著者
谷崎潤一郎 作
出版者
春陽堂
巻号頁・発行日
1919
著者
髙畑 克徳 髙嶋 博
出版者
日本神経治療学会
雑誌
神経治療学 (ISSN:09168443)
巻号頁・発行日
vol.33, no.1, pp.9-18, 2016 (Released:2016-05-20)
参考文献数
19

Autoimmune encephalopathies are clinically and immunologically heterogeneous disorders. Over time, many different types of autoimmune encephalopathy have been discovered. In such clinical situations, we often recognize that patients with autoimmune encephalopathy are often misdiagnosed as exhibiting functional psychogenic movement, conversion, or somatoform disorders. We clinically analyzed 63 patients (14 males and 49 females; age range, 15–79 years) diagnosed with autoimmune encephalopathy in our hospital from 2013 to 2015. Throughout this period we diagnosed almost no conversion disorders in our department. These patients were diagnosed using the diagnostic criteria for each disease, following clinical features showing neurological symptoms of brain origin, responsiveness to immunosuppressive therapy, the existence of known pathological antibodies, and/or history of human papilloma virus (HPV) vaccination. Fourty–two patients showed motor disturbance (weakness, paresis of extremities, or slower pinching) and 35/42 (83.3%) patients showed give–way weakness, indicating disruption of continuous muscle contraction. Fourty–four patients showed sensory abnormalities such as strong pain, deep muscle pain, dysesthesia, paresthesia, or fast neurologic pain. Surprisingly, most pain was distributed in manner that was not explainable anatomically, while some patients also showed patchy, stocking–glove, or localized pain. Seventeen patients exhibited involuntary movements such as tremor entrainment, dystonia, or coarse involuntary movement. In most patients, such motor, sensory, or involuntary movements were markedly improved with immunosuppressive therapies such as prednisolone, azathioprine, or immune adsorption therapy. We observed memory loss, PNES (psychogenic non–epileptic seizure), dissociative amnesia, hyperventilation, opsoclonus, epilepsy, or autonomic symptoms amongst our patients. Although give–way weakness, anatomically unexplainable pain/abnormal sensation, and strange involuntary movements were thought to be psychogenic, the presence of one of these three symptoms was indicative of autoimmune encephalopathy. As autoimmune encephalitis exhibits diffuse involvement with the whole brain, these symptoms were entirely understandable. Except for the presence of organic disease, most patients were classified into somatoform disorders (DSM–IV, ICD–10) or functional movement disorders. Without first excluding autoimmune encephalopathy, we propose that physicians should not diagnose somatoform disorders. Since autoimmune encephalopathy patients often possess so–called psychogenic signs, it is possible that such signs might be generated by autoimmune encephalopathy instead of somatoform disorders. In conclusion, we propose that give–way weakness and anatomically unexplainable pain/abnormal sensation are key symptoms of autoimmune encephalopathy. We hope that many patients with autoimmune encephalopathy will now be identifiable using our new neurological examination and that each patient can be given an exact diagnosis and therefore be administered with the appropriate treatments.

16 0 0 0 OA 辞林

著者
金沢庄三郎 編
出版者
三省堂
巻号頁・発行日
1911

25 0 0 0 OA 辞林

著者
金沢庄三郎 編
出版者
三省堂
巻号頁・発行日
1907
著者
新村出 校
出版者
開成館
巻号頁・発行日
1911
著者
新井無二郎 著
出版者
大成書院
巻号頁・発行日
1936
著者
ロッシャデソウザ ルシオマヌエル
出版者
東京外国語大学
雑誌
研究活動スタート支援
巻号頁・発行日
2014-08-29 (Released:2014-09-09)

