著者

今井 理衣 金 佑香 岡野 周志 近藤 竜太

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.11, no.4, pp.38-42, 2022-12-27 (Released:2022-12-27)

参考文献数

8

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A 9-year-old neutered female British shorthair cat presented with anorexia. Physical examination revealed stomatitis and gingival ulcer of the maxillary anterior acetabulum. Computed tomography showed a bone-infiltrating neoplastic lesion in the maxilla invading the orbit. A core biopsy of the lesion along with imaging studies and laboratory examinations revealed stage 3 oral squamous cell carcinoma. An esophageal fistula tube was placed and administration of analgesics and molecular-targeted drugs was initiated. After a month, palliative irradiation was performed. The cat tolerated without significant side effects during the 197-day administration of the molecular-targeted drug. Later in treatment, radiation therapy caused necrosis of the bone and skin. However, for most part of the 227-day survival, quality of life was well maintained with pain relief and dietary supplements.

著者

遠藤 美紀 重黒木 恵子 大町 哲夫 山田 武喜

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.11, no.4, pp.33-37, 2022-12-27 (Released:2022-12-27)

参考文献数

20

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A 10-year-old 4.7-kg spayed female mix breed dog presented with mucoid vaginal discharge despite treatment for cystitis for a month. A malignant neoplasm was suspected based on atypical cells found on vaginal mucus cytology. A cystoscopy biopsy was performed, and the histopathologic diagnosis was consistent with transitional cell carcinoma (TCC). A subtotal urethrectomy and urethral-vaginal anastomosis were performed. Treatment with piroxicam (0.3mg/kg eod for 1278 days) and carboplatin (150~250mg/m2/3~4 weeks, nine times) was initiated 2 weeks postoperatively. Other than recurrent cystitis that started 3 weeks postoperatively, the patient maintained a good quality of life with neither recurrence nor metastasis. The patient died of renal failure 3 years and 9 months (1395 days) after the initial visit. While TCC is generally considered to have poor prognosis, it was suggested from the management of this case that early diagnosis and radical surgery could achieve good long-term survival.

著者

杉山 大樹 圓尾 拓也 信田 卓男 石川 剛司 金久保 佳代 斑目 広郎 茅沼 秀樹 菅沼 常徳

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.1, no.1, pp.8-13, 2010 (Released:2010-02-26)

参考文献数

16

被引用文献数

1 2

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肺指症候群と考えられた猫5例の臨床所見について検討を行った。肺原発巣に伴う呼吸器徴候は5例中1例のみで見られ、ほかの4例では呼吸器症状は全くみられなかった。播種転移部位は、主に、指、体表部筋肉、皮膚であった。5例の中央生存期間は60日(12~125)であり、呼吸器徴候を伴い死亡したものは1例のみであった。これらの臨床所見から、本病態における治療として、肺葉切除は意義が低いことが示唆された。また、転移病変は全身に存在することから、断指をはじめとする外科的治療は残存する指や肢の負重増加により動物の生活の質をさらに低下させる可能性が示唆された。

著者

伊藤 秀俊 伊藤 詩織 近藤 広孝

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.11, no.2, pp.17-21, 2022-05-30 (Released:2022-05-30)

参考文献数

12

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A 12-year-old castrated male Shih Tzu presented to the hospital with hematuria that had lasted for about 1 month. Abdominal ultrasonography and computed tomography revealed hydronephrosis due to a mass in the left urinary tract and a left adrenal tumor. Adrenal glandectomy and nephroureterectomy were performed. The histopathological examination revealed concurrent adrenocortical adenoma and pheochromocytoma in the same adrenal gland. A fibroepithelial polyp developed in the left ureter, with subsequent hydronephrosis. There was no recurrence or metastasis of adrenocortical adenoma, pheochromocytoma or the ureteral fibroepithelial polyp after surgical removal.

