著者

Ying Zhang Wen Hao Jingyao Fan Ruifeng Guo Hui Ai Bin Que Xiao Wang Jianzeng Dong Shaoping Nie

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-23-0164, (Released:2023-08-23)

参考文献数

46

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Background: The effects of obstructive sleep apnea (OSA) on the prognosis of acute coronary syndrome (ACS) without revascularization remain unclear, so the aim of the present study was to elucidate the association of OSA with subsequent cardiovascular events in ACS patients with and without revascularization.Methods and Results: We prospectively recruited hospitalized ACS patients undergoing sleep monitoring between June 2015 and January 2020. OSA was defined as an apnea-hypopnea index ≥15 events/h. The primary endpoint was a major adverse cardiovascular and cerebrovascular event (MACCE), including cardiovascular death, myocardial infarction, stroke, ischemia-driven revascularization, or hospitalization for unstable angina or heart failure. Among 1,927 patients, 52.6% had OSA and 69.4% underwent revascularization. During a 2.9-year follow-up (1.5–3.6 years), the risk of MACCE was similar in patients with or without revascularization. OSA was an independent predictor of MACCE in the non-revascularization group (22.6% vs. 14.6%; hazard ratio (HR) 1.861; 95% confidence interval (CI) 1.239–2.796; P=0.003) but not in revascularization group (22.3% vs. 19.3%; HR 1.135; 95% CI 0.882–1.460; P=0.324). The incremental risk in the non-revascularization group was attributable to more hospitalizations for unstable angina (14.2% vs. 8.6%; HR 1.896; 95% CI 1.124–3.199; P=0.016).Conclusions: For patients with ACS, OSA was independently associated with higher risk of recurrent cardiovascular events among patients without revascularization but not among patients undergoing revascularization. The benefits of suitable OSA treatment for patients without revascularization need further investigation.

著者

Yan Ding Xiaoxin Liang Yuepeng Yan Xiao Wang

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Electronics Express (ISSN:13492543)

巻号頁・発行日

vol.20, no.3, pp.20220526, 2023-02-10 (Released:2023-02-10)

参考文献数

30

被引用文献数

1

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A comprehensive study of air core recta-coax line (ARCL) based on MEMS surface micromachining technology is presented in this paper. The ARCL-to-semi-rectangular coaxial transmission line (SCL) ground-signal-ground (GSG) transition is proposed and designed for probe testing and integration with MMIC chips. To obtain the characteristic impedance of SCL, an equivalent model and theoretical derivation process is presented. In order to consider the effects of processing on performance, electrical effects of dielectric support strap parameters and potential fabrication issues including offset layers and over etching are investigated. For verification, the back-to-back GSG transition is fabricated and measured which has a low insertion loss of 0.13dB up to 50GHz, and a return loss better than -23dB within 5-50GHz. As an example, a demonstration of ARCL with GSG transition for MMIC chips integration is demonstrated.