著者

末武 光子 入間田 美保子 高橋 辰 沖津 尚弘 大山 健二

出版者

Japan Otological Society

雑誌

Otology Japan (ISSN:09172025)

巻号頁・発行日

vol.10, no.2, pp.89-94, 2000-05-25 (Released:2011-06-17)

参考文献数

5

被引用文献数

5

---

Mucoud otitis is known to be caused by mucoid typeStreptococcus pneumoniae, and the most of them are serotype 3. As the result of the development of antibiotics this bacteria has once been regarded as an unimportant pathogen. However recently, there are found severe cases in which this pathogen is responsible.During the period from January 1998 to July 1999, we have treated 25 cases in which the mucoid typeStreptococcus pneumoniaewas isolated.Based on these experiences, we summarized the current status of the mucoid otitis media as follows.1. The distribution of patients suffering from mucoid otitis medid ranged infants to elderly people. 2. The patients presented with symptomes, such as severe earache, headache, high fever, profuse otorrhea, aggravation of sensorineural hearing. 3. The relief of the symptomes is usually better and earlier when penicillin was selected as a first choice, while when cephem antibiotics were selected, healing of the otitis media tend to be delayed. 4. As 13 out of 14 strains isolated in 1999 were found to be penicillin-insensitiveStreptococcus pneumoniae (PISP) withpbp2xgene, it is conceivable that the resistance of this pathogen against cephem is under a rapid progress, probably due to abuse cephem in the past in this country. 5. The antibiotics of the first choice against mucoid otitis media is penicillin. If the pathogen would acquire penicillin resistance, treatment of mucoid otitis media may become as difficult as it used be in old days of preantibiotics. We should pay enough attention to this disease as an important reemerging infectious disease in the otolaryngologic field.

著者

遠藤 廣子 末武 光子 入間田 美保子

雑誌

日本化学療法学会雜誌 = Japanese journal of chemotherapy (ISSN:13407007)

巻号頁・発行日

vol.47, no.1, pp.30-34, 1999-01-25

被引用文献数

24