著者
小林 星太 大木 孝弘 金谷 祐希 寺沢 明宏 徳久 宏子 菅 幸生
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.48, no.5, pp.212-217, 2022-05-10 (Released:2023-05-10)
参考文献数
11

Terminal cancer patients receiving home care medicine require emergency home visits by a medical professional during sudden changes in symptoms. However, the actual situation of these visits by health insurance pharmacists is yet to be clarified. Therefore, in this survey, we retrospectively analyzed the actual situation of emergency home visits to terminal cancer patients by the Tokuhisa-chuo Pharmacy during a 1-year period in 2020. We included 134 emergency home visits conducted for 76 terminal cancer patients. Results indicated that emergency home visits tended to be more frequently performed closer to the patient’s end-of-life stage. Patients’ symptoms during emergency home visits were predominantly pain, dysphagia, fever, and respiratory and gastrointestinal symptoms. Drugs such as opioids, gastrointestinal drugs, antimicrobials, and antipyretic analgesics were frequently used to control these symptoms. In particular, the number of emergency home visits intending to manage pain and provide opioids significantly increased in the week before death. This survey clarified the need for emergency home visits by health insurance pharmacists in cancer patients receiving home care medicine in their dying stages.
著者
小林 星太 大木 孝弘 徳久 宏子 菅 幸生
出版者
一般社団法人 日本老年薬学会
雑誌
日本老年薬学会雑誌 (ISSN:24334065)
巻号頁・発行日
vol.3, no.3, pp.65-69, 2020-12-31 (Released:2021-01-28)
参考文献数
8

Serotonin syndrome refers to the adverse events caused by serotonin-based drugs such as antidepressants. Its clinical manifestations include psychiatric and neurovegetative symptoms. In this communication, we report our experience with an 83-year-old woman receiving antidepressants, who developed subjective symptoms such as heavy sweating, dizziness, and tremor after starting treatment with dextromethorphan. Treatment with antidepressants was continued, but five months later, the patient experienced symptoms of heavy sweating, elevated blood pressure, tremor, and anxiety. In her case, serotonin syndrome was suspected by a pharmacist working in a pharmacy, who promptly carried out early intervention and assisted in the prevention of recurrence. In elderly patients who are prescribed dextromethorphan and antidepressants, the possibility of occurrence of serotonin syndrome needs to be taken into consideration in the follow-up of the clinical course.
著者
大木 孝一 和田 公平 山本 祐三 牧本 一男 高橋 宏明
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.86, no.12, pp.1757-1762, 1993-12-01 (Released:2011-11-04)
参考文献数
6
被引用文献数
2 4

Actinomycosis is a chronic purulent granulomatous disease caused by actinomyces, an organism which is often present in man. Patients with a chronic clinical course have been on the increase in recent years, and differentiating this disease from tumor is often necessary when the mass is in facial and cervical regions other than the oral cavity and jaw. We report two cases of actinomycosis in the face and neck.Case 1: A 54-year-old man complained of a swelling in the anterior part of the neck. A mass 65 × 70 mm with redness of the skin was noted at his first visit. The mass was of platelike consistency with a smooth surface closely adherent to the surrounding tissue. The tuberculin test was negative. A malignant tumor was considered, so percutaneous needle biopsy was performed, but no significant abnormality was found. Antibiotics were given by drip infusion, and the mass disintegrated. Yellow viscous pus containing light gray granules was discharged to form a fistula.Case 2: A 40-year-old man developed a swelling in the left cheek. A ping pong ball-sized mass of plate-like consistency with redness was noticed at his first visit. A fistula formed in the oral cavity on the left, and pus was discharged from it. Plain CT revealed an isodense lesion in the left cheek, with no connection to the maxillary sinus.Actinomyces is anaerobic, so it was not detected by culture in either case. Histopathological examinations of actinomycotic granules was useful in the diagnosis.The treatment consists mainly of drainage by incision of the lesion and administration of antibiotics, especially penicillin.