文献一覧: NATURE PUBLISHING GROUP (出版者)

1 0 0 0 IR Molecular decoding using luminescence from an entangled porous framework.

著者: Takashima Yohei Martínez Virginia Martínez Furukawa Shuhei Kondo Mio Shimomura Satoru Uehara Hiromitsu Nakahama Masashi Sugimoto Kunihisa Kitagawa Susumu
出版者: Nature Publishing Group
雑誌: Nature communications (ISSN:20411723)
巻号頁・発行日: vol.2, no.1, 2011-01-25
被引用文献数: 712

「ちえのわ」型ナノ細孔を用いたセンサー開発に成功: 動き、捕まえ、光って知らせるナノ多孔体. 京都大学プレスリリース. 2011-01-26.Chemosensors detect a single target molecule from among several molecules, but cannot differentiate targets from one another. In this study, we report a molecular decoding strategy in which a single host domain accommodates a class of molecules and distinguishes between them with a corresponding readout. We synthesized the decoding host by embedding naphthalenediimide into the scaffold of an entangled porous framework that exhibited structural dynamics due to the dislocation of two chemically non-interconnected frameworks. An intense turn-on emission was observed on incorporation of a class of aromatic compounds, and the resulting luminescent colour was dependent on the chemical substituent of the aromatic guest. This unprecedented chemoresponsive, multicolour luminescence originates from an enhanced naphthalenediimide-aromatic guest interaction because of the induced-fit structural transformation of the entangled framework. We demonstrate that the cooperative structural transition in mesoscopic crystal domains results in a nonlinear sensor response to the guest concentration.

2014-08-22 18:45:14
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1 0 0 0 OA Community structure of planktonic methane-oxidizing bacteria in a subtropical reservoir characterized by dominance of phylotype closely related to nitrite reducer

著者: Kojima Hisaya Tokizawa Riho Kogure Kouhei Kobayashi Yuki Itoh Masayuki Shiah Fuh-Kwo Okuda Noboru Fukui Manabu
出版者: Nature Publishing Group
雑誌: Scientific Reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-07-25
被引用文献数: 32

湖水中でのメタン消費の新たな主役 -亜熱帯ダム湖で脱窒メタン酸化細菌が優占していることを発見-. 京都大学プレスリリース. 2014-07-31.

2014-08-08 13:22:23
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1 0 0 0 OA Accelerated discovery of cathode materials with prolonged cycle life for lithium-ion battery.

著者: Nishijima Motoaki Ootani Takuya Kamimura Yuichi Sueki Toshitsugu Esaki Shogo Murai Shunsuke Fujita Koji Tanaka Katsuhisa Ohira Koji Koyama Yukinori Tanaka Isao
出版者: Nature Publishing Group
雑誌: Nature communications (ISSN:20411723)
巻号頁・発行日: vol.5, 2014-08-01
被引用文献数: 106

革新的材料設計手法により超長寿命2次電池開発に成功 -多数の高精度計算データを活用して材料開発を大幅に加速-. 京都大学プレスリリース. 2014-07-30.

2014-08-05 15:43:40
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1 0 0 0 OA Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition

著者: Maharjan Sunita Oku Masahide Tsuda Masashi Hoseki Jun Sakai Yasuyoshi
出版者: Nature Publishing Group
雑誌: Scientific Reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-07-31
被引用文献数: 154

タンパク質分解装置の活性低下が細胞死を引き起こす初期経路の同定と食品成分による回復. 京都大学プレスリリース. 2014-07-31.

2014-08-04 09:34:25
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1 0 0 0 OA Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform.

著者: Yoshimi K Kaneko T Voigt B Mashimo T
出版者: Nature Publishing Group
雑誌: Nature communications (ISSN:20411723)
巻号頁・発行日: vol.5, 2014-06-26
被引用文献数: 152

CRISPR/Casシステムを用いたアレル特異的ゲノム編集とラット毛色突然変異の修復!.京都大学プレスリリース. 2014-06-27.

2014-06-30 13:21:46
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1 0 0 0 OA MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.

著者: Horie Takahiro Nishino Tomohiro Baba Osamu Kuwabara Yasuhide Nakao Tetsushi Nishiga Masataka Usami Shunsuke Izuhara Masayasu Nakazeki Fumiko Ide Yuya Koyama Satoshi Sowa Naoya Yahagi Naoya Shimano Hitoshi Nakamura Tomoyuki Hasegawa Koji Kume Noriaki Yokode Masayuki Kita Toru Kimura Takeshi Ono Koh
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-06-16
被引用文献数: 44

マウスへのマイクロRNA-33bの導入に成功 -ヒトでのHDL-コレステロールの質の改善に期待-. 京都大学プレスリリース. 2014-06-17.

2014-06-19 15:33:30
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1 0 0 0 OA Tug-of-war of microtubule filaments at the boundary of a kinesin- and dynein-patterned surface.

