- 著者
- Hiroaki Shimokawa Tomohiko Shindo Aiko Ishiki Naoki Tomita Sadamitsu Ichijyo Tasuku Watanabe Takashi Nakata Kumiko Eguchi Yoku Kikuchi Takashi Shiroto Jun Takahashi Satoshi Yasuda Hiroyuki Arai
- 出版者
- Tohoku University Medical Press
- 雑誌
- The Tohoku Journal of Experimental Medicine (ISSN:00408727)
- 巻号頁・発行日
- pp.2022.J078, (Released:2022-09-15)
- 被引用文献数
- 9
- 著者
- Naoki Tomita Yasuko Iwami
- 出版者
- 日本鳥学会
- 雑誌
- ORNITHOLOGICAL SCIENCE (ISSN:13470558)
- 巻号頁・発行日
- vol.15, no.1, pp.95-98, 2016 (Released:2016-02-05)
- 参考文献数
- 20
- 被引用文献数
- 5
We observed three Sand Martin Riparia riparia repeatedly attempting to copulate with a dead bird lying face down on the ground, with its wings spread and lowered. One of the three remained on the ground close to the dead bird and guarded it against copulation from the other two birds. Then, the guarding bird itself attempted to copulate with the dead bird. Based on subsequent dissection the dead Sand Martin was identified as an adult male. Based on our observations, we propose that the observed homosexual necrophilia may be partly explained by the absence of sexual dimorphism in this species and the posture of the dead martin. We suggest that posture is an important trigger arousing male sex drive in a sexually monomorphic species.
- 著者
- Naoki Tomita Yuichi Mizutani Philip N Trathan Yasuaki Niizuma
- 出版者
- The Ornithological Society of Japan
- 雑誌
- ORNITHOLOGICAL SCIENCE (ISSN:13470558)
- 巻号頁・発行日
- vol.14, no.1, pp.3-11, 2015 (Released:2015-02-18)
- 参考文献数
- 46
- 被引用文献数
- 8
Various seabird foraging strategies during the non-breeding season have recently been revealed by combining the use of bio-logging devices and the study of stable isotopic signatures (δ15N and δ13C) from various tissues. In this study, we used these combined methods to determine the relationships between stable isotopic signatures in Black-tailed Gulls Larus crassirostris primary feathers and the areas in which the feathers are presumed to have been grown. The fifth primary (P5) feathers are replaced during late August, and although the migratory movements for seven of the eight gulls studied during this replacement period differed, the isotopic δ15N and δ13C values were similar. These values indicated that the seven gulls fed on a wide range of prey from krill to demersal fish species. The isotopic values from P5 for the individual gull that moved southward after breeding, were much higher than for the seven other birds. In contrast, all eight gulls showed a relatively narrow distribution during the replacement of their outermost primaries (P10), which were replaced during mid October and November. However, the isotopic values from P10 of the individual that moved southward during replacement of P5 were also much higher. The unique isotopic values of this gull might indicate specialization in anthropogenic food resources or high trophic level resources through the migration period, regardless of location. Contrary to previous studies, our research did not detect links between migratory movements and stable isotopic signatures from feathers in Larus gulls migrating through a relatively narrow range and having considerable individual variation in diet.
- 著者
- Hiroaki Shimokawa Tomohiko Shindo Aiko Ishiki Naoki Tomita Sadamitsu Ichijyo Tasuku Watanabe Takashi Nakata Kumiko Eguchi Yoku Kikuchi Takashi Shiroto Jun Takahashi Satoshi Yasuda Hiroyuki Arai
- 出版者
- Tohoku University Medical Press
- 雑誌
- The Tohoku Journal of Experimental Medicine (ISSN:00408727)
- 巻号頁・発行日
- vol.258, no.3, pp.167-175, 2022 (Released:2022-10-25)
- 参考文献数
- 30
- 被引用文献数
- 9
The prevalence of Alzheimer’s disease (AD) has been rapidly increasing worldwide. We have developed a novel angiogenic therapy with low-intensity pulsed ultrasound (LIPUS), which is effective and safe in animal models of AD and vascular dementia. We performed two trials of LIPUS therapy for AD (mild cognitive impairment due to AD and mild AD); a roll-in open trial for safety, and a randomized, double-blind, placebo-controlled (RCT) trial for efficacy and safety. The LIPUS therapy was performed for whole brain through the bilateral temporal bones for one hour 3 times a week as one session under the special conditions (1.3 MPa, 32 cycles, 5% duty cycle) we identified. The LIPUS therapy was performed for one session in the roll-in trial, and 6 sessions in the RCT trial with 3-month intervals for 1.5 years. The primary endpoint was ADAS-J cog scores. The RCT trial was terminated prematurely due to the COVID-19 pandemic. In the roll-in trial (N = 5), no adverse effects were noted. In the RCT trial (N = 22), the worsening of ADAS-J cog scores tended to be suppressed in the LIPUS group compared with the placebo group at week 72 (P = 0.257). When responders were defined as those with no worsening of ADAS-J cog scores at week 72, the prevalence was 50% (5/10) and 0% (0/5) in the LIPUS and placebo groups, respectively (P = 0.053). No adverse effects were noted. These results suggest that the LIPUS therapy is safe and tends to suppress cognitive impairment although a next pivotal trial with a large number of subjects is warranted.