著者
青野 要 山本 道夫 飯田 荘介 内海 耕慥
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.90, no.9-10, pp.1297-1308, 1978-10-30 (Released:2009-08-24)
参考文献数
36
被引用文献数
1

In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes in vitro, several inducements of membrane lipid peroxidation and protective effects of V. E and SOD were investigated. Results obtained were as follows:(1) K+-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K+-release were protected remarkably by V. E and evidently by SOD.(2) Mitochondrial Fe2+ induced and Fe3+-O2 generating system - ADP induced lipid peroxidation, and microsomal O2 generating system - induced lipid peroxidation were also protected by V. E and SOD.(3) Radiation of X-ray or 60Co γ-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V. E and SOD.These results suggest that O2 and/or OH·generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis.
著者
早瀬 康博 花田 孝二 片岡 久美子 秋田 和俊 佐藤 眞 藤木 知一 岸 幹二 青野 要
出版者
特定非営利活動法人 日本歯科放射線学会
雑誌
歯科放射線 (ISSN:03899705)
巻号頁・発行日
vol.27, no.1, pp.10-16, 1987-06-22 (Released:2011-09-05)
参考文献数
38

Thermography was clinically applicated in 155 cases of various diseases in oral-maxillo-facial region. An attempt was made to evaluate the detectability of thermogram compared with the one of radiographic examination, the distribution of difference of temperature in various disease, the relationship between pain and the difference of temperature and the relationship between pain after operation and temperature change. Thermography was able to detect the influence of the lesions in soft tissue which was not detectable by radiograph. Thermographic findings was quite in accord with those of clinical symptom but not always with radiographic findings. In the cases of acute inflammation the difference of temperature with the opposite side showed wide range of distribution correlated with clinical symptom. In the cases of chronic inflammation no apparent difference was observed in the range of temperature. In cystic lesions without any acute inflammation the area of lesion was demonstrated as a cold spot. In cases of malignant tumor the area was shown as a hot spot between 0.5°C and 1.5°C In the cases of arthrosis painful areas were shown as localized hot spots. Correlationship was observed between pain and the differences of temperature and it was suggested that thermography might represent the painful area as an objective sign. It was also possible to demonstrate the changes of pathological conditions after operation by using thermography in lapse of time and it was indicated that thermography yielded much useful data as an excellent functional analyzing method.
著者
青野 要 山本 道夫 飯田 荘介 内海 耕慥
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.90, no.9, pp.1297-1308, 1978
被引用文献数
1

In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes <i>in vitro</i>, several inducements of membrane lipid peroxidation and protective effects of V. E and SOD were investigated. Results obtained were as follows:<br>(1) K<sup>+</sup>-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K<sup>+</sup>-release were protected remarkably by V. E and evidently by SOD.<br>(2) Mitochondrial Fe<sup>2+</sup> induced and Fe<sup>3+</sup>-O<sub>2</sub> generating system - ADP induced lipid peroxidation, and microsomal O<sub>2</sub> generating system - induced lipid peroxidation were also protected by V. E and SOD.<br>(3) Radiation of X-ray or <sup>60</sup>Co &gamma;-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V. E and SOD.<br>These results suggest that O<sub>2</sub> and/or OH&middot;generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis.