著者
酒本 勝之
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.8, no.8, pp.49-56, 1994-08-10 (Released:2011-09-21)
参考文献数
19
被引用文献数
2
著者
サンシェズ エリー 山川 烈
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.3, no.11, pp.23-33, 1989-11-10 (Released:2011-09-21)
参考文献数
14

この解説は, 医療診断問題におけるファジィ集合論を読者に紹介することを目的とする. 患者の診断にグレードをつけるような, きわどい問題を処理する一般的な方法論を, 具体的な例を用いて説明する. ここで使用する医学的知識は, 言葉で記述された表である. 検査結果の属性と診断の間の関係は, 数値で表されるものではなく, 可能性分布とみなすことのできるファジィ集合 (もっと厳密に言えば, ファジィ・インターバル) のラベルで表現される. ここでは, 可能性測度をどのように用いるか, また検査データから診断を導くのにその可能性測度をどのように組み合わせるかについて述べる.
著者
清水 秀明 松本 元
出版者
一般社団法人 日本生体医工学会
雑誌
医用電子と生体工学 (ISSN:00213292)
巻号頁・発行日
vol.13, no.4, pp.207-213, 1975-08-30 (Released:2011-03-09)
参考文献数
12

The light scattering technique with a photoelectron counting method is applied to determine the average swimming velocities or the velocity distribution of spermatozoa. The results are in quantitative agreement with the ones which are obtained in other methods. This technique has proved useful in 'finding the accurate motility of spermatozoa in a very short observation time.

2 0 0 0 OA 摂食調節と脳

著者
粟生 修司
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.14, no.11, pp.21-28, 2000-11-10 (Released:2011-09-21)
参考文献数
18
著者
浜田 良機 天野 力郎
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.4, no.5, pp.33-39, 1990-05-10 (Released:2011-09-21)
参考文献数
19

2 0 0 0 OA 免疫機能と脳

著者
片渕 俊彦
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.14, no.11, pp.65-72, 2000-11-10 (Released:2011-09-21)
参考文献数
26
著者
坪子 侑佑 渡辺 祥太 白石 泰之 三浦 英和 山田 昭博 鈴木 拓志 平 恭紀 山家 智之
出版者
一般社団法人 日本生体医工学会
雑誌
生体医工学
巻号頁・発行日
vol.53, pp.S200_01-S200_01, 2015

The authors have been developing a pulmonary mechanical simulator in order to establish a design parameters of a novel artificial cardiovascular devices. In pulmonary circulation, interactive pressure-flow changes are regulated by pulmonary impedance characteristics. We focused on the native impedance characteristics variation in the pulmonary circulation. To examine the effect of respiratory control on pulmonary resistance, we measured pulmonary arterial pressure and flow in adult goat under the different respiratory settings with open/closed-chest condition. Pulmonary input impedance in two respiratory conditions under the anesthetized open-chest positive pressure ventilation (PPV) and the awake spontaneous respiration (SR) were calculated. Longitudinal impedance at 0 Hz in SR showed lower than in PPV, and at high harmonic area in SR was bigger than in PPV. In order to examine the hemodynamic response for newly designed artificial internal organs, pulmonary impedance variation caused by respiratory control should be considered. For sophisticated pulmonary resistance model, reproducing the negative pressure condition in the thoracic cavity, and pulmonic vascular resistance regulation might be required.
著者
稲永 和豊
出版者
一般社団法人 日本生体医工学会
雑誌
BME (ISSN:09137556)
巻号頁・発行日
vol.1, no.5, pp.379-382, 1987-05-10 (Released:2011-09-21)
参考文献数
8

脳の機能的診断には, 直接に脳から発生している脳波, 誘発電位を調べる方法があるが, 間接的に脳機能を調べる方法として眼球運動, 光眼輪筋反射, マイクロバイブレーシヨンなども役に立つ方法である.
著者
田中 邦雄 佐野 文男 阿部 善右衛門
出版者
一般社団法人 日本生体医工学会
雑誌
医用電子と生体工学 (ISSN:00213292)
巻号頁・発行日
vol.12, no.2, pp.81-89, 1974-04-30 (Released:2011-03-09)
参考文献数
25
被引用文献数
1