本研究では、ポルトガル、メキシコなどに残る異端審問記録の分析を主におこなった。とりわけ、16世紀後半に日本に滞在したポルトガルのユダヤ系商人であるペレスという一家に関する記録を中心に分析し、そこから当時の長崎におけるコンベルソ商人のコミュニティの存在や、日本人を含む奴隷の生活などが明らかとなった。その成果を英語の単著で公刊した。さらに、ポルトガル人のアジア(とくに日本)における奴隷貿易について、複数の論文を刊行した。そこでは、16~17世紀の南欧語史料の分析をおこない、世界各地でおこなわれた日本人奴隷の取引に関する記録を紹介した。これらの研究の一部は日本語で出版される。
著者
齋藤 真由 白岩 祐子 唐沢 かおり
出版者
日本グループ・ダイナミックス学会
雑誌
実験社会心理学研究 (ISSN:03877973)
巻号頁・発行日
(Released:2018-01-13)
参考文献数
38

本研究の目的は,市民の司法参加に対する認知構造を,広瀬(1994)の要因関連モデルなどで提出されている3つの評価の枠組みから把握するとともに,それらが参加意欲に与える影響を明らかにすることである。本研究が着目した3つの評価とは,市民における知識や経験の有無に関する「実行可能性評価」,負担感についての「コスト評価」,市民による司法参加の効用についての「ベネフィット評価」である。都内の大学生74名を対象とする予備調査で得られた自由回答をもとに,司法参加に対するさまざまな認知を収集し,上記3つの評価に分類した。本調査は都内の大学生を中心とする206名を対象に実施した。因子分析の結果,実行可能性評価とベネフィット評価に関する因子はそれぞれ4つ,コスト評価に関する因子は1つが得られた。その中でもベネフィット評価に含まれる「親和性の向上」と「透明性の向上」が参加意欲を高め,実行可能性評価に関する「知識・経験の欠如」とコスト評価に関する「責任の重さ」が参加意欲を低下させていることが明らかになった。これらの結果にもとづき,今後研究が進むべき方向性について議論した。
著者
田坂 祐一 田中 亮裕 井門 敬子 田中 守 荒木 博陽
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.40, no.4, pp.208-214, 2014-04-10 (Released:2015-04-10)
参考文献数
7
被引用文献数
4 or 0

Pharmacists have increased the provision of pharmaceutical care services to patients. However, the financial benefit of various pharmaceutical interventions has not been well described. In this study, we estimated the original economic impact associated with pharmaceutical interventions by an evidenced-based approach.We classified pharmaceutical interventions into 12 items, which included preventions of serious adverse drug reactions (ADRs), and avoidance of drug interaction. The cost saving associated with preventions of serious ADRs was calculated as ¥2,140,000 per case based on the amount of costs that were paid by the Pharmaceuticals and Medical Devices Agency. Interventions to transvenous antimicrobial therapy were estimated to have a cost saving of ¥190,000 per case based on the literature in Japan. The rates of preventing serious ADRs related to chemotherapy orders, high-risk drugs and others were 5.21%, 3.91% and 2.6%, respectively, based on the literature in the United States. Using this rate, the values of intervention related to chemotherapy orders, high-risk drugs and others were ¥112,000, ¥84,000 and ¥56,000, respectively.The number of interventions was 209 per year, including 3 avoidances of serious ADRs. According to the number of interventions, we calculated that the total cost saving associated with pharmaceutical interventions was ¥22,816,000.This is the first study to estimate the economic impact associated with various pharmaceutical interventions of pharmacists in Japan. Evaluating the economic impact in relation to the pharmaceutical interventions is an important method for assessing the role of pharmacists.
著者
Ian G. Gleadall
出版者
The Japanese Society of Systematic Zoology
雑誌
Species Diversity (ISSN:13421670)
巻号頁・発行日
vol.21, no.1, pp.31-42, 2016-05-25 (Released:2017-02-01)
参考文献数
44
被引用文献数
3 or 0

