著者

山際 三郎 城田 知訓 山内 希美 宮田 知幸 児玉 直樹 宮下 剛彦 河合 寿一 加藤 正夫

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.67, no.3, pp.173-178, 2004 (Released:2010-04-30)

参考文献数

5

被引用文献数

1

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We investigated the influences of hot-spring bathing on the incidences of abortion and premature birth using questionnaires returned from 768 puerperal in-patients.These patients were classified into four groups: 24 taking a hot-spring bath daily (group 1), 134 taking a bath with additives (group 2), 178 taking a plain water bath daily (group 3), and 35 taking a shower daily (group 4).The incidence of threatened abortion among the ambulatory patients in each group was 4.2% for group 1, 11.9% for group 2, 9% for group 3, and 2.9% for group 4.The incidence of threatened abortion among the hospitalized patients in each group was 4.2% for group 1, 6.7% for group 2, 4.5% for group 3, and 8.6% for group 4.The incidence of threatened premature birth among the ambulatory patients in each group was 12.5% for group 1, 17.2% for group 2, 15.7% for group 3, and 14.3% for group 4.The incidence of threatened premature birth among the hospitalized patients in each group was 0% for group 1, 7.5% for group 2, 3.4% for group 3, and 2.9% for group 4.The incidence of vaginitis among the patients in each group was 50% for group 1, 43.4% for group 2, 46.6% for group 3, and 44.1% for group 4.The incidence of premature rupture of membrane (PROM) among the patients in each group was 4.2% for group 1, 21.1% for group 2, 12.9% for group 3, and 22.9% for group 4.The incidence of premature birth among the patients in each group was 0% for group 1, 3% for group 2, 2.8% for group 3, and 2.9% for group 4.Among the 42 multiparas experiencing single delivery and being treated for threatened abortion, those who for more than 10 minutes daily showed a significant difference from ambulatory patients being treated for threatened abortion that required hospitalization.Many of the 63 primiparas who did not use a labor accelerating medicine but bathed for more than 10 minutes daily delivered their babies within 1000 minutes.ConclusionThe above suggests that pregnant women may bathe in hot-springs without problem but bathing for less than 10 minutes is recommended during early stage of pregnancy.

著者

宮田 知幸

出版者

岐阜大学

雑誌

岐阜大学医学部紀要 (ISSN:00724521)

巻号頁・発行日

vol.51, no.1, pp.157-162, 2003-03-31

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Purpose Intercellular adhesion molecule-1 (ICAM-1) expressed on colorectal carcinoma was reported to be related to grades of its malignancy. The purpose of this study was to investigate whether the distribution of ICAM-1 expression in colorectal carcinoma correlated with their pathological findings and prognoses after surgical resection. Materials and Methods Forty-two patients with colorectal carcinoma underwent surgical resection. Their ICAM-1 in colorectal carcinoma was stained with immunohistchemical method. We compared the distribution of ICAM-1 with pathological stages, tumor diameter, tumor infiltration depth and vessels involvement, lymph node and liver metastasis, peritoneal dissemination, and survival after surgical resection, respectively. Results The distribution of ICAM-1 expression were classified into three types : Type D or diffuse type, Type I or intermediate type and Type S or sporadic type. Tumor diameter in Type D, I and S were 5.9±1.4, 9.2±2.5 and 3.3±1.2cm, respectively (p<0.0001). Tumor diameter in patients (DL : n= 6) who survived longer than 5 years after surgery and those (DD : n=14) who died with in 5 years, in Type D and those (SL : n=10) who survived longer than 5 years and those (SD : n=4) who died within 5 years, in Type S were 5.1±1.3, 6.2±1.4, 2.9±1.0 and 4.1±1.1cm, respectively (p<0.0001). The grade of lymph node metastasis was SD, DD, SL and DL in order (p<0.0089). SL was significantly different from DD (p<0.0349). There were no significant relations between the distribution of ICAM-1 expression and other parameters. Conclusion These results suggest that the distribution of ICAM-1 expression is useful as an index for survival of the patients with surgical resection of colorectal carcinoma.

著者

山内 希美 宮田 知幸 岡田 将直 仁田 豊生 河合 寿一 宮下 剛彦

出版者

Japan Surgical Association

雑誌

日本臨床外科学会雑誌 = The journal of the Japan Surgical Association (ISSN:13452843)

巻号頁・発行日

vol.65, no.3, pp.751-755, 2004-03-25

被引用文献数

6 3

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症例は78歳,男性.平成13年5月5日から全身倦怠感,食欲不振が出現し下血を認めたため当院内科を受診した.カルチノイド症状は認めなかった.大腸内視鏡検査で下部直腸に1型腫瘍を認め,生検で低分化腺癌もしくは未分化癌と診断された.腹部CT検査で多発肝転移を認めた.腹会陰式直腸切断術とリザーバー留置術を行った.免疫組織染色のクロモグラニンA, NSEで陽性像を示し,内分泌細胞癌と診断された.化学療法を開始したが,平成14年1月5日死亡した.内分泌細胞癌は予後不良であり,低分化腺癌や未分化癌との鑑別が困難である.直腸内分泌細胞癌の本邦報告例は自験例を加えて37例であり,術前から肝転移を認めた症例は22例であった.早期癌の症例は5例あるがいずれも予後は不良であり壁深達度と予後の関連はないと考えられた.内分泌細胞癌は外科的切除が第一選択と考えられるが,予後は不良で何らかの補助療法が必要である.