著者
木村 三生夫
出版者
一般社団法人 日本小児神経学会
雑誌
脳と発達 (ISSN:00290831)
巻号頁・発行日
vol.3, no.2, pp.113-118, 1971-03-01 (Released:2011-05-24)
参考文献数
13

During 1967 to 1970, 65 cases of postvaccinal central nervous system diseases were reported to Smallpox Vaccination Committee.Among these, 40 cases were classified as postvaccinal encephalitis or encephalopathy. Incubation periods of these cases were between 4 to 17 days (mean 8.7 days). 31 cases were under 1 year of age, 8, 1 year and 1, 12 years of age, respectively. These case distribution accounted for age were thought to be paralleled to age distribution of smallpox vaccination performedThough it would be often difficult, from the clinical grounds, to distinguish encephalopathy from encephalomyelitis, 14 cases were thought to be typical encephalopathy, and many of the others showed only slight cerebrospinal fluid abnormality. It was suggested that the clinical manifestations of those very young children were belonged to encephalopathy.The prognosis were relatively good, 20 were completely recovered, 3 died and 16 left central nervous system sequeles. It was thought that few severe or fulminant cases were reported here.The other types reported were, mild transient encephalopathy 3, acute infantile hemiplegia, 3, aseptic meningitis type, 11, myelitis, 1 and neuropathy, 2.