著者

Toyama Takuji Hoshizaki Hiroshi Isobe Naoki Adachi Hitoshi Naito Shigeto Oshima Shigeru Taniguchi Koichi

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.64, no.12, pp.937-942, 2000-11-20

被引用文献数

6 6

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To identify and quantify the amount of viable hibernating myocardium in patients with chronic coronary artery disease, resting ^<201>Tl single photon emission computed tomography(SPECT) was compared with ^<99m>Tc-methoxy-isobutyl isonitrile(MIBI) SPECT after nitrate infusion (nitrate-^<99m>Tc-MIBI) and ^<201>Tl SPECT after ^<201>Tl with glucose-insulin-potassium infusion (^<201>Tl-GIK) in 25 patients. Twenty-one patients also underwent completely left ventriculography beforehand and 5±4 months afterwards. SPECT images were divided into 9 segments and scored visually from 0 (normal uptake) to 3 (absent). The defect score was calculated as the summation of the total scores(TDS) in each patient. The TDS of nitrate-^<99m>Tc-MIBI images (6.3±4.3) and ^<201>Tl-GIK images (5.8±4.2) were significantly lower than the 7.4±4.3 of resting ^<201>Tl images (p<0.01). Based on the improvement of wall motion after coronary revascularization, the sensitivity of ^<201>Tl-GIK imaging (85%) was significantly higher (p<0.05), and that of nitrate-^<99m>Tc-MIBI imaging (79%) also tended to be higher (p=0.08), than that of ^<201>Tl imaging (62%) in detecting viable myocardium. The specificity of the 3 methods was almost the same. The nitrate-^<99m>Tc-MIBI and ^<201>Tl-GIK methods were more useful than the resting ^<201>Tl method for evaluating viable hibernating myocardium. Furthermore, the ^<201>Tl-GIK method may provide a more accurate estimate of the amount of viable myocardium than the nitrate-^<99m>Tc-MIBI method.

著者

御幡 千里 中川 泰洋 古出 隆士 大柳 光正 河崎 久美 津田 義三 石田 純一郎 小西池 篤 小正 尚裕 安藤 博信 岩崎 忠昭

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.46, 1982-11-01

著者

三谷 頼永 大柳 光正 毛笠 隆夫 山本 茂宏 石田 純一郎 寺脇 一江 羽崎 理恵子 河合 喜孝 岩崎 忠昭

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.48, 1985-04-10

著者

星 光 殿岡 一郎 佐藤 聡 金谷 透 山口 佳子 目黒 光彦 立木 楷 安井 昭二 駒谷 昭夫

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.51, 1988-02-10

著者

飴谷 由佳 清川 裕明 中林 智之 井内 和幸 石川 忠夫 本道 洋昭 西谷 泰 藤村 光夫 神田 享勉

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.59, 1996-02-20

著者

北村 和正 村上 渉 木村 登

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.25, no.10, 1961-10-15

著者

Aoyagi Shigeaki Akashi Hidetoshi Kawara Takemi Ishihara Kenji Tanaka Atsuhisa Kanaya Seiji Koga Yoshinori Ishikawa Ritsuko

出版者

社団法人日本循環器学会

雑誌

Japanese circulation journal (ISSN:00471828)

巻号頁・発行日

vol.62, no.1, pp.64-68, 1997-12-20

被引用文献数

2

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A 26-year-old man was admitted for treatment of congestive heart failure resulting from aortic regurgitation. The patient had been on medical treatment for ulcerative colitis(UC)since he was 14 years old and for ankylosing spondylitis(AS)since he was 20 years old. On admission, gradients of blood pressure among the extremities were observed. Echocardiography revealed marked dilation of the left ventricle(LV), hypokinetic wall motion of the LV, slightly prolapsed aortic cusps with annular dilatation, and severe aortic regurgitation. Camputed tomographic scans demonstrated an aneurysmal dilation of the ascending aorta and thickening of the descending and abdominal aortic wall. Digital subtraction angiography demonstrated an aneurysmal dilation of the ascending aorta;however, there was no clear evidence of steno-occlusive lesions in the brachiocephalic vessels. Blood studies showed positive inflammatory signs and negative rheumatoid factor. HLA typing showed A2, 24(9), B27, 67, Cw1, 7, and DR1, 2. Based on these data, the diagnosis of Takayasu arteritis associated with UC and AS was made. Aortic root replacement was performed. Steroid therapy was restarted immediately after surgery. Histologic studies of the aortic wall showed findings compatible with Takayasu arteritis. The combination of these rare diseases suggests that they have a common pathophysiologic background.