- 著者
-
Madoka NAKAJIMA
Shigeki YAMADA
Masakazu MIYAJIMA
Kazunari ISHII
Nagato KURIYAMA
Hiroaki KAZUI
Hideki KANEMOTO
Takashi SUEHIRO
Kenji YOSHIYAMA
Masahiro KAMEDA
Yoshinaga KAJIMOTO
Mitsuhito MASE
Hisayuki MURAI
Daisuke KITA
Teruo KIMURA
Naoyuki SAMEJIMA
Takahiko TOKUDA
Mitsunobu KAIJIMA
Chihiro AKIBA
Kaito KAWAMURA
Masamichi ATSUCHI
Yoshihumi HIRATA
Mitsunori MATSUMAE
Makoto SASAKI
Fumio YAMASHITA
Shigeki AOKI
Ryusuke IRIE
Hiroji MIYAKE
Takeo KATO
Etsuro MORI
Masatsune ISHIKAWA
Isao DATE
Hajime ARAI
The research committee of idiopathic normal pressure hydrocephalus
- 出版者
- The Japan Neurosurgical Society
- 雑誌
- Neurologia medico-chirurgica (ISSN:04708105)
- 巻号頁・発行日
- vol.61, no.2, pp.63-97, 2021 (Released:2021-02-15)
- 参考文献数
- 286
- 被引用文献数
-
88
211
Among the various disorders that manifest with gait disturbance, cognitive impairment, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance. The first edition of these guidelines for management of iNPH was published in 2004, and the second edition in 2012, to provide a series of timely, evidence-based recommendations related to iNPH. Since the last edition, clinical awareness of iNPH has risen dramatically, and clinical and basic research efforts on iNPH have increased significantly. This third edition of the guidelines was made to share these ideas with the international community and to promote international research on iNPH. The revision of the guidelines was undertaken by a multidisciplinary expert working group of the Japanese Society of Normal Pressure Hydrocephalus in conjunction with the Japanese Ministry of Health, Labour and Welfare research project. This revision proposes a new classification for NPH. The category of iNPH is clearly distinguished from NPH with congenital/developmental and acquired etiologies. Additionally, the essential role of disproportionately enlarged subarachnoid-space hydrocephalus (DESH) in the imaging diagnosis and decision for further management of iNPH is discussed in this edition. We created an algorithm for diagnosis and decision for shunt management. Diagnosis by biomarkers that distinguish prognosis has been also initiated. Therefore, diagnosis and treatment of iNPH have entered a new phase. We hope that this third edition of the guidelines will help patients, their families, and healthcare professionals involved in treating iNPH.