著者
小林 泰輔 岡田 昌浩 寺岡 正人 中村 光士郎
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.65, no.6, pp.453-459, 2006 (Released:2009-06-05)
参考文献数
15
被引用文献数
1

Cogan's syndrome is primarily diagnosed based on subsequent episodes of an inflammatory eye disease and rapidly progressive, usually sequential bilateral loss of audiovestibular function. Since there are still no specific tests for the syndrome, it is difficult to diagnose Cogan's syndrome in the early stage before the emergence of both eye and audiovestiubular symptoms. We present a case of a 34-year-old woman who complained of vertigo and bilateral hearing loss. Magnetic resonance imaging (MRI) of the inner ear was performed before the emergence of keratitis. MRI on the 23rd day after onset of hearing loss revealed a slightly high intensity on TI-weighted images in the right vestibule, which showed profound hearing loss. On the 54th day after onset, high signal intensity was noted in the right cochlea, the vestibule, and lateral semicircular canal on Tl-weighted images, but no enhancement. The high signal intensity disappeared seven months after onset, but there was no defect of inner ear signs on the T2-weighted images. A high signal of the inner ear on T1-weighted images is not a specific sign of MRI in Cogan's syndrome, since it is sometimes encountered in the inner ear of labyrinthitis, bleeding in patients with leukemia, and intralabyrinthine schwanoma. However, MRI could be a possible method for the early diagnosis of Cogan's syndrome because this finding might be recognized before the onset of eye symptoms.
著者
行本 敦 橋本 悠 花山 雅一 小幡 善保 谷平 哲哉 清家 裕貴 岡本 傳男 市川 幹郎 寺岡 正人
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.104, no.7, pp.1460-1463, 2015-07-10 (Released:2016-07-10)
参考文献数
7
被引用文献数
1 1

症例は81歳,女性.呼吸困難感を主訴に来院した.来院時,舌の著明な腫大がみられた.高血圧に対し,エナラプリルマレイン酸を内服していた.同薬による血管性浮腫を疑い,同薬を中止し,入院とした.喉頭の浮腫は軽度であったため,7 Fr経鼻エアウェイを挿入し,気管切開は行わず,経過観察とした.72時間後には舌の腫大は改善し,発語も明瞭であった.同薬を中止し,経過をみているが,再燃はみられていない.