著者

児玉 恵子 児玉 和仁

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.10, no.2, pp.19-24, 2021-12-31 (Released:2021-12-21)

参考文献数

23

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11才、避妊手術済雌のチワワが健康診断のために来院した。超音波検査を実施したところ、脾臓に蜂の巣状エコー所見が認められ、FNAとリンパ球のPARRの結果からB-cellリンパ腫が疑われた。脾臓摘出術が実施され、マントル細胞リンパ腫(MCL)と診断された。第511病日、体表リンパ節が腫大しB-cellリンパ腫と診断された。遺伝子シークエンス解析により、脾臓のMCLとリンパ節のリンパ腫は異なり、それぞれ独立して発生したことが明らかになった。このことから、同じリンパ節の悪性腫瘍にも関わらず、脾臓に限局したMCLは脾摘単独で良好に治療可能であると考えられる。

著者

保坂 創史 小宮 直孝 保坂 記世

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.10, no.1, pp.7-12, 2021-10-31 (Released:2021-10-26)

参考文献数

22

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An old neutered male cat was brought to the hospital with primary signs of anorexia, difficulty breathing, abdominal distension, and purulent rhinorrhea. Clinical examinations showed tension pneumoperitoneum and an intraperitoneal mass of 4 cm in diameter. A needle puncture was performed, releasing 830 mL of gas, at which point breathing improved. A laparotomy was then performed, and a jejunal mass leaking air was excised, followed by abdominal closure. The mass was diagnosed as lymphoma. It is assumed that the lymphoma gave rise to gastrointestinal perforation, which, together with chronic obstructive nasal disease, led to the tension pneumoperitoneum. The pneumoperitoneum did not recur after surgery, and the cat’s condition improved.

著者

水野 累 米丸 加余子 森 崇

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.10, no.1, pp.1-6, 2021-10-31 (Released:2021-10-26)

参考文献数

11

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A 14- year-old spayed female miniature Dachshund presented to our hospital with a mass at a previous incision site 7 months after the removal of a lung adenosquamous cell carcinoma (ASCC). Needle tract implantation (NTI) caused by fine needle biopsy was presumed as the cause of the mass. Extended resection of the mass was performed and histopathological examination revealed ASCC and thyroid transcription factor-1 (TTF-1) positivity. No local recurrence was observed; however, the dog died. The incidence of NTI in lung ASCC in dogs is unknown. However, the development of NTI should be monitored.

著者

水野 累 米丸 加余子 森 崇

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

pp.2020-003, (Released:2021-05-19)

参考文献数

11

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A 14- year-old spayed female miniature Dachshund presented to our hospital with a mass at a previous incision site 7 months after the removal of a lung adenosquamous cell carcinoma (ASCC). Needle tract implantation (NTI) caused by fine needle biopsy was presumed as the cause of the mass. Extended resection of the mass was performed and histopathological examination revealed ASCC and thyroid transcription factor-1 (TTF-1) positivity. No local recurrence was observed; however, the dog died. The incidence of NTI in lung ASCC in dogs is unknown. However, the development of NTI should be monitored.

著者

前川 卓哉 西川 晃司 吉田 進太郎 酒井 健嗣 西川 秀司

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.9, no.1, pp.6-9, 2020-12-31 (Released:2020-12-11)

参考文献数

6

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A 13-year-old intact male Shih-Tzu presented with a 2-month history of gastrointestinal signs. A mechanical ileus developed due to an obstruction from an intramural tumor in the small intestine that was surgically resected. The tumor was diagnosed as a high-grade intestinal T-cell lymphoma with incomplete margins and serosal and mesentery extension. CHOP chemotherapy (vincristine, cyclophosphamide, doxorubicin, and prednisolone) was applied, but during the CHOP protocol, the dog developed a nodule on the skin in the scapular area. Histopathological examination of a punch biopsy revealed a high-grade cutaneous T-cell lymphoma. Lomustine was administered and the cutaneous T-cell lymphoma was surgically resected and histologically diagnosed to have complete margins. However, the dog experienced progressive disease. With adjuvant chemotherapy including dexamethasone, melphalan, actinomycin D, and cytosine arabinoside (DMAC), and chlorambucil, methotrexate, and prednisolone (LMP), the patient lived for 571 days in relatively good health condition. No evidence of recurrence nor metastasis was revealed at necropsy. This case suggests the benefit of surgical resection for both intestinal and cutaneous T-cell lymphoma lesions. However, further studies are required to investigate the effect of chemotherapy, remission rate, survival time, and impact on the quality of life.

