著者
Yusuke Kondo Shoma Okada Susumu Ohtsuka Takeshi Hirabayashi Aya Adachi Makoto Urata Sho Toshino Hiroshi Miyake Nanako O. Ogawa Naohiko Ohkouchi
出版者
The Plankton Society of Japan, The Japanese Association of Benthology
雑誌
Plankton and Benthos Research (ISSN:18808247)
巻号頁・発行日
vol.13, no.2, pp.66-74, 2018-05-30 (Released:2018-05-24)
参考文献数
50
被引用文献数
1 1

In this study, we investigated the trophic interactions between the Japanese giant box jellyfish, Morbakka virulenta, and fish in the central part of the Seto Inland Sea, western Japan, in autumn and winter. Occurring in the surface waters at nighttime, these cubomedusae, regardless of their size (1.5 to 22.5 cm in bell height), were found to be piscivorous, feeding mainly on the Japanese anchovy, as shown by their stomach contents analysis. This finding was supported by a stable isotopic analysis and by an unchanged cnidome, irrespective of the bell height of medusae. Their nocturnal occurrence near the surface often took place around the slack tide, during which the medusae were foraging with tentacles fully extended. Other associations between the medusae and fish were also observed at this time: presumed commensalism with juvenile Japanese horse mackerel, and predation by black scraper.
著者
Junji Morita Yusuke Kondo Takuya Okada Takayuki Kitai Yuhei Kasai Tsutomu Fujita
出版者
International Heart Journal Association
雑誌
International Heart Journal (ISSN:13492365)
巻号頁・発行日
vol.64, no.4, pp.602-605, 2023-07-29 (Released:2023-07-29)
参考文献数
12
被引用文献数
1

The predictors of pacing capture threshold (PCT) exacerbation after leadless pacemaker implantation remain unknown. We analyzed the predictors of poor PCT by identifying risk factors using multivariate logistic regression analysis for 211 patients with leadless pacemaker implantation. Twenty patients met the criteria for elevated PCT levels and were categorized in the poor PCT group. Multivariate analyses revealed that PCT (P < 0.0001) and pacing impedance (P = 0.03) were independent predictors of PCT exacerbation. Elevated PCT levels and low pacing impedance during leadless pacemaker implantation were potential risk factors for the replacement of leadless pacemakers after the procedure.
著者
Yusuke Kondo Takashi Noda Yukiko Takanashi Shingo Sasaki Yasunori Sato Takashi Nitta Yoshifusa Aizwa Tohru Ohe Takashi Kurita
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-23-0613, (Released:2023-12-07)
参考文献数
30
被引用文献数
1

Background: In 2016, the DANISH study reported negative results regarding the efficacy of implantable cardioverter-defibrillators (ICDs) in patients with non-ischemic cardiomyopathy (NICM) and reduced left ventricular ejection fraction (LVEF). In this study we determined the efficacy of using ICDs for primary prophylaxis in patients with NICM.Methods and Results: We selected 1,274 patients with underlying cardiac disease who were enrolled in the Nippon Storm Study. We analyzed the data of 451 patients with LVEF ≤35% due to NICM or ischemic cardiomyopathy (ICM) who underwent ICD implantation for primary prophylaxis (men, 78%; age, 65±12 years; LVEF, 25±6.4%; cardiac resynchronization therapy, 73%; ICM, 33%). After propensity score matching, we compared the baseline covariates between groups: NICM (132 patients) and ICM (132 patients). The 2-year appropriate ICD therapy risks were 27.7% and 12.2% in the NICM and ICM groups, respectively (hazard ratio, 0.390 [95% confidence interval, 0.218–0.701]; P=0.002).Conclusions: This subanalysis of propensity score-matched patients from the Nippon Storm Study revealed that the risk of appropriate ICD therapy was significantly higher in patients with NICM than in those with ICM.
著者
Satoko Ryuzaki Yusuke Kondo Miyo Nakano Masahiro Nakano Takatsugu Kajiyama Ryo Ito Mari Kitagawa Masafumi Sugawara Toshinori Chiba Yutaka Yoshino Yoshio Kobayashi
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-22-0687, (Released:2023-06-20)
参考文献数
27
被引用文献数
2

Background: Antithrombotic therapy after left atrial appendage closure (LAAC) in patients at high risk of bleeding remains controversial. We present real-world clinical outcomes of LAAC.Methods and Results: Data from 74 consecutive patients who received LAAC therapy between January 2020 and June 2022 were analyzed. Patients received 1 of 3 antithrombotic therapies according to the bleeding risk category or clinical event. Regimen 1 was based on a prior study, regimen 2 comprised a lower antiplatelet drug dose without dual antiplatelet therapy, and regimen 3 was antiplatelet drug administration for as long as possible to patients with uncontrollable bleeding who were required to stop anticoagulant drugs. Overall, 73 (98.6%) procedures were successful. Of them, 16 (21.9%) patients were selected for regimen 1, 46 (63.0%) for regimen 2, and 11 (15.1%) for regimen 3. Device-related thrombosis (13% vs. 0% vs. 0%, P=0.0257) only occurred with regimen 1. There was no difference in major bleeding event rates (6% vs. 2% vs. 9%, P=0.53).Conclusions: The post-LAAC antithrombotic regimen was modified without major concerns.
著者
Yoshiharu SHIMOMURA Yasuyuki KITAURA Yoshihiro KADOTA Takuya ISHIKAWA Yusuke KONDO Minjun XU Miki OTA Yukako MORISHITA Jussiaea V. BARIUAN Hongmin ZHEN
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.61, no.Supplement, pp.S112-S114, 2015 (Released:2015-11-24)
参考文献数
16
被引用文献数
13 18

