著者

池田 苗夫

出版者

社団法人 日本感染症学会

雑誌

日本傳染病學會雜誌 (ISSN:00214817)

巻号頁・発行日

vol.42, no.5, pp.125-130, 1968-08-20 (Released:2011-11-25)

---

As mentioned in previous reports, it was clear that the epidemic hemorrhagic fever (EHG) could be induced to quite healthy persons by inoculation of the blood specimens collected from the patients with genuine EHF. Therefore, the agents of EHF were certainly considered to exist in the blood of patients in acute stage of EHF.Dr. Masaji KITANO found a specific species of tick, ‘Togedani’, attaching to rat and playing an important role as a carrier of the disease, and so he insisted that the togedani inhabiting the areas where, EHF was prevelent, might be a natural possessor of the agents. In addition, it was supposed that in such circumstances, other insects such as vermin, fleas, bed-bugs, flies, or mosquitoes might be also reservor of the agents at least transiently. However, because no soarlling blood-sucking insects could remain being active in serious cold of winter in the noreheastern part of China where EHF had been prevalent still in this season, these kinds of insects could be excluded from the object of investigation. The author examined the infectivity of fleas and lice isolated from patients, and acquisition of infectivity on the artificially incubated unstained louse line by stinging the patients with EHF. Thus, it was confirmed that the healthy persons would develop the disease by stinging of poisoning louse.It is not clear whether lice in the epidemic area naturally possess the agents of EHF, but it is doubtless that the poisoning lice which have sucked the blood from a healthy person, may cause him an infection of EHF. Therefore, it is concluded that a louse must be looked upon as a carrier of EHF.On the other hand, as to the flea, the author failed to confirm whether flea had infectivity of EHF to man, in consequence of several biological experiments.

著者

池田 苗夫

出版者

社団法人 日本感染症学会

雑誌

日本傳染病學會雜誌 (ISSN:00214817)

巻号頁・発行日

vol.42, no.4, pp.75-77, 1968-07-20 (Released:2011-11-25)

---

Several serlogical experiments were carried out to establish a serum reaction specific to epidemic hemorrhagic fever in man.The results were as follows:1. Unchanging low precipitating antibody titers in patient sera against supernatant fluid of emulsion of liver released from deceased patient by autopsy, suggested that the reactiossn failed to be a useful method for the diagnosis.2. The Weil-Felix antibodies in sera from patients in pyrexial stage, to the Proteus vulgaris OX-19, OX-2, and OX-K strains, were also so low that the Weil-Felix reaction was not specific for the disease.3. Finally, a skin test with antigenic materials prepared by filtrating the liver emulsion in physiological saline solution (as well Ringer's solution or Tyrode's solution) with Chamberland filter, was performed and it was demonstrated that this reaction was useful to differentiate the patients from the controls with other diseases after 24 hours and therefore available for the diagnostic purposes.

著者

池田 苗夫

出版者

社団法人 日本感染症学会

雑誌

日本傳染病學會雜誌 (ISSN:00214817)

巻号頁・発行日

vol.41, no.9, pp.337-346, 1967-12-20 (Released:2011-11-25)

参考文献数

5

---

Tamura reported that there has fairly long been existing epidemic haemorrhagic fever (EHF) in Osaka City in the form of an endemic and there is likely to be a great possibility of its spreading to other parts of this country. This motivated the author to make public his experience with this disease in northern and eastern Manchuria at the time when he was a member of the special medical team of the then Japanese Imperial Army.Since 1938, Japanese army had begun stricken by a hitherto unknow disease in northern and eastern Manchuria. At an outbreak in Songo and Sanchinfu, northern Manchuria, in winter of 1941, the number of patients including soldiers and villagers counted as many as 500. Mortality rate of this epidemic was. aboto. the recuthout 15%. Later, in 1942, the special medical team, before mentioned, was set up and dispatched epidemic areas. The discovery of EHF was thus brought about by them in that year. The firstognition of its viral and infectious nature was made through an experiment carried out by the ar

著者

池田 苗夫

出版者

一般社団法人 日本感染症学会

雑誌

感染症学雑誌 (ISSN:03875911)

巻号頁・発行日

vol.48, no.4, pp.131-138, 1974-04-20 (Released:2011-09-07)

---

1) A special hemogram: red cells have tendency to increase at the earlyphase and decrease after haemorrhagic phase; in the acme appeared reticulocyte; generally hemogrobin has decreasing tendency. White blood cells show a slighly decrease in the beginning, but increase at the pyrogenetic stage (febriletime); early in the second day of the pyretolysis or late in the several days return to normal. In the leucocyte analysis, the increase of the neutrophile leucocyte was seen; a marked shift to the left is noted in the beginning; myelocyte and metamyelocyte at times appear; mean nuclei counts show a high value 1.5-2.0; distinct vacuolated leucocyte and toxic granules are present in the pyrogenetic stage and the acme. The appearing and disappearing of eosinophile leucocyte are not distinct like typhoid disease. Mononuclear leucocytes and plasmacells a little increase; basophile leucocytes are present in the beginning, but basophile leucocytes are hardly seen in the acme; the platelet number decreases from the beginning and then increases and return to normal but in the patient of grave prognosis the counts remain low. I indicate the thrombopenie as a prognostically important factor of the Epidemic Hemmorrhagic Fever.2) Urinalysis: urobilinogen and urobilin or Diazo tests showed questionable results, but Indican test at times was positive. On the convarescence, the amount of the urine increased and urinary albumin and casts and flocks disappeared.

著者

池田 苗夫

出版者

社団法人 日本感染症学会

雑誌

日本傳染病學會雜誌 (ISSN:00214817)

巻号頁・発行日

vol.42, no.6, pp.157-160, 1968-09-20 (Released:2011-11-25)

参考文献数

6

---

The author described some results of ecological studies on body lice, which he hadartificially bred and incubated. Namely, he observed their life cycle and several important habits, established unstained louse strains, and using them, determined the optimum coditions, especially temperature of incubation or blood-stinging intervals, to breed and maintain them.

著者

池田 苗夫

出版者

一般社団法人 日本感染症学会

雑誌

感染症学雑誌 (ISSN:03875911)

巻号頁・発行日

vol.51, no.2, pp.59-61, 1977-02-20 (Released:2011-09-07)