著者
古川 朋靖 渡辺 道隆 山川 卓也 正木 義男 加納 昭彦 市川 銀一郎
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.57, no.5, pp.480-486, 1998 (Released:2009-10-13)
参考文献数
15

IntroductionFor transcranial magnetic stimulation of the facial nerve, a magnetic coil is fixed to the temporal region over the nerve. It has been reported that the facial nerve can be stimulated at the distal part of the auditory canal, and it is expected that the peripheral vestibular organs are included in the time-varying magnetic field. We examined the influence of magnetic stimulation on the peripheral vestibular organs using a stabilometer.MethodsExperiments were carried out on 10 healthy adults. Magnetic stimulation was administered to the temporal region including the peripheral vestibular organs and stabilometry was performed before and after stimulation. We used a G5500 system stabilometer (Anima Co.) with a sampling time of 20 msec. and recorded body sway for 60 sec. A Mag lite (Dantec Co.) was used for magnetic stimulation and a Synax ER 1100 (NEC-Sanei Co.) was used as the trigger. The stimulus was set at 4 Hz and stimulation was done 60 times. The output was set at about 40% of 1.9 Tesla (maximum output).ResultsWe analyzed the body sway length, 8-directional body sway velocities, and the power spectrum of the lateral body sway velocity. The total length of body sway and the velocity of lateral sway increased significantly after magnetic stimulation.
著者
正木 義男 渡辺 道隆 古川 朋靖 加納 昭彦 山谷 千恵美
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.57, no.3, pp.297-304, 1998 (Released:2009-10-13)
参考文献数
15
被引用文献数
2 2

IntroductionVasovagal reflex (VVR) is a disease that has received attention in various fields.Recently, researchers have started to clarify its mechanism. Three patients with symptoms probably due to VVR were treated in this department and the Head up tilt test was used to diagnose dizziness due to VVR.PatientsThe three patients included a 21-year-old female (Case 1), a 26-year-old male (Case 2) and a 61-year-old female (Case 3). All three patients had chief complaints of spontaneous dizziness after standing or sitting for 5 to 30 minutes.ResultsThe duration of standing before the onset of positive findings was 9.5 minutes in Case 1 and 11 minutes in Case 2. In Case 3, positive findings were obtained 9.5 minutes after isoproterenol administration.DiscussionAll three patients showed spontaneous dizziness in either the standing or sitting position and the results of the Head up tilt test were positive. Therefore, dizziness seemed to be due to VVR in these patients. The instantaneous decrease in blood volume due to paradoxical activation of the vagus nerve may have induced dizziness, loss of consciousness and faintness. Because of severe patient stress during the Head up tilt test, this examination should be indicated only in those who are strongly suspected of VVR.
著者
渡辺 行雄 水越 鉄理 中川 肇 大井 秀哉 将積 日出夫 安村 佐都紀 中江 公裕 北原 正章 矢沢 代四郎 渡辺 勇
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.50, no.7, pp.1-10, 1991
被引用文献数
9 2

During the past 14 years from 1975 to 1989, two-nation-wide surveys of Meniere's disease have been carried out by the Vestibular Disorders Research Comittee of Japan, supported by the Ministry of Health and Welfare of Japan. However, an epidemiological case-control-study including normal subjects has not yet been performed by this committee.<BR>In this third survey, therefore, 148 patients with definite Meniere's disease, 138 with non-Meniere vertigo, 113 with rhinolaryngological disorders, and 165 normal control subjects were collected by the 16 mem-bers of the Research Committee from June 1990 to November 1990. The controls were selected to match as closely as possible the sex, age and location of the Meniere's disease patients.<BR>The characteristic epidemiological features of Meniere's disease in Japan were :<BR>1) Sex-ratio : 63 males to 85 female.<BR>2) Age-distribution : Peak at 40-49 years for males and 30-39 years for females.<BR>3) Season and Time of Onset : Often initial vertigo attacks occurred in the afternoon or in the morning.<BR>4) Occupational Distribution : There was a higher incidence of Meniere's disease among technicians or white-collar workers than among farmers, laborers engaged in blue-collar work, as in the 1st and 2nd surveys. However, the number of house-wives was lower in this 3rd survey.<BR>5) Personal characteristics : In patients with Meniere's disease, precisionism and neurosis were more frequently observed than in non-Meniere's vertigo.<BR>6) Preceding Events : Mental and physical fatigue before vertigo attacks was frequent in Meniere's disease patients.<BR>These epidemiological features reconfirm that the occurrence of vertigo attacks in Meniere's disease is influenced much more by individual factors than by environmental factors, as was found in the 1st and 2nd Nation-wide surveys. However, a marked difference in sex ratio with female preponderance was found in the 3rd survey.<BR>The incidence of bilateral Meniere's disease was 16.2% (24/148), higher than in the 1st and 2nd surveys.
著者
一條 宏明 朴沢 二郎 藤原 文明 西村 哲也
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.47, no.4, pp.414-419, 1988
被引用文献数
1

