foods" containing mulberry leaves as an ingredient were compared using an experimental model of digestion and absorption in rats. Rats, after gastric and portal venous catheterization, were continuously fed an aqueous sucrose solution by intragastric administration, and portal venous glucose concentrations were maintained at a constant level. The rats were administered either five types of mulberry leaf tea or three types of mulberry leaf granules, and the time period during which the portal venous glucose concentration showed levels significantly lower than baseline, i.e., the duration of the inhibitory effect on hyperglycemia, was compared. The results showed that although all of these health foods demonstrated an inhibitory effect against hyperglycemia, a comparison of the efficacy based on the duration of this inhibitory effect revealed large disparities among the products, of a magnitude of 17-fold among the mulberry leaf teas and 11-fold among the granular mulberry leaf products. This discrepancy in the efficacy of these types of products could not be discerned by analogy based on the label or the ingredients described on the product. Although alleged health foods are ordinary foods, and efficacy is not demanded, a uniform level of quality assurance is necessary, given that the general consumer purchases these products in expectation of a certain level of effect.
著者
松浦 寿喜 吉川 友佳子 升井 洋至 佐野 満昭
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.124, no.4, pp.217-223, 2004-04-01 (Released:2004-03-27)
参考文献数
25
被引用文献数
17 22

The inhibitory effects on the intestinal digestion and absorption of sugar of health teas that claim beneficial dietary and diabetes-controlling effects were compared in rats using portal cannulae. The measured durations were the times during which the elevation of portal glucose levels resulting from continuous intragastric infusion of sucrose or maltose was suppressed by concentrated teas. The teas investigated included salacia oblonga, mulberry, guava, gymunema, taheebo, yacon, and banaba. The duration of the inhibitory effect on the sucrose load of salacia oblonga, mulberry, and guava were 110 min, 20 min, and 10 min, respectively. In contrast, gymunema, taheebo, yacon, and banaba had no significant effect on the continuous infusion of sucrose. These results suggest that there is considerable difference in the efficacy of commercial health teas in influencing glucose absorption.