著者

小山 善之 熊取 敏之 澁谷 敏三 新谷 和夫 福田 龍三 今村 幸雄 佐野 一郎 鴫谷 亮一 古屋 曉一 河野 實 日野 佳弘 渡邊 孝 武正 勇造 中村 なをゑ 小澤 義光 林 康之 平島 信子 早船 喬一 濱口 榮祐 木村 信良 神田 清 岡本 十二郎 濱田 政彦 大橋 成一 橋本 敬祐 小酒 井望 石井 暢 天木 一太 深澤 義明 貴船 トミ子 松村 義寛 中野 巖 種田 強一郎 林 義次 村田 貢

出版者

Japanese Society of National Medical Services

雑誌

医療 (ISSN:00211699)

巻号頁・発行日

vol.9, no.1, pp.5-45, 1955

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This paper is an intermediate report of the clinical observations and various investigations made upon the 16 patients of the radiation sickness caused by BIKINI ashes on. 1st March 1934. The patients were admitted to the First Tokyo National Hospital on March 28th, and this report shall be for the period of the 5 months from March 28th to the end of August, 1964. Later, a thorough and complete report will be given, in which some amendments may be added to the present paper.<br>INTRODUCTION: At 3.50 a. m. on 1st March 1954, the 5th Lucky Dragon, a fishing boat, with a crew of twenty three on board, was located at about 100 miles east of BIKINI. The boat was under grey-white ash-fall for more than 5 hours. The crew was exposed to the ash-fall for 1.5 to 5 hours. The evening of that day they suffered from headache, anorexia, conjunctivitis and later nausea, vomiting, exhaustion and diarrehea, Several days later they suffered from itching, pain, rash, and erosion on the exposed skin areas. One week later two of the crew had hemorrhage of gingiva and some of the crew suffered from depilation. On March 19th, the boat returned to its base at Yaizu. On March 16th, the crew was admitted to the Kyoritsu Yaizu Hospital and on March 28th, 16 patients out of 23 were transfered to our hospital (the First Tokyo National Hospital).<br>On March 26th, Prof. Kimura's laboratory of Tokyo University made the analysis of the ashes taken from the 5th Lucky Dragon and found the following radioactive substances: Sr-89, Sr-90, Y-90, Y-91, Zr-96, Nb-95m, Nb-95, Ru-103, Ru-106, Te-129m, Te-129, Te-132, I-131, I-132, Ba-140, La-140, Ce-141, Ce-144, Pr-143, Pr-194, Nd-147, Pm-147, S-35, Ca-45, U-237, and Pu-239. The remaining radiation of the boat was investigated by Dr. Kakei et al. of March 17th and found it to be around 100mr/hr. Upon this data the total radiation was estimated at a count of 270 to 440γ. on the crew. In addition to the external exposure of such radiation, internal exposure, such as respiration of contaminated air, drinking of contaminated water and taking of contaminated food, shall be taken into consideration in the present cases. Radioactivity was found in the bile and urine taken from the patients.<br>GENERAL REMARKS: The 16 cases were strong young men but their body weight began to decrease from the middle of May and high or slight fever, anorexia, feeling of exhaustion, diarrhea and headache continued.<br>Skin and Hair: Irregular depilation, depigmentation, pigmentation with rain and itching, and erosion was observed. Some cases had folliculitis with pustules in April, while others recovered from erosions and at the end of May, regeneration of hair began. In July, hair condition was almost normal.<br>Blood and Bone-marrow: At the middle of April, the lowest peripheral leucocyte count was less than 2, 000. Two cases who had lower leucocyte count recovered earlier, i. e., their leucocytes increased to around 5, 000 at the middle of May. Meanu hile, the other cases had from 3, 033 to 4.000 count during the entire period. The former cases had also moderate anemia while the latter had only slight anemia. Blood platelet count of the former cases was less than 20, 000 and the recovery was slower than that of the leucocyte count. Reticulocyte count kept pace with that of leucocyte. In the former cases, myelocyte and other immature blood cells appeared temporarily in the circulated blood and eosinophile cells increased. The count of bone-marrow cells decreased remarkably (8, 000), i. e. panmyelophthisis, which later recovered slowly. In the latter cases, peripheral leucocyte findings and myelogram had almost no changes from the beginning of our observation and count of bone marrow cells was remarkably different by the sites of bone-marrow puncture. Vacuole and toxic granula appeared in the neutrophile cells in the circulated blood and vacuoles also appeared in lymphocyte and monocyte.

著者

田村 瑞枝 山本 貴嗣 石井 太郎 萩原 徹 斎藤 正樹 服部 研吾 久山 泰 宮本 博文 小田中 佳子 加藤 洋司 新谷 和夫 松井 浩 杉下 靖郎 小田 福美

出版者

公益社団法人 日本人間ドック学会

雑誌

健康医学 (ISSN:09140328)

巻号頁・発行日

vol.16, no.3, pp.249-253, 2001-11-30 (Released:2012-08-27)

参考文献数

13

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無症状の人間ドック受診者242人を対象に,尿中抗Helicobacter pylori抗体(ウリネリザ)を測定し血中抗体法と比較したところ,良好な一致率であった。内視鏡的検査を基準とした場合,ウリネリザの診断能は血中抗体法とほぼ同等であった。またウリネリザ陽性群では陰性群と比較して,上部消化管の有所見率が高い傾向が認められ,上部消化管のスクリーニングの一法として有用である可能性が示唆された。