著者

山田 大輔 東堀 紀尚 福岡 裕樹 鈴木 聖一 川元 龍夫 森山 啓司

出版者

THE JAPANESE SOCIETY FOR JAW DEFORMITIES

雑誌

日本顎変形症学会雑誌 (ISSN:09167048)

巻号頁・発行日

vol.22, no.1, pp.12-19, 2012-04-15 (Released:2012-09-14)

参考文献数

28

被引用文献数

1 1

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Facial morphology improvements are obtained following two-jaw surgery in mandibular protrusion patients. Changing external nasal morphology does not always lead to good results in all patients. In this study, using 3-dimentional computed tomography (3D-CT), we examined the changes of external nasal morphology of patients who had undergone two-jaw surgery to correct mandibular protrusion. Seven adult patients (5 male; 2 female) who had been treated by two-jaw surgery associated with upward transposition of the posterior maxilla were enrolled in this study. 3D analysis software superimposed 3D-CTs of the pre-operative and post-operative stages (at least 6 months after surgery) on the hard tissue surfaces. We employed the 3D coordinate system constructed by Frankfort horizontal (FH) plane, the frontal plane incorporating the orbitals on both sides and the sagittal plane intersecting at the midpoint between the orbitals. After superimposition, soft tissue images of 3D-CT were reconstructed and changes in external nasal morphology were three-dimensionally analyzed. 3D geographical analysis, linear and angular measurements were performed for the most inferior points on the nasal alar (LBi, RBi) on bilateral sides, the most anterior point on the nose (Prn), the most anterior point on the columella of the nose (Cm), the most posterior superior point on the nasolabial curvature (Sn) and the most anterior point on the convexity of the upper lip (Vu). Correlation of hard tissue and soft tissue changes were statistically analyzed by Spearman's rank correlation analysis.LBi and RBi moved anterior according to the anterior movement of point A. Increase in distance of both LBi and RBi and angle of LBi-Prn-RBi were observed. We found significant increase in the area of external nasal aperture. Positive correlation was seen between the anterior movement of point A and the distance of LBi and RBi.These results imply that our superimposition of CT images using the 3D coordinate system are useful to compare soft tissue changes before and after surgery. Further investigation for more information about the factors that influence facial morphology changes is necessary since the changes may not be uniform due to the individual variety of soft tissue characterization, and the direction and amount of maxillary movement by Le Fort I osteotomy.

著者

山田 大輔

出版者

公益社団法人 日本薬学会

雑誌

ファルマシア (ISSN:00148601)

巻号頁・発行日

vol.52, no.4, pp.347, 2016 (Released:2016-04-01)

参考文献数

3

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恐怖と食欲はともに生存に必須な本能である.動物が餌を探すなか天敵に遭遇した場合,恐怖を感じて危機回避行動が生じなければ捕食されてしまう.そして,この恐怖は記憶しておく必要がある(恐怖記憶).しかし,恐怖が強すぎて餌にありつけなければ餓死してしまう.つまり,動物の生存には恐怖と食欲のバランスを保つことが必要であり,それを実現するような神経機構が存在する可能性が考えられていた.この点についてVermaらは,空腹感が恐怖を司る神経回路をシナプス伝達レベルで修飾し,恐怖記憶を変化させること,その変化に摂食制御ペプチド受容体が関与することを報告したので紹介する.なお,本稿は下記の文献に基づいて,その研究成果を紹介するものである.1) Verma D. et al., Neuropsychopharmacology, 41, 431-439 (2016).2) Holzer P. et al., Neuropeptides, 46, 261-274 (2012).3) Pape H. C., Pare D., Physiol. Rev., 90, 419-463 (2010).

著者

横尾 智治 見汐 翔太 宮代 賢治 山田 大輔 安藤 梢 西嶋 尚彦

出版者

一般社団法人 日本体育学会

雑誌

日本体育学会大会予稿集

巻号頁・発行日

vol.59, 2008

著者

森山 太揮 澤野 宏隆 高原 千咲 山田 大輔 林 靖之

出版者

一般社団法人 日本集中治療医学会

雑誌

日本集中治療医学会雑誌 (ISSN:13407988)

巻号頁・発行日

vol.28, no.2, pp.121-122, 2021-03-01 (Released:2021-03-01)

参考文献数

4