This study was performed to determine the influence of repeated rotatostimulation on the vestibulo-ocular reflex. Three figure skaters and three ballet dancers with careers of more than 10 years were examined by two rotation tests with Contraves' computerized rotary chair on the same day. The two tests were Trapezoid Rotation (TR) test (±2, 4, 6, 8, 10°/sec<SUP>2</SUP>, 10″) and Sinusoidal Harmonic Acceleration (SHA) test (0.01, 0.02, 0.04, 0.08, 0.16 Hz).<BR>1) The TR test showed that skaters and ballet dancers had equivalent values of VOR-Gains as the average of healthy untrained subjects.<BR>2) VOR-Gains measured by the SHA test were lower than the average of healthy untrained subjects.The difference was most clearly noticed with rotations of 0.16Hz.<BR>3) No subjects showed vestibular asymmetry, except for one subject who showed directional preponderance to the left.<BR>4) Nystagmus duration measured by the TR test was within the normal range.
著者
山本 悦生 水上 千佳司 磯野 道夫 大村 正樹 広野 喜信
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.49, no.Suppl-6, pp.28-30, 1990 (Released:2009-06-05)
参考文献数
4

The three-dimensional imaging used so far has processed digitalized information on the morphology of organs by the computer graphics technique. However, the conventional method has not been used clinically, because the processing of information has been inadequate.We observed the external aperture of the vestibular aqueduct in vivo using three-dimensional imaging by the surface reconstruction method. The width was measured in normal and diseased ears. Significant narrowing was observed in patients with Meniere's disease, while no difference in width was noted between normal subjects and those with chronic otitis media.This technique can be used to examine not only on the vestibular aqueduct but also other structures in the temporal bone. It should be useful in clarifying the pathophysiology of inner ear diseases and also in the surgical treatment.

1 0 0 0 OA 前庭代償

著者
北原 糺
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.59, no.2, pp.103-111, 2000 (Released:2009-06-05)
参考文献数
49

Vestibular compensation consists of the following stages: the inhibition of the contralesional medial vestibular nucleus (contra-MVe) activities at the acute stage after unilateral labyrinthectomy (UL) and the recovery and maintenance of the ipsilesional MVe (ipsi-MVe) spontaneous activities at the chronic stage after UL. In this paper, we reviewed molecular mechanisms of vestibular compensation in the central vestibular system by means of several morphological and pharmacological approaches in rats. Based on our examinations, we propose the following hypothesis. At the acute stage after UL, the activated neurons in the ipsi-MVe project their axons into the flocculus to inhibit the contra-MVe neurons via NMDA receptor, nitric oxide (NO), acetylcholine (Ach) and/or GABA-mediated signaling, resulting in the restoration of balance between intervestibular nuclear activities. At the chronic stage after UL, the flocculus depresses the inhibitory effects on the ipsi-MVe neurons via protein phosphatase 2A (PP2A) β, protein kinase C (PKC) and/or glutamate receptor (GluR) δ-2, to help the recovery and maintenance of the ipsi-MVe activities.
著者
武田 憲昭
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.59, no.2, pp.93-102, 2000 (Released:2009-06-05)
参考文献数
53
被引用文献数
2