Branched-chain amino acids (BCAAs) are essential amino acids for humans and are major building blocks of proteins. Recent studies indicate that BCAAs act not only as components of proteins, but also as nutrasignals. In this review, we summarize the findings of recent studies investigating the physiological functions of BCAAs in the regulation of protein and glucose metabolism and brain function.
著者
Yusuke Kondo Tomoka Ogawa Emiri Kanno Masafumi Hirono Takako Kato-Minoura Ritsu Kamiya Toshiki Yagi
出版者
Japan Society for Cell Biology
雑誌
Cell Structure and Function (ISSN:03867196)
巻号頁・発行日
vol.48, no.2, pp.175-185, 2023 (Released:2023-09-23)
参考文献数
54

Ciliary outer-arm dynein (OAD) consists of heavy chains (HCs), intermediate chains (ICs), and light chains (LCs), of which HCs are the motor proteins that produce force. Studies using the green alga Chlamydomonas have revealed that ICs and LCs form a complex (IC/LC tower) at the base of the OAD tail and play a crucial role in anchoring OAD to specific sites on the microtubule. In this study, we isolated a novel slow-swimming Chlamydomonas mutant deficient in the IC2 protein. This mutation, E279K, is in the third of the seven WD repeat domains. No apparent abnormality was observed in electron microscope observations of axonemes or in SDS-PAGE analyses of dynein subunits. To explore the reason for the lowered motility in this mutant, in vitro microtubule sliding experiments were performed, which revealed that the motor activity of the mutant OAD was lowered. In particular, a large difference was observed between wild type (WT) and the mutant in the microtubule sliding velocity in microtubule bundles formed with the addition of OAD: ~35.3 μm/sec (WT) and ~4.3 μm/sec (mutant). From this and other results, we propose that IC2 in an OAD interacts with the β HC of the adjacent OAD, and that an OAD-OAD interaction is important for efficient beating of cilia and flagella.Key words: cilia, axoneme, dynein heavy chain, cooperativity
著者
Akiyo HIRAI Yusuke KONDO Ryoko FUJITA
出版者
The Japan Association for Language Education and Technology
雑誌
外国語教育メディア学会機関誌 (ISSN:21857792)
巻号頁・発行日
vol.58, pp.17-41, 2021 (Released:2021-08-18)

This study examines the accuracy of an automated speech scoring system. The system graded English language learners’ retelling performances according to five features, and its scores were compared to those given by both non-native and native English-speaking (NNES and NES) raters. The results show that, of the five features, words per second was the most consistent predictor of both NNES and NES evaluations. However, the NNES rater tended to pay more attention to exact word similarities between the speech utterances and the original text, while the NES raters focused more on similarities of meaning and gave credit to rephrased expressions. Additionally, the correspondence between the automated scores and those given by human raters was moderate (exact agreement = 48% to 65%; rs = .48 to .52), though less than that between the NNES and NES scores (rs = .70). These results indicate that the automated scoring system for retelling performances may be applicable to low-stakes tests if the speech transcription of learners’ utterances is obtained.
著者
Keitaro Senoo Yusuke Kondo Yoshio Kobayashi Gregory YH Lip
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-17-1164, (Released:2017-12-27)
参考文献数
45
被引用文献数
5

Background:Atrial fibrillation (AF) is the most common arrhythmia in the ageing population in East Asia. Silent cerebral infarction (SCI) is defined as cerebral infarction in the absence of corresponding clinical symptoms, and is a highly prevalent and morbid condition in AF. SCI is increasingly being recognized as a risk factor for future stroke, which can lead to cognitive decline or dementia. The latter is an increasingly common health problem in East Asia.Methods and Results:We conducted a meta-analysis to compare the association of AF and SCI between East Asian and non-Asian patients. AF was associated with SCI in patients with no symptomatic stroke history (relative risk [RR], 2.24; 95% CI: 1.26–3.99, I2=83%; P=0.006) although the prevalence varied widely between studies (P for heterogeneity<0.001). In non-Asian patients, the prevalence of SCI in AF is higher than that in controls (RR, 1.85; 95% CI: 1.65–2.08, I2=17%; P<0.001). There was no significant racial difference between Asian and non-Asian studies (P=0.53).Conclusions:In East Asia, AF was significantly associated with SCI and no racial difference was seen between East Asian and non-Asian patients. The present findings offer clinicians new insights into the association between AF and SCI.