2 0 0 0 OA 八戸市民の毛髪中水銀濃度と魚介類摂取について
- 著者
- 吉田 稔 久保 涼子 三迫 智佳子 鈴木 志乃舞 工藤 綾香 蜂谷 紀之 安武 章
- 出版者
- 一般社団法人 日本微量元素学会
- 雑誌
- Biomedical Research on Trace Elements (ISSN:0916717X)
- 巻号頁・発行日
- vol.24, no.3, pp.170-175, 2013 (Released:2013-10-29)
- 参考文献数
- 13
This survey aimed to determine the levels of mercury in the scalp hair of residents of Hachinohe City in relation to their fish/seafood consumption to assess the risk of methylmercury exposure among the population. A total of 363 individuals (73 males and 290 females) residing in Hachinohe City (Aomori, Japan) provided scalp hair samples and completed a questionnaire. The geometric mean levels of mercury in the scalp hair were 2.52 and 1.91 μg/g in males and females, respectively, and 1.36 μg/g in females aged 15-49 years (n=80). The percentage of females of this generation with a hair mercury level above 2.2 μg/g (corresponding to the WHO's provisional tolerable weekly intake for methylmercury) was 21%, which was lower than the mean of 25% for residents of 10 regions across Japan. The Hachinohe residents consumed a mean of 108 g/day of fish/seafood (which was higher than the mean of 80.2 g/day for the overall Japanese population), consisting mainly of salmon, squid, mackerel, saury, and Atka mackerel. These results demonstrated that the hair mercury level of the residents of Hachinohe City was not so high as the higher consumption of fish/seafood compared with the national average, indicating that the risk of methylmercury exposure through increased fish/seafood consumption among Hachinohe City residents is not particularly high compared with the national level.
1 0 0 0 OA 発達期脳へのメチル水銀毒性に対する食物由来セレン化合物の抑制機構に関する研究
セレンは必須微量元素で、水銀化合物の毒性防御作用が期待される本研究では、自然界に存在する毒性の低いセレンであるセレノメチオニンがラット新生仔の発達期の脳で直接メチル水銀の毒性を防御することを世界で初めて報告した(Env Sci & Tech 2013)。歯クジラ類は、比較的高濃度の水銀を体内に蓄積するが、無機化能力が高く、無機化された水銀は、非活性で無毒なセレン化水銀に変化し筋細胞内に残留していることが示唆された。捕鯨の町の住民の血液試料中の水銀とセレン濃度は有意な正の相関を示し、セレンが住民における水銀の毒性の防御の役割を果たしている可能性が示唆された。