The East Asian common octopus has long been synonymized with the Atlantic and Mediterranean species Octopus vulgaris Cuvier, 1797. However, evidence from molecular genetic studies has firmly established that the so-called cosmopolitan common octopus is in fact a group of several biogeographically distinct populations which form a complex of species with closely similar morphology. Here, a diagnosis and brief description are provided which distinguish the East Asian common octopus from O. vulgaris, and as a suitable name for it a former junior synonym of O. vulgaris is identified as a valid species: Octopus sinensis d'Orbigny, 1841. A neotype is designated. Voucher material includes specimens collected in Japan by Philipp Franz von Siebold and deposited in the National Museum of Natural History - Naturalis - in Leiden; and others that were studied by Madoka Sasaki in preparation for the detailed description of this species (as O. vulgaris) in a monograph on Japanese Cephalopoda published in 1929. At present, all species in this complex (particularly O. vulgaris and the East Asian species here identified as O. sinensis) are highly vulnerable to overfishing, so recognizing O. sinensis as a species distinct from O. vulgaris is an important step towards improving sustainable fisheries management policies for each species in this group of commercially valuable octopuses.
著者
小滝 富雄
出版者
一般社団法人 日本時計学会
雑誌
日本時計学会誌 (ISSN:00290416)
巻号頁・発行日
vol.40, pp.45-61, 1966-12-01 (Released:2017-11-09)

A theoretical method to obtain the vibration mode of the tuning fork is explained and some discussions are done relating to the obtained vibration mode. Here, the tuning fork is regarded as the one composed of three straight bars which are connected with each other at right angle to form the U-shape. Through the above method, the resonant frequencies n_j (j=1, 2, 3, .....) and the corresponding modes of vibration can be calculated. In the results, it is seen that, when j is odd, the bending motion of the two paralledl sides of the tuning fork are in the opposite direction, when j is even, however, those are in the same direction. Moreover, when two tuning forks are of the similar shape, it is certified that there exists a simple relationship between the vibration modes of these two tuning forks. By using this relationship, unknown vibration modes of the one can be obtained easily, if the modes of the other are known. In the tuning fork, having uniform material and section, the resonant frequencies are given by n_j(k)=m^2_j(k)^-2√<EI/Sp,> where E, p , I, S and l are Young's modulus, the density of the material, the moment of inertia, the area of the section, and the total length of the tuning fork, respectively. k means the ratio of the bottom side length of the U-shape to the parallel side length, and the proportional constants m^2, are shown in a table, with the various values of k. On the asymmetrical tuning forks of which two parallel sides have a slight difference in length, the vibration modes are calculated. The changes of the resonant frequeny and the nodal point are shown in connection with the change of the difference of the parallel sides. The results of the above theoretical analysis are compared with the experimental one, and it is ascertained that both are in good coincidence.
著者
Akio Tanikawa
出版者
Arachnological Society of Japan
雑誌
Acta Arachnologica (ISSN:00015202)
巻号頁・発行日
vol.66, no.1, pp.1-4, 2017-08-31 (Released:2017-09-11)
参考文献数
5

A new araneid species Zygiella hiramatsui n. sp. is described using specimens obtained from Amami-ôshima Island, Japan. This species can be distinguished from allied Z. dispar by the much wider median area of the epigyne, or an unnamed apophysis neighboring the embolus that is short and truncated and a horn shaped apophysis of the tegulum in the male palp. It is uncommon for Zygiella spiders to inhabit subtropical regions, but this is the case for Z. hiramatsui n. sp. So it might be introduced previously into Amami-ôshima Is. from unknown habitat.

4 0 0 0 OA 作詩便覧

著者
塩谷温 著
出版者
弘道館
巻号頁・発行日
1940

31 0 0 0 OA 側頭骨の外傷

著者
小池 正人
出版者
耳鼻咽喉科展望会
雑誌
耳鼻咽喉科展望 (ISSN:03869687)
巻号頁・発行日
vol.43, no.6, pp.570-572, 2000-12-15 (Released:2011-03-18)
参考文献数
5