Several papers on the applications of the nuclear magnetic resonance (NMR) technique-for the biological measurements have been published since the first proposal of the NMR blood flowmeter by Bowman. However, the problems arising inherently from the non-invasive measurements of the specified area in the body were not discussed in these papers. The authors proposed previously the magnetic focusing technique as one of the new approaches and discussed some problems related to this technique.In this paper, some basic problems of the applications of NMR for the non-invasive measurements are discussed and the fundamental properties affecting the measuring sensitivity attained by the magnetic focusing technique is analyzed. The problems treated and the obtained results are as follows : 1) The relations among parameters such as relaxation times and radio frequency magnetic field which influence the measuring sensitivity are experimentally analyzed.2) The distributions of RF magnetic field inside or outside the transmitter coil are theoretically calculated. Approximate values of relaxation time of 1-2 sec. and 0.1-1 sec. are experimentally obtained respectively with the various body fluids and tissues of the dog and the human. Philosophy of choosing the appropriate parameters are discussed based on these results by taking the saturation factor in Bloch's equation and the measuring sensitivity into account.3) Application for the tumor detection is discussed and the differences of 20% and 200% in relaxation time between normal and cancer cases are experimentally obtained respectively with the tissues from the stomach and the breast. Further, it has been found that the relation between hematocrit of blood and its relaxation time was linear.4) The deterioration of signal output by body tissues is examined by a model experiment. According to this experiment, it is shown that the deterioration of S/N ratio was equal to approximately 30%, at f = 60 MHz.5) From above results, in the case of applying our proposed magnetic focusing technique, the resolution or the minimally detectable volume of water in the typical organs by S/N of unity at resonance frequency of 60 MHz should be about 0.3 ml.
著者
萩 浩司 牧川 方昭 飯泉 仁美
出版者
一般社団法人 日本生体医工学会
雑誌
医用電子と生体工学 (ISSN:00213292)
巻号頁・発行日
vol.33, no.4, pp.334-342, 1995 (Released:2011-10-14)
参考文献数
19

In this study we have developed a transcutaneous digital communication technique by using Pulse-Code-Modulated (PCM) infrared rays. The communication protocol examined here is serial, asynchronous and half duplex. The electric power should be considered for a computer system implanted inside the body, because it is driven by batteries and the power is insufficient. Its size should also be miniaturized as small as possible. Therefore the following methods were adopted here; the weak infrared rays emitted inside the body were received by a high sensitive avalanche photodiode; the infrared rays of high brightness was used to send data into inside of the body; and the digital data were converted into an optical signal after the pulse-code-modulation (PCM). This modulation yields some advantages; 1) absorbing the response delay of the photosensor, 2) intensifying infrared rays luminescence outside body and 3) saving the electric power on the luminescence inside body. Some communication experiments were done by using pork with the skin; the communication speed was 9600 baud from inside to outside and 1200 baud in the opposite direction, 15 infrared LEDs were set for outside of the body, 4 for inside, three nickel hydride batteries of 1200mAh were used for an electric power inside the body. As a result, a stable bi-directional digital communication was realized through the skin and the pork of about 9cm and it could continue to operate for about 19 hours.
著者
石山 陽事 白井 康之 野沢 胤美 関 要次郎 本間 伊佐子 江部 充
出版者
一般社団法人 日本生体医工学会
雑誌
医用電子と生体工学 (ISSN:00213292)
巻号頁・発行日
vol.28, no.2, pp.113-121, 1990 (Released:2011-10-14)
参考文献数
12

This study presented the available effects of Source Derivation (SD) method for detecting the focal EEG, from the model experiments which were compared the traditional monopolar derivation with SD method, and also from the clinical recording for the patients, Signal dipole and EEG noise dipole embeded in a spherical volume conducted covered with three layer shells corresponding to neural tissue, skull and scalp, were used for the model. The following conclusions were obtained. 1) It was proved by the model experiment that SD method was useful for the detection of focal signal dipole potential on cortical surface. 2) SD method was useful to detect the signal not only in the cortical surface but also in the deep cortical area, when the reference electrode angle of SD method was smaller to the active electrode (α=10°-20°), that is, the distance of electrodes on scalp surface was about 1.6-3.2cm. 3) SD method was applied to the patients with focal spikes. The localization of the focal spike was more clear than the traditional ear reference monopolar recording. S/N to back ground EEG also was improved very well. 4) Identification of the location generated of primary responses in somatosensory evoked potential (SEP) by electrical stimulation of median nerve was tried by using the SD method with intererectrode distance of 2cm, and consequently the central sulcus and cortical primary sensory area were identified from the phase-reversal of SEP on the scalp.