著者
前川 隆彰 武 純也 河村 俊邦 堀内 俊克 加藤 章一郎 彦田 玲奈 山村 武史 渡邉 純一 小林 彩香 小林 真一 佐藤 謙 木村 文彦
出版者
The Japan Society for Hematopoietic Stem Cell Transplantation
雑誌
日本造血細胞移植学会雑誌 (ISSN:21865612)
巻号頁・発行日
vol.3, no.4, pp.114-119, 2014 (Released:2014-10-15)
参考文献数
15

HLA一致非血縁ドナーより同種骨髄移植を受けた46歳の原発性骨髄線維症の男性。移植後の血小板数は3×104/μl台で安定していたが,移植後199日目に感染や慢性移植片対宿主病(GVHD)を伴わず,急性の経過で0.7×104/μlまで低下した。好中球減少や貧血は認めず,末梢血のキメリズム解析では完全ドナー型を維持しており,二次性の生着不全は否定された。脾腫の増大も認めなかった。血小板輸血に反応せず,抗HLA抗体は陰性であったが,抗GPIIb/IIIa抗体が検出された。PAIgGの上昇も認め,免疫性血小板減少症(ITP)と診断した。prednisolone 1mg/kgで治療を開始し,治療開始7日目より血小板数が増加した。同種移植後のITPの多くはGVHD等が関与しており,しばしば治療抵抗性である。本症例は他の免疫反応を伴わず治療反応性も良好であった。病態を検討する上で重要な症例と考えたため,文献的考察を加え報告する。
著者
飯野 光喜 新津 恒太 堀内 俊克 松島 凛太郎 村上 夏帆 瀬戸 〓一 関谷 利子 中村 芳樹 桑原 洋助
出版者
THE JAPANESE SOCIETY FOR JAW DEFORMITIES
雑誌
日本顎変形症学会雑誌 = The Japanese journal of jaw deformities (ISSN:09167048)
巻号頁・発行日
vol.10, no.3, pp.273-280, 2000-12-15
参考文献数
22
被引用文献数
4 3

The accuracy of positioning the osteotomized maxilla during orthognathic surgery was assessed in 26 patients, comparing the use of an external reference point placed on the forehead skin (SERP), and an external reference point consisting of a bone screw placed at the forehead bone (BERP). In all cases, the unoperated mandible was used to provide an anteroposterior and transverse maxillary position, through use of an intermediate splint. In 14 cases, the distance between the SERP and the maxillary central incisor was measured, to determine the maxillary vertical dimensions. In 12 cases, measurements between the BERP the and maxillary central incisor were made.<BR>All preoperative lateral cephalometric radiographs were traced by one investigator, and these tracings were superimposed on postoperative lateral chephalograms (3 to 6 days after surgery), respectively. The actual changes in the vertical and horizontal position of U1 were measured perpendicular and parallel to the Frankfort horizontal plane. The actual change of the palatal plane angle was also measured. These values of actual change were compared with the prediction tracings made by measurements obtained from model surgery, and the difference between planned and actual movements was calculated.<BR>The mean difference of U1 anteroposterior movement was 1.5±2.0mm in the SERP group, and 1.2±1.1 mm in the BERP group. The mean difference of U1 vertical movement was 1.8 ±2.8mm in the SERP group, and 0.5±0.3mm in the BERP group. And the mean difference of palatal plane angle rotation in the SERP group was 2.7±6.2°, and 1.6±1.8° in the BERP group. Statistical analysis showed a significant difference between the SERP group and the BERP group in the U1 vertical difference (t-test, p<0.05).<BR>The results of this investigation revealed less accuracy in the actual three-dimensional maxillary movements of the SERP group, compared with the BERP group. And this study also showed that use of the BERP will allow accurate three-dimensional control of the maxillary position, especially in the vertical dimension. However, the maxillary repositioning technique using BERP still remains subject to operator error, and other numerous possible sources of error were identified, which may lead to an incorrect result.