In the acute period, the goal of drug therapy for vertigo is suppressing the sensation of vertigo, preventing vomiting and helping restore normal balance. Intravenous injection of NaHCO3 is effective against the sensation of vertigo. Since histamine H1-receptors are involved in vomiting that is associated with vertigo, antihistamines could prevent it. Benzodiazepines may restore normal balance by stimulating the initial develop-ment of vestibular compensation, in addition to their antianxiety effects. In the chronic period, vasodilators such as diphenidol or betahistine could prevent recurrent attacks of vertigo. Benzodiazepines may act on the limbic system and relieve psychotic triggering of vertigo attacks. Meniere's disease, in which the primary pathology is endolymphatic hydrops, is specifically managed by an osmotic diuretic, isosorbide. Steroids may be helpful in patients with vestibular neuronitis.
著者
宇野 敦彦 中川 あや 堀井 新 武田 憲昭 久保 武
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.65, no.4, pp.213-222, 2006 (Released:2009-06-05)
参考文献数
52

Motion sickness is induced by unusual patterns of spatial information input, but not by a simple strong acceleration. Thus, in the process of the development of motion sickness, the disturbance of spatial orientation is noticed somewhere in the brain, leading to the expression of autonomic signs and symptoms. What part of the brain plays this key role?Peripheral vestibular input has repeatedly been proven to be necessary for motion sickness, even for visually-evoked motion sickness. The vestibular nucleus in the brain stem where spatial information including visual and somatosensory as well as vestibular inputs converge, is the primary candidate for this key structure. In the higher brain, the limbic system, particularly the amygdala, is another candidate. In our rat animal model, bilateral amygdala lesions significantly suppressed motion sickness signs, whereas hippocampus lesions did not. Using cFos protein expression as a marker for neuronal activation, we also showed that the central nucleus of the amygdala was activated by vestibular information during the hypergravity stimulation that induced motion sickness in rats.Involvement of the amygdala may explain some characteristic features of motion sickness, such as its diversity of signs ranging from sympathetic to parasympathetic, and its conditioned occurrence where by some susceptible persons become sick even in motionless vehicles.
著者
松木 則夫 田中 大祐
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.60, no.1, pp.3-6, 2001 (Released:2009-06-05)
参考文献数
10

Suncus murinus belongs to insectivora and has been developed as a laboratory animal in Japan. It is relatively small in size (male: 50-70g, female: 30-50g), and there are no problems in the handling, housing and breeding of the animal. We have found that administration of emetogenic drugs, X-ray irradiation and oscillation easily causes emesis in this animal. Since simple reciprocal shaking (frequency: 1 Hz, amplitude: 4cm) is enough to induce vomiting within as short as 2 min, Suncus murinus is currently the most sensitive animal to motion sickness. Information conserning the purchase and special animal chow is available at the Central Institute for Experimental Animals.Our knowledge of emesis and motion sickness is still very poor. The presence of a "vomiting center" and a "CTZ: chemoreceptor trigger zone" were proposed about a half century ago but substantiating evidence is still lacking. Antiemetic dugs have been developed to reduce the number of vomiting episodes; however, in terms of quality of life, complete blockade of nausea rather than vomiting is desirable. We believe that Suncus murinus will be a useful experimental animal for research on emesis and the development of new antiemetic drugs.
著者
武田 憲昭
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.55, no.4, pp.335-342, 1996 (Released:2009-06-05)
参考文献数
10
被引用文献数
6 6

Neural mechanisms of gaze, vertical and rotatory nystagmus are reviewed. For all eye movements, eye velocity is an oculomotor parameter. Eye velocity signals are transformed by a neural integrator in the brain stem to obtain the eye position signal. A lesion of neural integrator leads to gaze-evoked nystagmus. Vertical nystagmus arises from a lesional or functional tone imbalance, which is due to disruption of the central vestibulo-ocular reflex pathway in the pitch plane. Downbeat nystagmus is caused by lesions between the vestibular nuclei or flocculus. Upbeat nystagmus is caused by lesions in the brachium conjunctivum, the ventral tegmental pathway and the prepositus hypoglossal nucleus. Rotatory nystagmus involves an epicodic ocular tilt reaction, which is a clinical sign of an imbalance of the central vestibulo-ocular reflex in the roll plane. Unilateral infarction of the brain stem leads to rotatory nystagmus.
著者
井須 尚紀 河合 敦夫 桝井 文人
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.63, no.3, pp.183-193, 2004 (Released:2009-06-05)
参考文献数
26