著者

五十嵐 宏之 五十嵐 恭子

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.9, no.1, pp.1-5, 2020-12-31 (Released:2020-12-11)

参考文献数

13

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A 10-year-old female mongrel dog presented with abdominal distension. Physical, radiographic, and ultrasound examinations detected an intestinal mass and ascites. Laparotomy revealed that the mass originated from the cecum and disseminated in the omentum and pancreas. Surgical resection of the mass and disseminated lesions was performed. Histopathological examination revealed the mass and lesions to be gastrointestinal stromal tumors (GISTs). Imatinib mesylate (10 mg/kg/sid) was administered for 355 days postoperatively. The dog survived for > 855 days with no recurrence and metastasis. Adjuvant chemotherapy with imatinib mesylate may be an effective treatment for GIST.

著者

水上 浩一 加藤 めぐみ 加藤 秀之

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.8, no.1, pp.8-11, 2019-10-31 (Released:2019-10-31)

参考文献数

8

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Parathyroid adenoma is a relatively rare disease in dogs. However, hypercalcemia caused by excessive secreted parathyroid hormone occurs as a paraneoplastic syndrome, and significantly lowers the patient’s quality of life Therefore, prompt diagnosis and treatment are required in this condition. In this communication, we report two canine parathyroid adenoma cases in Miniature Dachshunds, with one case showing delayed postoperative functional recovery of the parathyroid, and another case having multiple adenoma lesions.

著者

山田 徹

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

pp.2021-001, (Released:2023-10-11)

参考文献数

19

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A 10-year-old spayed female cat presented to our hospital exhibiting symptoms of fatigue and a drooping head. Upon examination, the cat was diagnosed with hypokalemia and an enlarged right adrenal gland. Effective management of the hypokalemia was achieved through medication. However, during the course of follow-up, on day 646, the cat developed diabetes mellitus. Subsequently, on day 899, the cat displayed signs of hypertrophic osteopathy. The hypertrophic osteopathy exhibited a progressive course, and the cat died on follow-up day 1109. Although an autopsy was not conducted, the case was characterized by an adrenal tumor accompanied by multiple hormonal abnormalities.

著者

児玉 和仁 児玉 恵子

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

pp.2021-005, (Released:2023-03-31)

参考文献数

32

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A 4-year-old neutered male Scottish Terrier, weighing 10.4 kg, presented with hematuria for the past 10 days. Ultrasonography revealed multiple masses in the apex and trigone of the bladder. A catheter biopsy was performed, and the histopathological diagnosis was non-invasive urothelial carcinoma (transitional cell carcinoma) with low to medium grade pathological malignancy. Treatments with piroxicam alone, vinblastine and firocoxib, toceranib and firocoxib, and firocoxib alone resulted in a partial response or stable disease. The patient showed no regional lymph node metastasis or distant metastases, maintained stable disease, and had an excellent quality of life at 1681 days after the start of treatment.

著者

信田 卓男 福岡 里江子 圓尾 拓也 伊藤 哲郎 川村 裕子 武田 晴央 杉山 大樹 石川 剛司 山田 徹 斑目 広郎 茅沼 秀樹 菅沼 常徳

出版者

一般社団法人日本獣医がん学会

雑誌

日本獣医がん学会雑誌 (ISSN:18843344)

巻号頁・発行日

vol.1, no.4, pp.58-63, 2010 (Released:2010-12-15)

参考文献数

25

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犬のリンパ腫107例に対して、L-アスパラギナーゼとプレドニゾロンにより初期導入を行い、その反応を分析した。評価可能であった104例のうち、寛解率は92.3%(完全寛解27.9%、部分寛解64.4%)であった。皮膚型リンパ腫より多中心型リンパ腫の方が、有意に寛解率が高かったものの(p=0.045)、ステージ、サブステージ、ステロイド投与歴による差は認められなかった。臨床的に有意なアナフィラキシー反応や膵炎は認められなかった。以上のことから、L-アスパラギナーゼとプレドニゾロンによるダウンステージを目的とした導入は、有効であると考えられた。