著者
Yusuke Kubo Masae Ikeya Shuhei Sugiyama Rie Takachu Maki Tanaka Takeshi Sugiura Kaori Kobori Makoto Kobori
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.35, no.2, pp.93-98, 2023 (Released:2023-02-01)
参考文献数
30

[Purpose] Severe quadriceps weakness immediately after total knee arthroplasty can be problematic. The n-3 long-chain polyunsaturated fatty acids have antioxidant and anti-inflammatory effects against ischemia–reperfusion injury, whereas n-6 long-chain polyunsaturated fatty acids exert pro-inflammatory effects, thereby promoting ischemia–reperfusion injury. [Participants and Methods] We explored the efficacy of preoperative n-3 long-chain polyunsaturated fatty acid supplementation against early quadriceps weakness among 20 patients scheduled for total knee arthroplasty (intervention group, n=10; control group, n=10). The intervention group received 645 mg of eicosapentaenoic acid) and 215 mg of docosahexaenoic acid daily for 30 days preoperatively. Serum eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid levels were measured preoperatively. We compared serum derivatives of reactive oxygen metabolites as oxidative stress biomarkers, knee circumference, thigh volume, knee pain during the quadriceps strength test, and quadriceps strength preoperatively and 4 days postoperatively to quantify the change. [Results] Preoperative n-3 long-chain polyunsaturated fatty acid supplementation significantly increased the (eicosapentaenoic acid+docosahexaenoic acid)/arachidonic acid ratio in the intervention group. A significantly lower increase in quadriceps weakness was exhibited in the intervention group than in the control group. However, changes in oxidative stress, knee/thigh swelling, and knee pain during strength testing did not significantly differ between the two groups. [Conclusion] Preoperative n-3 long-chain polyunsaturated fatty acid supplementation exhibited beneficial effects on quadriceps weakness immediately after total knee arthroplasty.
著者
Hisashi Koshino Toshihiro Hirai Yoshifumi Toyoshita Yuichi Yokoyama Maki Tanaka Kazuo Iwasaki Toshio Hosoi
出版者
Japan Prosthodontic Society
雑誌
Prosthodontic Research & Practice (ISSN:13477021)
巻号頁・発行日
vol.7, no.1, pp.12-18, 2008 (Released:2008-02-22)
参考文献数
17
被引用文献数
19 40

Purpose: The purpose of this study was to reduce the number of food items for ease of use, and to eliminate the influence of food preferences (likes and/or dislikes) on an earlier version of the food intake questionnaire method for evaluating the ability of mastication in complete denture wearers which had been previously developed by the authors.Methods: The subjects were 262 complete denture wearers (average age: 76.7±6.1 years old, male: 128 persons, female: 134 persons). The food intake questionnaire composed of a list of 35 food items which were used in the study. All subjects were asked to assign a mark to each type of food according to one of five categories (easily eaten, eaten with difficulty, cannot be eaten, do not eat because of dislike, have not eaten since starting to wear dentures). In order to reduce the number of the initial 35 food items in the questionnaire, the correlation coefficient of the masticatory score, representing the masticatory ability before and after elimination of foods, was examined in all the subjects. The masticatory performance (MP) was also evaluated by a sieving method in all subjects.Results: In the questionnaire with 5 categories composed of 25 foods, the reliability coefficient (Cronbach’s α) was 0.939. There was significant correlation between the masticatory score using the 35 food item list and the new masticatory score using the new 25 food item list (r=0.95, P<0.01). There was significant correlation between the MP using the sieving method and the N-MS using the 25 food item list (r=0.62, P<0.01).Conclusion: It was confirmed that the new food intake questionnaire method, with a revised 25 food item list, was both valid and reliable.