著者: Ikuta Junya Kamisetty Nagendra K Shintaku Hirofumi Kotera Hidetoshi Kon Takahide Yokokawa Ryuji
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014
被引用文献数: 16

「分子綱引き」をおこなうナノシステムを開発 -細胞分裂や細胞内物質輸送の仕組みを知るカギに-.京都大学プレスリリース. 2014-06-17.

2014-06-17 17:41:02
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1 0 0 0 IR Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.

著者: DOI M
出版者: Nature Publishing Group
雑誌: Nature medicine (ISSN:1546170X)
巻号頁・発行日: vol.16, no.1, pp.67-74, 2010-01
被引用文献数: 11 339

生体リズム異常に伴う高血圧発症メカニズムを解明しました. 京都大学プレスリリース. 2009-12-14. http://www.kyoto-u.ac.jp/ja/news_data/h/h1/news6/2009/091214_2.htmMalfunction of the circadian clock has been linked to the pathogenesis of a variety of diseases. We show that mice lacking the core clock components Cryptochrome-1 (Cry1) and Cryptochrome-2 (Cry2) (Cry-null mice) show salt-sensitive hypertension due to abnormally high synthesis of the mineralocorticoid aldosterone by the adrenal gland. An extensive search for the underlying cause led us to identify type VI 3beta-hydroxyl-steroid dehydrogenase (Hsd3b6) as a new hypertension risk factor in mice. Hsd3b6 is expressed exclusively in aldosterone-producing cells and is under transcriptional control of the circadian clock. In Cry-null mice, Hsd3b6 messenger RNA and protein levels are constitutively high, leading to a marked increase in 3beta-hydroxysteroid dehydrogenase-isomerase (3beta-HSD) enzymatic activity and, as a consequence, enhanced aldosterone production. These data place Hsd3b6 in a pivotal position through which circadian clock malfunction is coupled to the development of hypertension. Translation of these findings to humans will require clinical examination of human HSD3B1 gene, which we found to be functionally similar to mouse Hsd3b6.

2014-03-29 02:45:18
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1 0 0 0 OA An evolutionarily conserved protein CHORD regulates scaling of dendritic arbors with body size.

著者: Shimono Kohei Fujishima Kazuto Nomura Takafumi Ohashi Masayoshi Usui Tadao Kengaku Mineko Toyoda Atsushi Uemura Tadashi
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-03-19
被引用文献数: 30

体の大きさに合わせて神経細胞の大きさを制御するしくみを解明. 京都大学プレスリリース. 2014-03-17.

2014-03-26 09:55:44
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1 0 0 0 OA Control of hot-carrier relaxation for realizing ideal quantum-dot intermediate-band solar cells.

著者: Tex David M Kamiya Itaru Kanemitsu Yoshihiko
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-02-18
被引用文献数: 26

量子ナノ構造を利用した太陽電池の光キャリアの振る舞いを解明 -高効率太陽電池の実現に前進-.京都大学プレスリリース.2014-2-18.

2014-02-21 14:47:10
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1 0 0 0 OA Critical roles of nardilysin in the maintenance of body temperature homoeostasis.

著者: Hiraoka Yoshinori Matsuoka Tatsuhiko Ohno Mikiko Nakamura Kazuhiro Saijo Sayaka Matsumura Shigenobu Nishi Kiyoto Sakamoto Jiro Chen Po-Min Inoue Kazuo Fushiki Tohru Kita Toru Kimura Takeshi Nishi Eiichiro
出版者: Nature Publishing Group
雑誌: Nature communications (ISSN:20411723)
巻号頁・発行日: vol.5, 2014-02-04
被引用文献数: 33

「体温恒常性維持のメカニズムの解明」に成功. 京都大学プレスリリース. 2014-02-04.

2014-02-06 10:52:17
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1 0 0 0 OA Spatio-temporal dynamics in collective frog choruses examined by mathematical modeling and field observations.

著者: Aihara Ikkyu Mizumoto Takeshi Otsuka Takuma Awano Hiromitsu Nagira Kohei Okuno Hiroshi G Aihara Kazuyuki
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.4, 2014-01-27
被引用文献数: 53

カエルの合唱の法則を数学と光計測を使って発見. 京都大学プレスリリース. 2014-01-27.

2014-02-04 13:08:44
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1 0 0 0 OA Investigation of the open-circuit voltage in solar cells doped with quantum dots.

著者: Tayagaki Takeshi Hoshi Yusuke Usami Noritaka
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.3, 2013
被引用文献数: 64

量子ドットを用いた結晶シリコン太陽電池の高効率化に向けた設計指針を提供. 京都大学プレスリリース. 2013-09-26.

