著者

末武 光子 入間田 美保子 高橋 辰 沖津 尚弘 大山 健二

出版者

Japan Otological Society

雑誌

Otology Japan (ISSN:09172025)

巻号頁・発行日

vol.10, no.2, pp.89-94, 2000-05-25 (Released:2011-06-17)

参考文献数

5

被引用文献数

5

---

Mucoud otitis is known to be caused by mucoid typeStreptococcus pneumoniae, and the most of them are serotype 3. As the result of the development of antibiotics this bacteria has once been regarded as an unimportant pathogen. However recently, there are found severe cases in which this pathogen is responsible.During the period from January 1998 to July 1999, we have treated 25 cases in which the mucoid typeStreptococcus pneumoniaewas isolated.Based on these experiences, we summarized the current status of the mucoid otitis media as follows.1. The distribution of patients suffering from mucoid otitis medid ranged infants to elderly people. 2. The patients presented with symptomes, such as severe earache, headache, high fever, profuse otorrhea, aggravation of sensorineural hearing. 3. The relief of the symptomes is usually better and earlier when penicillin was selected as a first choice, while when cephem antibiotics were selected, healing of the otitis media tend to be delayed. 4. As 13 out of 14 strains isolated in 1999 were found to be penicillin-insensitiveStreptococcus pneumoniae (PISP) withpbp2xgene, it is conceivable that the resistance of this pathogen against cephem is under a rapid progress, probably due to abuse cephem in the past in this country. 5. The antibiotics of the first choice against mucoid otitis media is penicillin. If the pathogen would acquire penicillin resistance, treatment of mucoid otitis media may become as difficult as it used be in old days of preantibiotics. We should pay enough attention to this disease as an important reemerging infectious disease in the otolaryngologic field.

著者

小林 俊光 八木沼 裕司 末武 光子 高橋 由紀子

出版者

耳鼻咽喉科展望会

雑誌

耳鼻咽喉科展望 (ISSN:03869687)

巻号頁・発行日

vol.40, no.3, pp.342-346, 1997-06-15 (Released:2011-03-18)

参考文献数

18

---

耳管閉鎖不全に基づく耳疾患には, 鼓膜に異常のない耳管開放症のほかに, 中耳真珠腫, 滲出性中耳炎, 中耳アテレクタシスなどがある。中耳真珠腫の25%に耳管閉鎖不全に基づく鼻すすり癖が誘因と考えられる症例が認められた。診断に当たっては, 耳管閉鎖不全の存在を疑うことが重要であり, とくに真珠腫では両側耳に病変のある弛緩部型真珠腫, 滲出性中耳炎では鼓膜内陥の強い貯留液の少ない症例においては, 鼻すすり癖の綿密な問診と鼻すすり時の鼓膜内陥また中耳腔陰圧形成の確認が必要である。治療に当たっては, 鼻すすり癖と病変の関係を患者に理解させることが, 再発防止に重要である。重症例では開放耳管に対する治療が主病変の治療とともに必要であり, 開放耳管の効果的治療法の開発が待望される。

著者

遠藤 廣子 末武 光子 入間田 美保子

雑誌

日本化学療法学会雜誌 = Japanese journal of chemotherapy (ISSN:13407007)

巻号頁・発行日

vol.47, no.1, pp.30-34, 1999-01-25

被引用文献数

24