著者

Masaki Yoshioka Keisei Kosaki Masahiro Matsui Shoya Mori Natsumi Nishitani Chie Saito Kunihiro Yamagata Makoto Kuro-o Seiji Maeda

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ22-0063, (Released:2022-09-03)

被引用文献数

3

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Fibroblast growth factor-23 (FGF23) is a phosphaturic hormone secreted by the bone in response to dietary phosphate intake. Since the phosphate content in the diet correlates with the protein content, both plant- and animal-based protein intake can increase the serum FGF23 level. However, a higher percentage of energy from plant protein than from animal protein is associated with a lower serum FGF23 level in patients with chronic kidney disease (CKD) in the United States. Since dietary habits differ between Asian and Western populations, we performed a cross-sectional study to determine the association between the percentages of energy from plant and animal proteins and the serum FGF23 level in Japanese CKD patients. In 107 non-dialysis CKD patients (age: 66 ± 9 years; estimated glomerular filtration rate: 56 ± 21 mL/min/1.73 m2), the percentages of energy from plant and animal proteins were assessed using a food frequency questionnaire based on food groups. Venous blood samples were used to measure the serum FGF23, phosphate, 1,25-dihydroxyvitamin D, and intact parathyroid hormone levels. The percentages of energy from plant and animal proteins showed a negative and positive association, respectively, with the serum FGF23 level. Furthermore, isocaloric substitution modeling showed that replacing animal protein with plant protein was associated with a low serum FGF23 level. Our findings suggest that encouraging diets with high plant protein level may prevent an increase in the serum FGF23 level in Japanese CKD patients.

著者

齋藤 千恵 Chie SAITO 鈴鹿国際大学 Suzuka International University

雑誌

鈴鹿国際大学紀要Campana = Suzuka International University journal campana (ISSN:13428802)

巻号頁・発行日

vol.15, pp.45-63, 2009-03-20

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The 2004 Indian Ocean Tsunami devastated Aceh, Indonesia. Tsunami remarks and experiences have created a variety of narratives. A leaflet of tsunami tourism issued by the Indonesian government is one of them. Through an analysis of the leaflet, this paper examines what meanings the sate gives the disaster and Acehnese tsunami experiences and how it depicts the past and future of their society in an elaborate Islamic context. I also discuss an implied meaning of the Acehnese independent struggle ended by the tsunami.