著者

布施 養善

出版者

一般社団法人 日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.24, no.3, pp.117-152, 2013 (Released:2013-10-29)

参考文献数

222

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Iodine is a chemical element with atomic number 53 and one of the most valuable natural resources among the halogen elements. One third of all iodine in the world is produced in Japan. Japan has been regarded as an iodine-sufficient or even excessive country because Japanese has been consuming traditionally large amounts of iodine largely through the intake of seaweed. However, there is no national data on iodine nutrition and its relation to diseases. In this review, a variety of aspects of iodine and also iodine status in Japan is discussed.

著者

玉利 祐三 土屋 和幸

出版者

一般社団法人 日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.15, no.3, pp.248-258, 2004 (Released:2005-04-08)

参考文献数

20

被引用文献数

3

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Lithium content of the ocean fish has been investigated for estimating the intake of lithium, which was known as an element being used to a medicine (lithium carbonate) for the remedy of manic-depressive psychosis. In this study, fish (184 samples) was classified commercially into three types; raw fish (n=95), dry fish (n=70) and canned fish (n=19). Lithium content was determined by flame photometry after the decomposition of a fish sample (∼ 2g) with the mixture of nitric and perchloric acids. In the raw fish, lithium content was obviously higher in a sardine group (264 ± 186 ng/g in the range of 67 ∼ 934 ng/g, n=51) than in the other fish group (38 ± 28 ng/g in the range of 11 ∼ 86 ng/g, n=44, at wet-weight basis). Especially in the sardine group, the content was higher in anchovy (407 ± 167 ng/g, n=25) than in others (e. g., big-eye sardine; 85 ± 12 ng/g, n=11 and Japanese pilchard; 157 ± 43 ng/g, n=6, at wet-weight basis). In addition to the sardine group (anchovy, pilchard, sardine and blue sprat) rich lithium was found in the head (40 ∼ 66% of total lithium), compared with the eyes (0.1 ∼ 1%), internal organ (1 ∼ 9%), body (10 ∼ 33%) and back bone (15 ∼ 36%) of the fish. On the other hand, in dry fish, lithium was rich in the anchovy of “Niboshi” (5390 ng/g, as mean, n=30, at dry-weight basis) among dry sardine; manufactured as “Niboshi”, “Tazukuri”, “Maruboshi”, “Namaboshi” and “Chirimen” named for depending on their different drying-treatments in Japan. Lithium content of raw anchovy, 407 ± 167 ng/g (n=25) at wet-weight basis, was converted to 1770 ± 727 ng/g (n=25) at dry-weight basis, and the value was close to 2440 ± 657 ng/g (n=9) of dry anchovy as “Tazukuri” at dry-weight basis. The lithium content of canned sardine soaked with oil (sardine fillet: 246 ± 135 ng/g, n=15, at wet-weight basis) was close to that with water (sardine fillet: 123 ± 62 ng/g, n=3, at wet-weight basis), and was almost equal to that of raw sardine group (264 ± 186 ng/g, n=51, at wet-weight basis). It was concluded that anchovy and sardine, regardless of raw, dry or canned fish and of different ocean of the fish collected, were good material for the intake of lithium.

著者

金子 哲夫 山脇 奈見子

出版者

一般社団法人 日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.15, no.3, pp.235-242, 2004 (Released:2005-04-08)

参考文献数

28

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In Japan, Recommend Dietary Allowance (RDA) and Dietary Reference Intake (DRI) of trace elements were first specified in 1999. More than 4, 000 human milk samples were collected during 1998 and 1999 from Japanese lactating women at different postpartum and were individually analyzed for composition of nutrients including trace minerals. The latest data on zinc, copper, and selenium concentrations was summarized. The daily intake status of the trace elements by breast- and bottle-fed infants was investigated in reference to the 6th edition of RDA and DRI for Japanese nation.

著者

吉田 稔 久保 涼子 三迫 智佳子 鈴木 志乃舞 工藤 綾香 蜂谷 紀之 安武 章

出版者

一般社団法人 日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.24, no.3, pp.170-175, 2013 (Released:2013-10-29)

参考文献数

13

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This survey aimed to determine the levels of mercury in the scalp hair of residents of Hachinohe City in relation to their fish/seafood consumption to assess the risk of methylmercury exposure among the population. A total of 363 individuals (73 males and 290 females) residing in Hachinohe City (Aomori, Japan) provided scalp hair samples and completed a questionnaire. The geometric mean levels of mercury in the scalp hair were 2.52 and 1.91 μg/g in males and females, respectively, and 1.36 μg/g in females aged 15-49 years (n=80). The percentage of females of this generation with a hair mercury level above 2.2 μg/g (corresponding to the WHO's provisional tolerable weekly intake for methylmercury) was 21%, which was lower than the mean of 25% for residents of 10 regions across Japan. The Hachinohe residents consumed a mean of 108 g/day of fish/seafood (which was higher than the mean of 80.2 g/day for the overall Japanese population), consisting mainly of salmon, squid, mackerel, saury, and Atka mackerel. These results demonstrated that the hair mercury level of the residents of Hachinohe City was not so high as the higher consumption of fish/seafood compared with the national average, indicating that the risk of methylmercury exposure through increased fish/seafood consumption among Hachinohe City residents is not particularly high compared with the national level.

著者

玉利 祐三

出版者

一般社団法人 日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.16, no.3, pp.250-257, 2005 (Released:2006-04-20)

参考文献数

26

被引用文献数

1

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Lithium carbonate is known as medical supplies for the remedy or prevention of manic-depressive psychosis. Blood lithium concentrations of their patients generally should be monitored during their hospital-treatments not to beyond the toxic concentration level of lithium. When heparin is usually added to a blood sample for preventing the blood-coagulation, impurity lithium of the reagent gives a positive error for the determination of lithium concentration of the blood. In this work the lithium concentration was determined by flame photometry after the decomposition of a sample with nitric-perchloric acids or hydrofluoric-nitric-perchloric acids for food samples. In the chemicals used for anticoagulant it was found that sodium citrate, heparin sodium salt and EDTA-2Na contained high amounts of lithium as impurity; 422, 221and 204 ng/g, respectively, whereas lithium was not detected in EDTA-4H and citric acid. Impurity lithium content of chemicals of general salt of sodium, potassium, magnesium and calcium were also tested; there was a fact that considerable amounts of lithium, 39500 and 14000 ng/g, existed in high purity of calcium metal and its carbonate. The Li/Ca ratio of the content of calcium salt (chemicals, n=36) was almost constant, and there was a good correlation between lithium and calcium content. The same tendency of the constant ratio of Li/Ca for the chemicals was also found in natural carbonate minerals of calcite, dolomite and aragonite, and biological materials of human milk, human serum, mammalian bone and oyster shell. On the other hand, lithium concentrations of plasma of healthy Japanese and Korean female were investigated, and the relationship between plasma lithium concentration and daily dietary lithium intake of the healthy people at urban district and village near seashore were also investigated in Korea. There was no significant difference between dietary lithium intake and plasma lithium concentration for the healthy people. Plasma lithium concentration was almost constant to be 11±2 ng/g (n=164) for healthy people.