著者
上野 雅代 前原 加奈子 吉住 亜紀子 池内 忠宏 真島 宏太 山本 知佳 DennisM. Williams 二神 幸次郎
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.34, no.9, pp.882-890, 2008 (Released:2010-02-07)
参考文献数
16
被引用文献数
3

Smoking is a risk factor for pulmonary diseases,cardiovascular diseases and many other morbid conditions but it is difficult to get patients to cease smoking due to the strength of nicotine dependence.As one of our pharmaceutical management and counseling services,we conducted a smoking cessation intervention program for inpatients in which we counseled them on the proper use of nicotine replacement products using a smoking cessation guidebook,and evaluated the usefulness of such counseling.We interviewed 228 patients and from among them enrolled 18 current smokers and 11 people who had stopped smoking during the past 30 days as subjects.The content of the program was evaluated through a questionnaire survey of patients and the success of the counseling by pharmacists was evaluated by smoking cessation status at discharge.Immediately after the program,44.4% of the smokers had ceased smoking and this figure had increased to 83.3% at the time of discharge.All subjects who had stopped smoking during the past 30 days continued to refrain from smoking until discharge.The results of the questionnaire survey showed that the use of a smoking cessation guidebook in the intervention enhanced awareness of the importance of ceasing smoking in 89.7% of the subjects.Though they were frequently made aware of nicotine replacement products,only about 10% had wished to use them.The findings of the questionnaire survey suggest that our smoking cessation intervention program for inpatients involving counseling on the proper use of nicotine replacement products improved patients’awareness of the importance of smoking cessation and reduced the smoking rate.
著者
芝口 浩智 山本 知佳 黒木 政秀 二神 幸次郎
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.130, no.7, pp.977-982, 2010 (Released:2010-07-01)
参考文献数
13
被引用文献数
1 4

Cytomegalovirus (CMV) remains the most important pathogen following solid organ transplantation and is the major cause of recipient morbidity and mortality during the first 6 months posttransplantation. To prevent CMV infection and/or to prevent symptomatic CMV disease, immunoglobulin (Ig) G including hyperimmune CMV IgG are used alone or in combination with antiviral medications. The CMV IgG titer, however, has a wide range and frequently depends on the company supplying the Ig preparation even if the preparations come from the plasma pool of a national blood donation agency. In the present study, we therefore simultaneously measured and evaluated the CMV IgG titers in various Ig preparations using two common methods: the neutralizing antibody (NT) and enzyme immunoassay (EIA). The CMV IgG titer in the present study indicated different values using both methods among Ig preparations that were made from the plasma pool of a national blood donation agency (about 3.5- or about 1.7-fold difference using the NT or EIA methods, respectively). Furthermore, there were no correlations in the CMV IgG titer between our findings and published data from the manufacturers, or between the two methods tested here. These findings suggest the importance and necessity of a standard method and/or sample for the measurement and assessment of CMV IgG in Ig preparations.