The sensation of rotation derived from the semicircular canal system during a Coriolis stimulus, or cross-coupled rotation, was estimated by an mechanical approach by giving some hypotheses and simplifications on the semicircular canal system. By solving an equation of motion of the endolymph during a Coriolis stimulus with a moderate time course, the rotating angle of the endolymph was obtained, and the sensation of rotation derived from each semicircular canal was estimated. Then, the sensation was integrated in the whole semicircular canal system, which was considered to be composed of three orthogonal semicircular canals. The sensation of rotation derived from the semicircular canal system comes into conflict with those from the otolithic and somatosensory system. The conflict causes an illusion such that the head rotates vertically while keeping inclination at a constant tilt angle. The nauseogenic severity of motion sickness caused by a Coriolis stimulus is enhanced in accordance with the integrated angle of rotation perceived by the illusion.
著者
中村 将裕 石井 正則 近澤 仁志 丹羽 洋二 山崎 ももこ 伊藤 洋
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.63, no.4, pp.335-345, 2004 (Released:2009-06-05)
参考文献数
21
被引用文献数
3 2

Falls and falling accidents occurring in hospitals have become a problem in recent years, and some of those events have been documented to have occurred after patients ingested sleep-inducers (hypnotics). One of the pharmacological actions of hypnotics is muscle-relaxing activity, and it has been clarified in animal studies that this activity causes falls and falling accidents. However, this association has not yet been proven in humans.In this study, conducted in eight healthy adult volunteers, we compared the manifestation of balance disorders after ingestion of four test drugs, consisting of two ultra-short-acting hypnotics (zolpidem and triazolam), a long-acting hypnotic (qazepam) and a placebo (i.e., the control). Zolpidem and qazepam, which are said to express weak muscle-relaxing activity, both caused balance disorders. Also, strong correlations were found between the manifestation of balance disorders after drug ingestion and the plasma concentrations of zolpidem, triazolam and some of the metabolites of qazepam. In addition, in the case of zolpidem, which caused the most severe balance disor-ders, gaze deviation nystagmus was detected. For this reason, it was surmised that balance disorders occurring after ingestion of hypnotics involve some inhibition of the central nervous system, including the cerebellum and brain stem, rather than the mus-cle-relaxing activity of the drugs.Differences were observed among the tested hypnotics in relation to the time of occurrence of balance disorders postmedication and also to the severity of the symp-toms. Accordingly, for the prevention of falling accidents, it is considered necessary that the physician be fully cognizant of the patient's age, medical history and physical condition, as well as not only the characteristics of the hypnotics but also the time-course changes in their concentration in the blood. Then, adequate caution must be applied with regard to the time period in which the patient is in a half-awake state.
著者
正木 義男
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.64, no.1, pp.22-28, 2005 (Released:2009-06-05)
参考文献数
32
被引用文献数
1 1

We encountered a patient who developed dizziness due to the vasovagal reflex (VVR) during the Schellong test (ST).A 32-year-old woman had a chief complaint of dizziness. Present Illness: She had repeatedly since childhood experienced dizziness attacks associated with darkness in front of her eyes immediately after standing up. She easily developed motion sickness. Dizziness continued to occur when she was standing in a bus or train, when she was in the bath, or when she got excited. She was admitted to a hospital in the district and ECG and a blood test were conducted, but no abnormal findings were revealed. Past History: She had bronchial asthma in childhood. She had a gastric ulcer and received drug treatment in january 1997. Family history was unremarkable.She had a positive Schellong test. Immediately after standing up, her pulse rate sharply increased from 94 to 123/min., and 5 min. after standing up, the pulse rate became 127/min. She complained of dizziness immediately before the end of the testing, and the pulse rate and blood pressure measured at the time were 75/min., showing a sharp decline, and 90/55, showing a slight decrease, respectively. Thereafter, she had decreased consciousness and was immediately laid in a supine position. She soon became alert. Blood pressure recovered to 106/62 and the pulse rate to 94. Neural symptoms were absent. Treatment and Clinical Course: Although she developed WR during ST, her condition could be diagnosed as orthostatic dysregulation (OD) because it met the criteria for diagnosis of OD. However, a diagnosis of postural tachycardia syndrome (POTS) was made according to the theory that WR and OD are special types of POTS. She is under medication with an α-receptor agonist agent.Patients are always at risk, although not high, of developing VVR and falling during ST, which may be associated with injury. Therefore, after the experience of the present case in our hospital, we reevaluated the procedures of ST and decided on crite-ria for the discontinuation of the testing to prevent accidents.
著者
時田 喬 柴田 康成 小川 剛 宮田 英雄 大野 道敏
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.52, no.4, pp.602-610, 1993

