31 0 0 0 OA 服薬拒否小児のコンプライアンス向上のための市販菓子用即時型ゲル基剤の臨床応用
- 著者
- 虎石 顕一 中村 規子 由井薗 陽一 森 真弓 山田 正紀 高橋 司 黒川 美智子
- 出版者
- 一般社団法人 日本医療薬学会
- 雑誌
- 病院薬学 (ISSN:03899098)
- 巻号頁・発行日
- vol.24, no.5, pp.479-483, 1998-10-10 (Released:2011-08-11)
- 参考文献数
- 12
- 被引用文献数
- 12 9
In order to improve children's compliance in taking bitter medicine, a gel base confectionery, which immediately changes into a jelly from after adding a special liquid, was used to mask the characteristic taste of the medicament. In pre-clinical trials, this jelly was evaluated by six adult volunteers who all reported the bitter taste to distinctly disappear in the jelly-formed quinia compared to a the powder of this medicine. Furthermore, we confirmed no comparable changes to exist in the serum levels of acetaminophene between acetaminophene alone and the gelbasemedicament mixture by oral administration. A clinical trial in three pediatric patients, who usually refuse medication because the bitter taste of the drugs, resulted in a 100% drug compliance for these children.
1 0 0 0 インスリン注入器の第一印象と手技体験後印象の比較調査
- 著者
- 中野 玲子 武藤 達也 虎石 顕一 朝倉 俊成
- 出版者
- 日本医療薬学会
- 雑誌
- 医療薬学 (ISSN:1346342X)
- 巻号頁・発行日
- vol.34, no.7, pp.705-710, 2008-07-10
To clarify the factors in preference for insulin injectors, 69 subjects (aged 20-49 years) were asked to select 1 of 4 different injectors and then to complete a questionnaire regarding 9 selection factors regarded as important, among them "ease of gripping" and "portability" , before and after instruction on operating the injectors. "Portability" was considered the most important factor for selecting injectors on first impression, i.e. before instruction, and the percentage of subjects choosing "simplicity of operation" increased after instruction. About half of the subjects selected a different injector before and after instruction, so there appeared to be a relationship between injector selection and the evaluation factors. From the results, we made a table which we thought would be helpful in selecting insulin injectors based on factors regarded as important when using them in practice.