2013-10-03 15:36:49
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1 0 0 0 OA Conferring the ability to utilize inorganic polyphosphate on ATP-specific NAD kinase

著者: Nakamichi Yusuke Yoshioka Aya Kawai Shigeyuki Murata Kousaku
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.3, 2013-09-11
被引用文献数: 17

ATP特異性の獲得メカニズムの解明 : 新薬と新しい物質生産系の開発に期待. 京都大学プレスリリース. 2013-09-11.

2013-09-27 16:42:43
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1 0 0 0 OA Biological soliton in multicellular movement

著者: Kuwayama Hidekazu Ishida Shuji
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.3, pp.2272, 2013-07
被引用文献数: 49

Solitons have been observed in various physical phenomena. Here, we show that the distinct characteristics of solitons are present in the mass cell movement of non-chemotactic mutants of the cellular slime mould Dictyostelium discoideum. During starvation, D. discoideum forms multicellular structures that differentiate into spore or stalk cells and, eventually, a fruiting body. Non-chemotactic mutant cells do not form multicellular structures; however, they do undergo mass cell movement in the form of a pulsatile soliton-like structure (SLS). We also found that SLS induction is mediated by adhesive cell-cell interactions. These observations provide novel insights into the mechanisms of biological solitons in multicellular movement.

2013-08-28 08:31:29
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1 0 0 0 OA DNA replication-dependent binding of CTCF plays a critical role in adenovirus genome functions

著者: Komatsu Tetsuro Sekiya Takeshi Nagata Kyosuke
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.3, pp.2187, 2013-07
被引用文献数: 14

The expression of adenovirus late genes is shown to require viral DNA replication, but its mechanism remains elusive. Here we found that knockdown of CTCF suppresses viral DNA replication as well as late, but not early, gene expression. Chromatin immunoprecipitation assays indicated that CTCF binds to viral chromatin depending on viral DNA replication. These findings depict CTCF as a critical regulator for adenovirus genome functions in late phases of infection.

2013-08-28 08:31:13
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1 0 0 0 OA Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p–Pex21p

著者: Pan Dongqing Nakatsu Toru Kato Hiroaki
出版者: Nature Publishing Group
雑誌: Nature Structural & Molecular Biology (ISSN:15459993)
巻号頁・発行日: 2013-06-30
被引用文献数: 53 23

ペルオキシソーム病RCDP-1の分子機構の解明.京都大学プレスリリース.2013-07-01.

2013-07-03 11:50:40
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1 0 0 0 OA Inter-brain synchronization during coordination of speech rhythm in human-to-human social interaction

著者: Kawasaki Masahiro Yamada Yohei Ushiku Yosuke Miyauchi Eri Yamaguchi Yoko
出版者: Nature Publishing Group
雑誌: Scientific reports (ISSN:20452322)
巻号頁・発行日: vol.3, pp.1692, 2013-04
被引用文献数: 152 9

Behavioral rhythms synchronize between humans for communication; however, the relationship of brain rhythm synchronization during speech rhythm synchronization between individuals remains unclear. Here, we conducted alternating speech tasks in which two subjects alternately pronounced letters of the alphabet during hyperscanning electroencephalography. Twenty pairs of subjects performed the task before and after each subject individually performed the task with a machine that pronounced letters at almost constant intervals. Speech rhythms were more likely to become synchronized in human–human tasks than human–machine tasks. Moreover, theta/alpha (6–12 Hz) amplitudes synchronized in the same temporal and lateral-parietal regions in each pair. Behavioral and inter-brain synchronizations were enhanced after human–machine tasks. These results indicate that inter-brain synchronizations are tightly linked to speech synchronizations between subjects. Furthermore, theta/alpha inter-brain synchronizations were also found in subjects while they observed human–machine tasks, which suggests that the inter-brain synchronization might reflect empathy for others' speech rhythms.

2013-06-04 08:30:14
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1 0 0 0 OA Xenoturbella bocki exhibits direct development with similarities to Acoelomorpha

著者: Nakano Hiroaki Lundin Kennet Bourlat Sarah J. Telford Maximilian J. Funch Peter Nyengaard Jens R. Obst Matthias Thorndyke Michael C.
出版者: Nature Publishing Group
雑誌: Nature Communications (ISSN:20411723)
巻号頁・発行日: vol.4, pp.1537, 2013-02
被引用文献数: 31 2

Xenoturbella bocki, a marine animal with a simple body plan, has recently been suggested to be sister group to the Acoelomorpha, together forming the new phylum Xenacoelomorpha. The phylogenetic position of the phylum is still under debate, either as an early branching bilaterian or as a sister group to the Ambulacraria (hemichordates and echinoderms) within the deuterostomes. Although development has been described for several species of Acoelomorpha, little is known about the life cycle of Xenoturbella. Here we report the embryonic stages of Xenoturbella, and show that it is a direct developer without a feeding larval stage. This mode of development is similar to that of the acoelomorphs, supporting the newly proposed phylum Xenacoelomorpha and suggesting that the last common ancestor of the phylum might have been a direct developer.