A new apparatus capable of recording head and eye movements was devised to examine the vestibulo-ocular system. Horizontal and vertical head movements were recorded with a sensor of terrestrial mgnetism. Eye movenments were recorded by an electronystagmographic technique. The transmitted data were stored on a floppy disc and analyzed with a microcomputer in a specially designed program.<BR>1. The apparatus was useful as a tool for recording spontaneous and gaze nystagmus and pursuit and saccadic eye movements in patients with labyrinthine and central disturbances.<BR>2. Transfer function (gain and phase) of the vestibulo-ocular system was calculated with head and eye movements obtained from pseudo-random head oscillation in the dark. In normal subjects, gain with head movements as input signal and eye movements as output signal indicated a frequency-dependent gain enhancement;the phase difference between head eye movements was 180°.<BR>3. The vestibulo-ocular reflex (VOR) induced by the right and left labyrinth were examined with velocity recording of head and eye movements induced by quick head movements to the right and left at intervals of 1 second in the dark. Patients with unilaterl labyrinthine disturbance showed a low amplitude response in head movements toward the affected labyrinth.<BR>4. The integration mechanism in the pursuit system was examined from the velocity recording of eye movements during vertical head oscillation with fixation on a visual target. A patient with primary position upbeat nystagmus caused by nutritional deficiency encephalopathy showed a disturbance of the up neural integrator from velocity signal to position signal in the visual vestibular oculomotor system.<BR>The apparatus was usuful for the examination of the vestibulo-ocular system of patients with vertigo and equilibrium disturbances.
著者
吉田 忠雄 加藤 正大 大竹 宏直 加藤 健 寺西 正明 片山 直美 中島 務
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium research (ISSN:03855716)
巻号頁・発行日
vol.72, no.4, pp.247-253, 2013-08-01
被引用文献数
2

Development of 3-tesla enhanced magnetic resonance imaging (MRI) provides a tool for the visualization of endolymphatic hydrops (EH). This technique was first developed in animal experiments and adapted in patients with inner ear diseases including Menieres disease (MD). Up to the present, we have demonstrated EH in many MD patients. Recently, we have succeeded in obtaining a 3D-real IR-like image even after intravenous standard-dose gadolinium administration. This type of image was named the HYDROPS (HYbriD of Reversed image Of Positive endolymph Signal and native image of positive perilymph signal). The relationship between unilateral MD and EH has not yet been explored. We studied 76 patients with unilateral MD who were evaluated using MRI. The mean age of the subjects was 53.4 years (range 17 to 80 years). Forty-two were women and 34 were men. Symptomatic and non-symptomatic ears were categorized into 4 groups (healthy, 76; possible, 48; Probable, 13; and definite, 15) based on AAO-HNS definitions. MRI was performed 4 hours after intravenous gadolinium administration. Overall, 152 ears were evaluated. EH in the cochlea was present in 57 of 76 symptomatic ears (73.7%) and 34 of 76 (44.7%) non symptomatic ears. Ears with definite MD had EH more frequently in the cochlea than ears in the healthy ears groups. Furthermore, EH in the vestibule with definite MD was larger than ears in any of the other groups. Our reports showed for the first time that there was Ba relationship between the degrees of EH and the stage of MD. Moreover, in fewer than half of unilateral MD patients EH was seen in the cochlea with non-symptomatic ears. EH in healthy ears may be an indicator of bilateral MD. Using MRI to identify this covert EH in asymptomatic patients may offer the possibility of early detection or prevention of MD.
著者
鈴木 衞
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium research (ISSN:03855716)
巻号頁・発行日
vol.65, no.2, pp.91-103, 2006-04-01
参考文献数
90
被引用文献数
3 3

Canalolithiasis and cupulolithiasis have been proposed to be causative mechanisms of BPPV. Anatomical and physiological features of otoconia are reviewed. Three layers, the columnar fibers, gelatin membrane, and otolithic membrane, are known as overlaying structures on the macular sensory epithelia. The supporting cell plays an essential role in otoconial formation. It secretes granules containing calcium as a precursor of otoconia. A number of proteins are involved in the production and growth of otoconia, such as Otoconin-90 and CB-D28K. Alterations of the endolymphatic environment, ototoxic drugs, carbonic anhydrase, hormones, aging, or gene mutation lead to degeneration or deformity of otoconia. Hydrodynamic and physiological features of otoconia existing within the semicircular canal or attaching to the cupula have been studied using mathematical models and amphibian semicircular canals. These studies showed that canalolithiasis is potentially the most relevant mechanism of BPPV in terms of the long latency and short duration of nystagmus. Human temporal bone sections had been studied to demonstrate deposits on the cupula or within the canal lumen. Otoconia were also found in the posterior canal lumen that was opened during canal plugging surgery. Clarification of the basic characters of otoconia is essential for elucidating the clinical picture of BPPV.
著者
有國 富夫
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium research (ISSN:03855716)
巻号頁・発行日
vol.62, no.4, pp.284-301, 2003-08-01

Recently, many functional areas have been identified in the parietal cortex of the brain in monkeys, and owing to this, cytoarchitectonic subdivision has been elaborated in the monkey parietal cortex. This review deals with sulcal patterns of the parietal lobe in human and monkey brains, and corticocortical connections of both neurophysiologi-cally defined regions and cytoarchitectonic areas of the parietal cortex in monkeys. The author proposes that the transverse occipital sulcus is a boundary between the parietal and occipital cortices in the human brain. A brain map of the monkey is presented. The parietal cortical areas are subdivided into somatosensory, eye movement related, hand or upper limb movement related, vestibular, and auditory areas, according to neu-rophysiologically defined functions of individual cortical areas. The somatosensory system contains areas 3a, 3b, 1, 2, 5, 7b, and SII: S1 projects to motor and premotor areas and somatosensory association areas project to premotor areas, the prefrontal, temporal, and limbic cortices, and the hippocampus. The eye movement system is composed of areas 7a, LIP, and PIP: It receives input from visual and temporal cortices and sends output to premotor areas, the prefrontal cortex, and the hippocampus. Hand movements are mediated in areas AIP, VIP, CIP, MIP, PEc, and V6A: These areas receive afferents from somatosensory areas, visual and temporal cortices and send efferents to the ventral premotor area. The vestibular functions are executed by coordination of areas 3aNV, 3aHV, 2NV, Ri, and VPS: These areas reciprocate with the cingulate cortex and insula and project to the ventral premotor area, SWA, and frontal eye field. The auditory system involves areas VIP and LIP: It receives afferents from the superior temporal sulcal cortex and sends efferents to the premotor area, frontal eye field, and prefrontal cortex.
著者
藤原 文明 朴沢 二郎 新川 秀一 一條 宏明 西村 哲也
出版者
Japan Society for Equilibrium Research
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.49, no.2, pp.263-270, 1990

Delayed endolymphatic hydrops (DEH) was proposed by Nadol (1975) and Schuknecht (1976) as a pathological diagnosis. Because of severe hearing loss, the presence of endolymphatic hydrops (EH) cannot be demonstrated by the glycerol test or electro-cochleography. This paper discusses a clinical method of examining EH in this disease. The authors' earlier study, reported in Acta Otolaryngol (Stockh) suppl. 435 (1987), showed that EH in Meniere's disease could be detected not only by audiometry but also by the trapezoid rotation test. The demonstration of ipsilateral labyrinthine preponderance (LPi) by this rotation test is a useful indicator of the development of EH. The authors performed this rotation test in seven patients who satisfied Schuknecht's criteria of DEH by careful history taking and audiometry, and LPi was detected in five of them, especially before the onset of vertigo. It was concluded that the detection of LPi by the trapezoid rotation test should be added to the tests used for the exact diagnosis of DEH.